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Gene: Tlx1 (T-cell leukemia, homeobox 1) Rattus norvegicus
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Symbol: Tlx1
Name: T-cell leukemia, homeobox 1
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including animal organ formation; nervous system development; and spleen development. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in adult T-cell leukemia. Orthologous to human TLX1 (T cell leukemia homeobox 1); INTERACTS WITH 17beta-estradiol; bisphenol A; progesterone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC499361; RGD1563655; similar to transcription factor; T-cell leukemia homeobox protein 1
Orthologs:
Homo sapiens (human) : TLX1 (T cell leukemia homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Tlx1 (T cell leukemia, homeobox 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlx1 (T cell leukemia homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TLX1 (T cell leukemia homeobox 1)
Canis lupus familiaris (dog) : TLX1 (T cell leukemia homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlx1 (T cell leukemia homeobox 1)
Sus scrofa (pig) : TLX1 (T cell leukemia homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01264,893,033 - 264,899,424 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01272,335,445 - 272,341,792 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41250,255,343 - 250,261,604 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1239,816,138 - 239,822,399 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tlx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563655
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.