Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SUSD4 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Susd4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SUSD4 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of SUSD4 mRNA | CTD | PMID:28960355 | 17beta-estradiol | multiple interactions | ISO | SUSD4 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SUSD4 mRNA | CTD | PMID:19619570 | 17beta-estradiol | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SUSD4 mRNA | CTD | PMID:19619570 and PMID:31614463 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Susd4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Susd4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | SUSD4 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SUSD4 mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SUSD4 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SUSD4 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SUSD4 mRNA | CTD | PMID:26290441 and PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Susd4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SUSD4 mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SUSD4 mRNA | CTD | PMID:19619570 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:32119087 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SUSD4 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SUSD4 mRNA | CTD | PMID:36041667 | 4-hydroxyphenyl retinamide | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SUSD4 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SUSD4 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of SUSD4 mRNA | CTD | PMID:22100608 | aflatoxin B1 | increases methylation | ISO | SUSD4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SUSD4 intron | CTD | PMID:30157460 | aflatoxin M1 | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of SUSD4 mRNA | CTD | PMID:30928695 | aristolochic acid A | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SUSD4 mRNA | CTD | PMID:33212167 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of SUSD4 gene | CTD | PMID:28931070 and PMID:35440735 | benzo[a]pyrene | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of SUSD4 mRNA | CTD | PMID:20498004 and PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | SUSD4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SUSD4 exon | CTD | PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | SUSD4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SUSD4 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SUSD4 mRNA | CTD | PMID:23735875 | benzo[a]pyrene | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SUSD4 mRNA | CTD | PMID:22228805 | benzo[b]fluoranthene | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of SUSD4 mRNA | CTD | PMID:26377693 | Benzo[k]fluoranthene | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of SUSD4 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SUSD4 mRNA | CTD | PMID:25181051 more ... | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SUSD4 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SUSD4 protein | CTD | PMID:33376534 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SUSD4 gene | CTD | PMID:28505145 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SUSD4 mRNA | CTD | PMID:36041667 | bortezomib | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of SUSD4 mRNA | CTD | PMID:20977926 | butanal | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of SUSD4 mRNA | CTD | PMID:26079696 | cadmium dichloride | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of SUSD4 mRNA | CTD | PMID:26472689 | carbon nanotube | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | clothianidin | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | clothianidin results in increased expression of SUSD4 mRNA | CTD | PMID:31626844 | doxorubicin | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SUSD4 mRNA | CTD | PMID:29803840 | epoxiconazole | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of SUSD4 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | ISO | Susd4 (Mus musculus) | 6480464 | Ethanol affects the splicing of SUSD4 mRNA | CTD | PMID:30319688 | fenthion | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | Fenthion results in increased expression of SUSD4 mRNA | CTD | PMID:34813904 | folic acid | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SUSD4 mRNA | CTD | PMID:25629700 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of SUSD4 gene | CTD | PMID:22079235 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SUSD4 mRNA | CTD | PMID:33387578 | lead(0) | affects expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Lead affects the expression of SUSD4 mRNA | CTD | PMID:28903495 | methidathion | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | methidathion results in increased expression of SUSD4 mRNA | CTD | PMID:34813904 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of SUSD4 gene | CTD | PMID:35440735 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of SUSD4 mRNA | CTD | PMID:28801915 | O-methyleugenol | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of SUSD4 mRNA | CTD | PMID:32234424 | paracetamol | affects expression | ISO | Susd4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SUSD4 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SUSD4 mRNA | CTD | PMID:26690555 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SUSD4 mRNA | CTD | PMID:32680482 | PCB138 | multiple interactions | ISO | Susd4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | perfluorohexanesulfonic acid | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of SUSD4 mRNA | CTD | PMID:25812627 | perfluorononanoic acid | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of SUSD4 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SUSD4 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Susd4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SUSD4 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of SUSD4 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of SUSD4 mRNA | CTD | PMID:25812627 | phenobarbital | multiple interactions | ISO | Susd4 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SUSD4 mRNA] | CTD | PMID:19482888 | phenobarbital | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of SUSD4 mRNA | CTD | PMID:19270015 more ... | pirinixic acid | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of SUSD4 mRNA | CTD | PMID:20813756 | propiconazole | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | propiconazole results in decreased expression of SUSD4 mRNA | CTD | PMID:21278054 | silicon dioxide | decreases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SUSD4 mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of SUSD4 mRNA | CTD | PMID:34973136 | sodium arsenite | multiple interactions | ISO | SUSD4 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of and affects the splicing of SUSD4 mRNA | CTD | PMID:25879800 | sodium arsenite | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SUSD4 mRNA | CTD | PMID:34032870 | testosterone | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | Testosterone results in increased expression of SUSD4 mRNA | CTD | PMID:20844152 | tetrachloromethane | decreases expression | ISO | Susd4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of SUSD4 mRNA | CTD | PMID:27339419 more ... | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SUSD4 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SUSD4 mRNA] | CTD | PMID:31150632 | triptonide | increases expression | ISO | Susd4 (Mus musculus) | 6480464 | triptonide results in increased expression of SUSD4 mRNA | CTD | PMID:33045310 | valproic acid | decreases methylation | ISO | SUSD4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SUSD4 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SUSD4 mRNA | CTD | PMID:19101580 more ... | valproic acid | affects expression | ISO | SUSD4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SUSD4 mRNA | CTD | PMID:25979313 | |