Magea10 (MAGE family member A10) - Rat Genome Database

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Gene: Magea10 (MAGE family member A10) Rattus norvegicus
Analyze
Symbol: Magea10
Name: MAGE family member A10
RGD ID: 1563693
Description: Predicted to be located in cytosol and nucleoplasm. Orthologous to several human genes including MAGEA10 (MAGE family member A10); INTERACTS WITH vinclozolin; 2,2',4,4'-Tetrabromodiphenyl ether (ortholog); 2,4,6-tribromophenol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293832; melanoma antigen family A, 10; melanoma-associated antigen 10; RGD1563693; similar to melanoma antigen family A, 10
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X150,212,001 - 150,218,253 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX150,213,245 - 150,214,213 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X152,365,785 - 152,371,961 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX152,366,893 - 152,367,861 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01148,095,023 - 148,099,888 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X158,161,275 - 158,162,243 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1131,188,340 - 131,193,205 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Magea10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X150,212,001 - 150,218,253 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX150,213,245 - 150,214,213 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X152,365,785 - 152,371,961 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX152,366,893 - 152,367,861 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01148,095,023 - 148,099,888 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X158,161,275 - 158,162,243 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1131,188,340 - 131,193,205 (-)NCBICelera
Cytogenetic MapXq37NCBI
MAGEA10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X152,133,310 - 152,138,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX152,133,310 - 152,138,578 (-)EnsemblGRCh38hg38GRCh38
GRCh37X151,301,782 - 151,307,049 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X151,053,547 - 151,057,681 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X150,973,477 - 150,977,593NCBI
CeleraX151,548,374 - 151,552,508 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX140,155,676 - 140,160,867 (-)NCBIHuRef
CHM1_1X151,176,536 - 151,181,809 (-)NCBICHM1_1
T2T-CHM13v2.0X150,399,374 - 150,404,642 (-)NCBIT2T-CHM13v2.0
Magea10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X71,425,476 - 71,430,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX71,425,476 - 71,430,464 (-)EnsemblGRCm39 Ensembl
GRCm38X72,381,870 - 72,386,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX72,381,870 - 72,386,858 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X69,627,209 - 69,632,197 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X68,634,696 - 68,636,106 (-)NCBIMGSCv36mm8
CeleraX63,347,166 - 63,352,154 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
MAGEA10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X151,664,072 - 151,669,313 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX151,665,271 - 151,666,368 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X141,706,481 - 141,711,724 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC102156856
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X119,870,208 - 119,874,269 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX105,252,754 - 105,256,817 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X122,090,617 - 122,094,683 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X118,811,025 - 118,815,085 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X121,293,967 - 121,298,021 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X121,176,373 - 121,180,439 (+)NCBIUU_Cfam_GSD_1.0
Magea10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X117,537,009 - 117,543,667 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936714717,931 - 718,967 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936714717,931 - 719,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAGEA10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX123,400,803 - 123,401,909 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X123,400,803 - 123,401,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MAGEA10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X126,703,290 - 126,706,356 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606564,502,250 - 64,503,362 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Magea10
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:102
Count of miRNA genes:83
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000052261
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system reproductive system
High
Medium
Low 18 18
Below cutoff 49 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000089414   ⟹   ENSRNOP00000070404
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX150,213,245 - 150,214,213 (-)Ensembl
Rnor_6.0 EnsemblX152,366,893 - 152,367,861 (-)Ensembl
RefSeq Acc Id: XM_006229518   ⟹   XP_006229580
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X150,212,001 - 150,218,253 (-)NCBI
Rnor_6.0X152,365,785 - 152,371,961 (-)NCBI
Rnor_5.01148,095,023 - 148,099,888 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001395765 (Get FASTA)   NCBI Sequence Viewer  
  XP_006229580 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL82832 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_006229580   ⟸   XM_006229518
- UniProtKB: A0A0G2JXU3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070404   ⟸   ENSRNOT00000089414
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JXU3-F1-model_v2 AlphaFold A0A0G2JXU3 1-322 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563693 AgrOrtholog
BioCyc Gene G2FUF-705 BioCyc
Ensembl Genes ENSRNOG00000052773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070404 ENTREZGENE
  ENSRNOP00000070404.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089414 ENTREZGENE
  ENSRNOT00000089414.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
KEGG Report rno:293832 UniProtKB/TrEMBL
NCBI Gene 293832 ENTREZGENE
PANTHER PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PhenoGen Magea10 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A0A0G2JXU3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Magea10  MAGE family member A10  Magea10  melanoma antigen family A, 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Magea10  melanoma antigen family A, 10   Magea10_predicted  melanoma antigen family A, 10 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Magea10_predicted  melanoma antigen family A, 10 (predicted)  RGD1563693_predicted  similar to melanoma antigen family A, 10 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1563693_predicted  similar to melanoma antigen family A, 10 (predicted)  LOC293832  similar to melanoma antigen family A, 10  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC293832  similar to melanoma antigen family A, 10      Symbol and Name status set to provisional 70820 PROVISIONAL