Gene: Grxcr1 (glutaredoxin and cysteine rich domain containing 1) Rattus norvegicus
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Symbol: Grxcr1
Name: glutaredoxin and cysteine rich domain containing 1
Description: ENCODES a protein that exhibits electron transfer activity (inferred); protein disulfide oxidoreductase activity (inferred); INVOLVED IN inner ear auditory receptor cell differentiation (ortholog); inner ear development (ortholog); inner ear receptor cell development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 25 (ortholog); Deafness (ortholog); Hearing Loss (ortholog); FOUND IN kinocilium (ortholog); stereocilium (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; toluene
AGR Description: Predicted to have electron transfer activity and protein disulfide oxidoreductase activity; predicted to be involved in animal organ development, negative regulation of phosphatase activity, and sensory perception of sound; predicted to localize to the kinocilium and stereocilium; orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1).
Merged Description: Predicted to have electron transfer activity and protein disulfide oxidoreductase activity; predicted to be involved in animal organ development, negative regulation of phosphatase activity, and sensory perception of sound; predicted to localize to the kinocilium and stereocilium; orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; toluene.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: glutaredoxin domain-containing cysteine-rich protein 1; glutaredoxin, cysteine rich 1; LOC498355; RGD1564635; similar to CG12206-PA, isoform A
Orthologs:
Homo sapiens (human) : GRXCR1 (glutaredoxin and cysteine rich domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Grxcr1 (glutaredoxin, cysteine rich 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grxcr1 (glutaredoxin and cysteine rich domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GRXCR1 (glutaredoxin and cysteine rich domain containing 1)
Canis lupus familiaris (dog) : GRXCR1 (glutaredoxin and cysteine rich domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grxcr1 (glutaredoxin and cysteine rich domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01441,663,688 - 41,787,331 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01441,461,233 - 41,583,874 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41442,605,908 - 42,728,503 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1439,172,879 - 39,287,730 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Grxcr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564635
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.