Eda2r (ectodysplasin A2 receptor) - Rat Genome Database
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Gene: Eda2r (ectodysplasin A2 receptor) Rattus norvegicus
Analyze
Symbol: Eda2r
Name: ectodysplasin A2 receptor
RGD ID: 1564025
Description: Predicted to have signaling receptor activity. Predicted to be involved in intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of NF-kappaB transcription factor activity; and positive regulation of intracellular signal transduction. Predicted to localize to plasma membrane. Orthologous to human EDA2R (ectodysplasin A2 receptor); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH bisphenol A; Echimidine; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: ectodysplasin A2 isoform receptor; LOC296872; RGD1564025; similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor); similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor); tumor necrosis factor receptor superfamily member 27
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X62,224,763 - 62,269,344 (-)NCBI
Rnor_6.0 EnsemblX66,561,286 - 66,602,506 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X66,560,200 - 66,602,509 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X67,389,639 - 67,430,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X85,010,195 - 85,049,670 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX62,627,786 - 62,667,518 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:11039935   PMID:12270937   PMID:20434500  


Genomics

Comparative Map Data
Eda2r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X62,224,763 - 62,269,344 (-)NCBI
Rnor_6.0 EnsemblX66,561,286 - 66,602,506 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X66,560,200 - 66,602,509 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X67,389,639 - 67,430,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X85,010,195 - 85,049,670 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX62,627,786 - 62,667,518 (-)NCBICelera
Cytogenetic MapXq22NCBI
EDA2R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX66,595,637 - 66,639,298 (-)EnsemblGRCh38hg38GRCh38
GRCh38X66,594,384 - 66,639,303 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X65,815,479 - 65,859,111 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X65,815,479 - 65,859,140 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X65,732,204 - 65,752,598 (-)NCBINCBI36hg18NCBI36
Build 34X65,598,503 - 65,618,894NCBI
CeleraX66,163,047 - 66,183,441 (-)NCBI
Cytogenetic MapXq12NCBI
HuRefX59,642,932 - 59,686,455 (-)NCBIHuRef
CHM1_1X65,708,158 - 65,751,820 (-)NCBICHM1_1
Eda2r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X96,377,447 - 96,420,815 (-)NCBIGRCm39mm39
GRCm38X97,333,837 - 97,377,234 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX97,333,840 - 97,377,216 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X94,529,180 - 94,572,548 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X93,538,638 - 93,579,891 (-)NCBImm8
CeleraX84,324,759 - 84,367,800 (-)NCBICelera
Cytogenetic MapXC3NCBI
Eda2r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554756,087,687 - 6,143,432 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554756,080,153 - 6,143,339 (-)NCBIChiLan1.0ChiLan1.0
EDA2R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X65,851,559 - 65,894,775 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX65,850,306 - 65,894,975 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X55,786,361 - 55,830,798 (-)NCBIMhudiblu_PPA_v0panPan3
Eda2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366351,303,855 - 1,335,766 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EDA2R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X52,522,231 - 52,533,080 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EDA2R
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X56,527,838 - 56,574,646 (-)NCBI
ChlSab1.1 EnsemblX56,531,860 - 56,574,448 (-)Ensembl
Eda2r
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624898643,941 - 679,421 (+)NCBI

Position Markers
EDA2R  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X66,567,152 - 66,567,825NCBIRnor6.0
Rnor_5.0X67,396,583 - 67,397,256UniSTSRnor5.0
RGSC_v3.4X85,015,294 - 85,015,967UniSTSRGSC3.4
CeleraX62,634,738 - 62,635,411UniSTS
Cytogenetic MapXq31UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6139809770352120Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:35
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000017429
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 1 1
Low 42 19 4 10 4 7 9 35 13 35 9 7
Below cutoff 1 1 25 24 9 24 1 39 19 4 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000017429   ⟹   ENSRNOP00000017429
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX66,562,044 - 66,602,506 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076510   ⟹   ENSRNOP00000068211
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX66,561,286 - 66,602,458 (-)Ensembl
RefSeq Acc Id: XM_006227365   ⟹   XP_006227427
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX62,627,786 - 62,667,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227366   ⟹   XP_006227428
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX62,627,786 - 62,667,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257051   ⟹   XP_006257113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X62,224,763 - 62,269,344 (-)NCBI
Rnor_6.0X66,560,200 - 66,602,509 (-)NCBI
Rnor_5.0X67,389,639 - 67,430,026 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257052   ⟹   XP_006257114
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X62,224,763 - 62,269,333 (-)NCBI
Rnor_6.0X66,560,200 - 66,602,509 (-)NCBI
Rnor_5.0X67,389,639 - 67,430,026 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008758447   ⟹   XP_008756669
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX62,627,786 - 62,667,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773299   ⟹   XP_008771521
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X66,560,200 - 66,602,509 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039100197   ⟹   XP_038956125
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X62,224,763 - 62,269,322 (-)NCBI
RefSeq Acc Id: XM_039100198   ⟹   XP_038956126
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X62,224,763 - 62,269,322 (-)NCBI
RefSeq Acc Id: XM_039100199   ⟹   XP_038956127
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X62,224,763 - 62,269,333 (-)NCBI
RefSeq Acc Id: XM_039100200   ⟹   XP_038956128
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X62,224,763 - 62,269,332 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006227427   ⟸   XM_006227365
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006227428   ⟸   XM_006227366
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006257113   ⟸   XM_006257051
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006257114   ⟸   XM_006257052
- Peptide Label: isoform X4
- UniProtKB: A0A096MJP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008756669   ⟸   XM_008758447
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771521   ⟸   XM_008773299
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000017429   ⟸   ENSRNOT00000017429
RefSeq Acc Id: ENSRNOP00000068211   ⟸   ENSRNOT00000076510
RefSeq Acc Id: XP_038956127   ⟸   XM_039100199
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038956128   ⟸   XM_039100200
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038956126   ⟸   XM_039100198
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038956125   ⟸   XM_039100197
- Peptide Label: isoform X1
Protein Domains
TNFR-Cys

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701857
Promoter ID:EPDNEW_R12377
Type:multiple initiation site
Name:Eda2r_1
Description:ectodysplasin A2 receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X66,602,455 - 66,602,515EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564025 AgrOrtholog
Ensembl Genes ENSRNOG00000013018 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017429 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000068211 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017429 UniProtKB/TrEMBL
  ENSRNOT00000076510 UniProtKB/TrEMBL
InterPro TNFR_27 UniProtKB/TrEMBL
  TNFR_Cys_rich_reg UniProtKB/TrEMBL
  TNFRSF27_N UniProtKB/TrEMBL
NCBI Gene 296872 ENTREZGENE
PANTHER PTHR12120:SF8 UniProtKB/TrEMBL
Pfam TNFR_c6 UniProtKB/TrEMBL
PhenoGen Eda2r PhenoGen
PRINTS TNFACTORR27 UniProtKB/TrEMBL
PROSITE TNFR_NGFR_1 UniProtKB/TrEMBL
  TNFR_NGFR_2 UniProtKB/TrEMBL
SMART TNFR UniProtKB/TrEMBL
UniProt A0A096MJP5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D3ZAX4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Eda2r  ectodysplasin A2 receptor  Eda2r  ectodysplasin A2 isoform receptor   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Eda2r  ectodysplasin A2 isoform receptor   Eda2r_predicted  ectodysplasin A2 isoform receptor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Eda2r_predicted  ectodysplasin A2 isoform receptor (predicted)  RGD1564025_predicted  similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-10 RGD1564025_predicted  similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (predicted)    similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1564025_predicted  similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor) (predicted)  LOC296872  similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC296872  similar to Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)      Symbol and Name status set to provisional 70820 PROVISIONAL