Rab33a (RAB33A, member RAS oncogene family)

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Gene: Rab33a (RAB33A, member RAS oncogene family) Rattus norvegicus

Analyze

Symbol:

Rab33a

Name:

RAB33A, member RAS oncogene family

RGD ID:

1563280

Description:

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in antigen processing and presentation. Predicted to be active in Golgi apparatus and endosome. Orthologous to human RAB33A (RAB33A, member RAS oncogene family); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC317580; RAB33A, member of RAS oncogene family; ras-related protein Rab-33A; RGD1563280; similar to Ras-related protein Rab-33A (Small GTP-binding protein S10)

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RAB33A (RAB33A, member RAS oncogene family)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rab33a (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rab33a (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RAB33A (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RAB33A (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rab33a (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RAB33A (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RAB33A (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rab33a (RAB33A, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PSAP (prosaposin)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RAB33A (RAB33A, member RAS oncogene family)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rab33a (RAB33A, member RAS oncogene family)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rab33a (RAB33A, member RAS oncogene family)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rab-33	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rab33a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	127,694,219 - 127,706,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	127,694,964 - 127,706,378 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	129,820,706 - 129,832,102 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	133,391,515 - 133,402,927 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	130,917,865 - 130,929,261 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	135,348,799 - 135,360,204 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	135,348,436 - 135,360,203 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	135,420,269 - 135,431,674 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	134,913,903 - 134,925,308 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	126,643,393 - 126,654,798 (+)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal recessive nonsyndromic deafness 9 (ISO)

Beta-Hydroxyisobutyryl CoA Deacylase Deficiency (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease type X (ISO)

Charcot-Marie-Tooth disease X-linked recessive 4 (ISO)

combined oxidative phosphorylation deficiency (ISO)

combined oxidative phosphorylation deficiency 6 (ISO)

genetic disease (ISO)

hypomyelinating leukodystrophy (ISO)

intellectual disability (ISO)

leukodystrophy (ISO)

neuropathy (ISO)

peripheral nervous system disease (ISO)

prostate cancer (ISO)

sensorineural hearing loss (ISO)

Sketetal Dysplasia Coarse Facies Mental Retardation (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

X-linked deafness 5 (ISO)

X-linked Spondyloepimetaphyseal Dysplasia with Hypomyelinating Leukodystrophy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

all-trans-retinoic acid (ISO)

arsenous acid (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

chloroacetaldehyde (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dimethylarsinic acid (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

ferroheme b (ISO)

formaldehyde (ISO)

heme b (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

mercury dibromide (ISO)

metformin (EXP)

methyl methanesulfonate (ISO)

methylarsonic acid (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

paracetamol (EXP)

paraquat (EXP)

pentanal (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

protein kinase inhibitor (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

sunitinib (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation (ISO)

Rab protein signal transduction (IEA)

Cellular Component

endosome (IBA)

Golgi apparatus (IBA)

membrane (IEA)

Molecular Function

GTP binding (IBA)

GTPase activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19717423	PMID:21383079	PMID:22740627	PMID:22972995	PMID:25871792

Genomics

Comparative Map Data

Rab33a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	127,694,219 - 127,706,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	127,694,964 - 127,706,378 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	129,820,706 - 129,832,102 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	133,391,515 - 133,402,927 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	130,917,865 - 130,929,261 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	135,348,799 - 135,360,204 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	135,348,436 - 135,360,203 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	135,420,269 - 135,431,674 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	134,913,903 - 134,925,308 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	126,643,393 - 126,654,798 (+)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

RAB33A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	130,110,623 - 130,184,870 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	130,171,962 - 130,184,870 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	129,305,936 - 129,318,844 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	129,133,454 - 129,146,525 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	129,031,307 - 129,044,378	NCBI
Celera	X	129,692,335 - 129,705,325 (+)	NCBI		Celera
Cytogenetic Map	X	q26.1	NCBI
HuRef	X	118,701,562 - 118,715,130 (+)	NCBI		HuRef
CHM1_1	X	129,217,402 - 129,230,486 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	128,429,426 - 128,503,675 (+)	NCBI		T2T-CHM13v2.0

Rab33a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	47,602,540 - 47,619,117 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	47,608,162 - 47,619,109 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	48,513,663 - 48,530,240 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	48,519,285 - 48,530,232 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	45,872,647 - 45,883,409 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	44,764,097 - 44,774,859 (+)	NCBI		MGSCv36	mm8
Celera	X	36,021,110 - 36,031,749 (+)	NCBI		Celera
Cytogenetic Map	X	A5	NCBI
cM Map	X	25.68	NCBI

Rab33a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955473	4,875,202 - 4,887,177 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955473	4,875,230 - 4,891,898 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAB33A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	X	129,593,388 - 129,608,845 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	119,298,428 - 119,311,625 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	129,591,231 - 129,605,214 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	129,591,222 - 129,605,214 (+)	Ensembl	panpan1.1		panPan2

RAB33A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	101,311,752 - 101,322,825 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	101,312,611 - 101,322,689 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	87,489,539 - 87,500,593 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	103,168,072 - 103,179,136 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	103,168,952 - 103,178,995 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	100,585,386 - 100,596,426 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	102,431,428 - 102,442,487 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	102,209,808 - 102,220,845 (+)	NCBI		UU_Cfam_GSD_1.0

Rab33a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	99,550,127 - 99,561,728 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936479	1,425,722 - 1,437,374 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936479	1,425,765 - 1,437,338 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB33A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	106,712,398 - 106,723,404 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	106,708,402 - 106,723,803 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	122,480,414 - 122,491,875 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAB33A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	105,421,709 - 105,437,206 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	105,424,290 - 105,437,169 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	42,850,170 - 42,864,050 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rab33a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624797	9,389,732 - 9,401,312 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624797	9,389,651 - 9,401,260 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rab33a
15 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	35
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000008868
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	100567703	150256146	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	112934952	138400867	Rat
634346	Insul4	Insulin level QTL 4	0		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	X	126975089	152453651	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	103312877	148312877	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	103312877	148312877	Rat
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	93956491	138956491	Rat

Markers in Region

D83277

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	127,706,245 - 127,706,343 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	135,360,072 - 135,360,169	NCBI	Rnor6.0
Rnor_5.0	X	135,431,542 - 135,431,639	UniSTS	Rnor5.0
RGSC_v3.4	X	134,925,176 - 134,925,273	UniSTS	RGSC3.4
Celera	X	126,654,666 - 126,654,763	UniSTS
Cytogenetic Map	X	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			8						68		4
Low	3	37	22	14	19	14	4	4	6	35	37	11	4
Below cutoff		6	24	24		24	4	7					4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000008868 ⟹ ENSRNOP00000008868

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	127,694,964 - 127,706,378 (+)	Ensembl
Rnor_6.0 Ensembl	X	135,348,436 - 135,360,203 (+)	Ensembl

RefSeq Acc Id:

NM_001108257 ⟹ NP_001101727

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	127,694,964 - 127,706,378 (+)	NCBI
Rnor_6.0	X	135,348,799 - 135,360,204 (+)	NCBI
Rnor_5.0	X	135,420,269 - 135,431,674 (+)	NCBI
RGSC_v3.4	X	134,913,903 - 134,925,308 (+)	RGD
Celera	X	126,643,393 - 126,654,798 (+)	RGD

Sequence:

show sequence

CCGCACACGAACACACACACACACACACACACACACACACACACACACACACGCACGCACGCAC
AAAGCTCTCTCGCTTTAAGCGCACTAACGTGGCCGCTTTCTTTGTGTGGAGCCCGCGAGTGGGG
TTGGGACCCGGGTCCTGTCCCGGGGAGATGGCGCAGCCCATCCTGGGCCATGGGAGCCTGCAGC
CCGCCTCAGCTGCTGGCTTAGCATCCTTGGAGCTCGACTCATCGATGGACCAGTACGTGCAGAT
TCGCATTTTCAAAATCATCGTGATTGGGGACTCCAACGTGGGCAAGACCTGCCTGACCTTCCGC
TTCTGCGGGGGTACTTTCCCAGACAAGACTGAGGCCACTATCGGTGTGGACTTCAGGGAGAAGA
CCGTGGAAATCGAGGGCGAGAAGATCAAGGTTCAGGTGTGGGACACGGCAGGACAAGAACGCTT
CCGTAAAAGCATGGTTGAGCATTATTACCGCAATGTGCATGCAGTGGTCTTTGTCTATGACGTC
ACCAAGATGACCTCCTTCACCAACTTAAAAATGTGGATCCAGGAATGCAATGGGCATGCTGTGC
CCCCGCTAGTCCCAAAGGTGCTTGTGGGTAACAAGTGTGACTTGAGGGAACAGATCCAGGTACC
CTCCAACTTAGCCCTGAAATTTGCTGATGCCCACAACATGCTCTTATTTGAGACATCAGCCAAG
GACCCCAAAGAAAGCCAGAATGTGGAGTCAATCTTCATGTGCCTGGCTTGCCGACTGAAGGCCC
AGAAATCCCTCTTGTACCGTGATGCTGAGAGGCAGCAAGGAAAGGTGCAGACACTGGAGTTCCC
ACAGGAAGCTAACAGTAAAACTTCCTGTCCTTGTTGAAACCAAATGGTGTAAATACTCGAGAGC
ACTGGAGTTTTTTCTTCCCCTTTTTTTCTGTGCCTGCATAATGCTCACACCTGCTTGTTTCCAT
ACAAACTAATATCAAAAATAAAATTTGTATAGATT

hide sequence

RefSeq Acc Id:

XM_039099851 ⟹ XP_038955779

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	127,694,219 - 127,705,931 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101727	(Get FASTA)	NCBI Sequence Viewer
	XP_038955779	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10919	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001101727 ⟸ NM_001108257

- UniProtKB:

D3ZCU8 (UniProtKB/TrEMBL), A6JMQ7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDK
TEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNL
KMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVE
SIFMCLACRLKAQKSLLYRDAERQQGKVQTLEFPQEANSKTSCPC

hide sequence

RefSeq Acc Id:

ENSRNOP00000008868 ⟸ ENSRNOT00000008868

RefSeq Acc Id:	XP_038955779 ⟸ XM_039099851
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZCU8-F1-model_v2	AlphaFold	D3ZCU8	1-237	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563280	AgrOrtholog
BioCyc Gene	G2FUF-1129	BioCyc
Ensembl Genes	ENSRNOG00000006698	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000008868	ENTREZGENE
	ENSRNOP00000008868.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000008868	ENTREZGENE
	ENSRNOT00000008868.5	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Rab33A/B	UniProtKB/TrEMBL
	Ras_GTPase	UniProtKB/TrEMBL
	Small_GTP-bd	UniProtKB/TrEMBL
KEGG Report	rno:317580	UniProtKB/TrEMBL
NCBI Gene	317580	ENTREZGENE
PANTHER	PTHR47978	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB-33A	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PhenoGen	Rab33a	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A6JMQ7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZCU8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Rab33a	RAB33A, member of RAS oncogene family	Rab33a_predicted	RAB33A, member of RAS oncogene family (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Rab33a_predicted	RAB33A, member of RAS oncogene family (predicted)	RGD1563280_predicted	similar to Ras-related protein Rab-33A (Small GTP-binding protein S10) (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1563280_predicted	similar to Ras-related protein Rab-33A (Small GTP-binding protein S10) (predicted)	LOC317580	similar to Ras-related protein Rab-33A (Small GTP-binding protein S10)	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC317580	similar to Ras-related protein Rab-33A (Small GTP-binding protein S10)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar