Tmem185a (transmembrane protein 185A)

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Gene: Tmem185a (transmembrane protein 185A) Rattus norvegicus

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Symbol:

Tmem185a

Name:

transmembrane protein 185A

RGD ID:

1563037

Description:

Predicted to be located in membrane. Predicted to be active in dendrite. Orthologous to human TMEM185A (transmembrane protein 185A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC309357; RGD1563037; similar to family with sequence similarity 11, member A; transmembrane protein 185-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM185A (transmembrane protein 185A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Tmem185a (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem185a (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM185A (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM185A (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM185A (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM185A (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem185a (transmembrane protein 185A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TMEM185B (transmembrane protein 185B)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	TMEM185A (transmembrane protein 185A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem185a (transmembrane protein 185A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tmem185 (transmembrane protein 185)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG14194	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y116A8C.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tmem185a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	154,187,833 - 154,212,557 (+)	NCBI		GRCr8
mRatBN7.2	X	149,143,026 - 149,167,757 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	149,143,031 - 149,167,757 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	151,337,237 - 151,361,964 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	154,871,423 - 154,896,150 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	152,412,992 - 152,437,702 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	69,568,516 - 69,593,223 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	69,568,516 - 69,593,223 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	69,277,216 - 69,302,074 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	156,926,468 - 156,951,202 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	132,108,406 - 132,133,136 (-)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

antimycin A (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

azoxystrobin (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

CGP 52608 (ISO)

cyclosporin A (ISO)

deguelin (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

epoxiconazole (ISO)

ethanol (ISO)

fenpyroximate (ISO)

flutamide (EXP)

formaldehyde (ISO)

gentamycin (EXP)

indometacin (ISO)

leflunomide (EXP)

picoxystrobin (ISO)

pirinixic acid (ISO)

pyrimidifen (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

tebufenpyrad (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

dendrite (IBA,ISO)

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15525354

Genomics

Comparative Map Data

Tmem185a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	154,187,833 - 154,212,557 (+)	NCBI		GRCr8
mRatBN7.2	X	149,143,026 - 149,167,757 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	149,143,031 - 149,167,757 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	151,337,237 - 151,361,964 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	154,871,423 - 154,896,150 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	152,412,992 - 152,437,702 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	69,568,516 - 69,593,223 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	69,568,516 - 69,593,223 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	69,277,216 - 69,302,074 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	156,926,468 - 156,951,202 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	132,108,406 - 132,133,136 (-)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

TMEM185A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	149,596,556 - 149,631,792 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	149,596,556 - 149,631,912 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	148,678,216 - 148,713,437 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	148,486,015 - 148,521,375 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	148,383,869 - 148,419,229	NCBI
Celera	X	149,150,389 - 149,185,619 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	137,631,993 - 137,666,784 (-)	NCBI		HuRef
CHM1_1	X	148,639,114 - 148,674,389 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	147,862,307 - 147,897,566 (-)	NCBI		T2T-CHM13v2.0

Tmem185a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	69,503,359 - 69,520,796 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	69,503,359 - 69,520,786 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	70,459,753 - 70,477,180 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	70,459,753 - 70,477,180 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	67,713,231 - 67,730,218 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	66,720,612 - 66,737,599 (-)	NCBI		MGSCv36	mm8
Celera	X	61,444,048 - 61,460,959 (-)	NCBI		Celera
Cytogenetic Map	X	A7.2	NCBI
cM Map	X	36.04	NCBI

Tmem185a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955498	5,669,398 - 5,704,030 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955498	5,669,397 - 5,703,989 (+)	NCBI	ChiLan1.0	ChiLan1.0

TMEM185A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	149,422,807 - 149,458,213 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	149,426,412 - 149,461,818 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	139,161,465 - 139,196,943 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	149,087,980 - 149,123,265 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	149,087,980 - 149,123,265 (-)	Ensembl	panpan1.1		panPan2

TMEM185A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	117,952,095 - 117,968,098 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	117,953,515 - 117,966,342 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	120,155,783 - 120,191,582 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	117,118,940 - 117,154,742 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	119,213,410 - 119,249,180 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	119,181,222 - 119,217,005 (+)	NCBI		UU_Cfam_GSD_1.0

TMEM185A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	121,648,803 - 121,682,427 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	121,648,807 - 121,682,484 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	139,168,579 - 139,182,293 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM185A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	124,324,080 - 124,357,763 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	124,324,381 - 124,356,306 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	62,030,176 - 62,062,277 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem185a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624883	2,111,585 - 2,146,664 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624883	2,111,689 - 2,146,685 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem185a
7 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	605
Count of miRNA genes:	273
Interacting mature miRNAs:	329
Transcripts:	ENSRNOT00000066919
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	100567703	150256146	Rat
634346	Insul4	Insulin level QTL 4	0		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	X	126975089	152453651	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat

Markers in Region

RH133043

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	149,167,255 - 149,167,443 (-)	MAPPER	mRatBN7.2
Rnor_6.0	8	69,568,830 - 69,569,017	NCBI	Rnor6.0
Rnor_5.0	8	69,277,530 - 69,277,717	UniSTS	Rnor5.0
RGSC_v3.4	X	156,950,701 - 156,950,888	UniSTS	RGSC3.4
Celera	1	132,108,720 - 132,108,907	UniSTS
Cytogenetic Map	X	q37	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001135712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000066919 ⟹ ENSRNOP00000063850

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	149,143,031 - 149,167,757 (+)	Ensembl
Rnor_6.0 Ensembl	8	69,568,516 - 69,593,223 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095248 ⟹ ENSRNOP00000086966

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	149,143,072 - 149,167,752 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095252 ⟹ ENSRNOP00000089323

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	149,143,031 - 149,167,757 (+)	Ensembl

RefSeq Acc Id:

NM_001135712 ⟹ NP_001129184

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	154,187,833 - 154,212,557 (+)	NCBI
mRatBN7.2	X	149,143,031 - 149,167,757 (+)	NCBI
Rnor_6.0	8	69,568,516 - 69,593,223 (-)	NCBI
Rnor_5.0	8	69,277,216 - 69,302,074 (-)	NCBI
RGSC_v3.4	X	156,926,468 - 156,951,202 (+)	RGD
Celera	1	132,108,406 - 132,133,136 (-)	NCBI

Sequence:

show sequence

TACGGAAACCGGAAGGAGTGTCGGAGACAGTTGGTTGCTCTGGCTTCTCCCGTGGCGGCGTTGG
CGACAAGGCTGCCTTTAGCAGCATGAACCCGCTGTGAGGCGCAGGCTTCGCGGCGCGGGGGGCG
GGGGGAAGAGGAGGACGTCTAGGCGAAGTTCTCCGCCATGAACCTGAGGGGCCTCTTTCAGGAC
TTCAACCCGAGTAAATTCCTCATCTATGCTTGTTTGCTGCTGTTCTCTGTGCTACTAGCCCTTC
GTTTGGATGGCATCATTCAGTGGAGCTACTGGGCTGTCTTTGCTCCAATATGGTTATGGAAGTT
AATGGTCATTGTTGGCGCATCAGTTGGAACTGGAGTTTGGGCAAGAAATCCTCAATATCGAGCA
GAAGGAGAAACATGTGTGGAGTTTAAAGCCATGTTAATTGCTGTGGGCATCCATTTGCTCCTGC
TGATGTTTGAAGTTCTGGTCTGTGACAGGATTGAGAGAGGAAGCCATTTCTGGCTTCTGGTCTT
CATGCCATTGTTCTTTGTTTCCCCAGTGTCTGTTGCAGCATGTGTTTGGGGCTTTCGGCATGAC
AGGTCACTAGAGCTAGAAATCCTGTGTTCTGTCAACATTCTTCAGTTCATATTCATTGCCTTAA
GACTGGACAAGATCATCCACTGGCCCTGGCTTGTTGTATGTGTCCCTCTGTGGATTCTCATGTC
CTTCTTGTGCCTGGTGGTCCTCTATTACATCGTTTGGTCCGTTCTCTTCCTGCGCTCTATGGAT
GTGATTGCAGAACAACGCAGAACACATATAACCATGGCACTGAGCTGGATGACCATTGTCGTGC
CTCTTCTTACTTTTGAGATCCTGCTGGTTCACAAACTGGATGGCCACAACGCTTTCTCCTGTAT
TCCAATCTTTGTTCCCCTGTGGCTCTCATTGATCACACTGATGGCAACAACATTTGGACAGAAA
GGAGGAAACCACTGGTGGTTTGGTATTCGCAAAGATTTCTGCCAGTTTCTGCTTGAAATATTCC
CATTTTTGAGAGAGTATGGAAACATTTCATATGATCTCCACCATGAAGACAGTGAGGAAACAGA
AGAAACCCCAGTTCCAGAACCTCCTAAAATCGCACCTATGTTTCGCAAGAAGGCAAGGGTGGTC
ATCACACAGAGCCCTGGCAAGTATGTCCTTCCTCCACCCAAACTAAATATTGAAATGCCAGACT
AAAGGACCCTGCCAGGGCTAGAGTGTGTGCACACTGAAGGACACACTCCTACTCCCCTTGACCC
CAACCTGGACTTGGAACCTCAGACCTCCATCTGAAGCCTCGTTTGCATCCAGTGTCAGCCAGCC
ACTCAGAATGTAGGTGGCAGGGACTAAAGGTATCTATCAATATGGATGCCAGTGACACATGAGC
AAAGAACCCATTTCTTTCCGTATGGGTACCTGAAATGTGTTCTCATTCCTGTGGTACCCACCCA
GGGATAACTGATGCCTAGGCCCACAGAAAGCACATCTGTGGTCTGGGCAGCTTTTCTAGTGCTA
AAATTCCTATCAAAGTATTGAATGGAGTGGTTCTTATGGGACCACTTCCATTTGTGGTTCAGCT
GTGCTGCTTATAGGTAGCCAGTGGGGACTGTAACTAGGTCTGTACACATCTGTTGTGTTCAGAT
ACAGCCCAACCTTGCTTTCCTTGTCCCTGCTGGTCAGAAATTTCGCTTTAGGCAGGATGACAAC
AGGTTTGCAGGGCCTCATCAGTGAGCCCTTCCAAATGGCATGATTCCATGCCTGTATAGTATTT
ATACAGCTATTTTAGCACTGTAACATACAGTGTCAAATCCTAGTTCTGTACAGCATATTCTCTG
TTAAAGTATTTTTTTACAAGCTTGTGCTAGAGATGGATGGGTTAAGCTATGGGAGAAGCAGATA
GCTCAACTGCTTTGTCTCAGGCAGATGCCCCACCTTCACTTACCATGACCACTGACAATCTGGA
ATTCCTGCCAGCACAGCTACTACAAGTGAGGAAAGCTCTGTGCTTTTCCAACATGGGGTATGGG
AGAAGTGGCTTAACAGCCCAAGAAGTGCCCCTTGAGACCAGGACACTAGAGAAGGTTGCTAAGG
CAGGCCAGAAACAACCAGGGACTCCTGTCAAAGTCCAGAGCATTCTGCCCACCTGCAAGAAAAA
CACTGCACACTGAACATGCAGATACGATCACCTGTTAGTAGTTTCTCCAGGCTCTGCTGGTATA
GCCATCATACCAGAAAAATAACCTTCAGTCTAAATCAAATGATTCATTTCCCAATGGAAGTAAA
GGGAGCCTTGATCTTTCTGATCAGGAGGTATAATGTGTTTTCATGGTCACCTGGTCAGTAGCTT
CAGTCACACATAATTGAAGTCTACTATGACACAAATCCTACCCTTGGCACAGGCTTCCAGTGAG
CCTATTCTGTTTCAGGAGAAAGGGGAAACAGTGTAGCATTTTTTTGTTTGGTCTCTTAAAAATG
TGGTTAAATCCACTATTTTTGCTCCTGTAGTTCAATAAAGTGATTCATTTTACATGT

hide sequence

RefSeq Acc Id:

XM_039099686 ⟹ XP_038955614

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	154,187,835 - 154,212,552 (+)	NCBI
mRatBN7.2	X	149,143,027 - 149,167,752 (+)	NCBI

RefSeq Acc Id:

XM_063279974 ⟹ XP_063136044

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	154,194,680 - 154,212,552 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001129184	(Get FASTA)	NCBI Sequence Viewer
	XP_038955614	(Get FASTA)	NCBI Sequence Viewer
	XP_063136044	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL82747	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063850.1
	ENSRNOP00000086966.1
	ENSRNOP00000089323.1

RefSeq Acc Id:

NP_001129184 ⟸ NM_001135712

- UniProtKB:

D3ZWX2 (UniProtKB/TrEMBL), A6KUA5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGV
WARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVA
ACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVW
SVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLIT
LMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAP
MFRKKARVVITQSPGKYVLPPPKLNIEMPD

hide sequence

Ensembl Acc Id:

ENSRNOP00000063850 ⟸ ENSRNOT00000066919

RefSeq Acc Id:	XP_038955614 ⟸ XM_039099686
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A7Y0 (UniProtKB/TrEMBL), A6KUA5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000089323 ⟸ ENSRNOT00000095252

Ensembl Acc Id:

ENSRNOP00000086966 ⟸ ENSRNOT00000095248

RefSeq Acc Id:	XP_063136044 ⟸ XM_063279974
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZWX2-F1-model_v2	AlphaFold	D3ZWX2	1-350	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696067

Promoter ID:

EPDNEW_R6592

Type:

initiation region

Name:

Tmem185a_1

Description:

transmembrane protein 185A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	69,593,195 - 69,593,255	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563037	AgrOrtholog
BioCyc Gene	G2FUF-727	BioCyc
Ensembl Genes	ENSRNOG00000011047	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000066919.2	UniProtKB/TrEMBL
	ENSRNOT00000095248.1	UniProtKB/TrEMBL
	ENSRNOT00000095252.1	UniProtKB/TrEMBL
InterPro	TM_Fragile-X-F-assoc	UniProtKB/TrEMBL
KEGG Report	rno:309357	UniProtKB/TrEMBL
NCBI Gene	309357	ENTREZGENE
PANTHER	PTHR13568	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 185-LIKE	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 185A	UniProtKB/TrEMBL
Pfam	Tmemb_185A	UniProtKB/TrEMBL
PhenoGen	Tmem185a	PhenoGen
RatGTEx	ENSRNOG00000011047	RatGTEx
UniProt	A0A8I6A2B9_RAT	UniProtKB/TrEMBL
	A0A8I6A7Y0	ENTREZGENE, UniProtKB/TrEMBL
	A6KUA5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZWX2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-12-01	Tmem185a	transmembrane protein 185A	RGD1563037	similar to family with sequence similarity 11, member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1563037	similar to family with sequence similarity 11, member A	RGD1563037_predicted	similar to family with sequence similarity 11, member A (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1563037_predicted	similar to family with sequence similarity 11, member A (predicted)	LOC309357	similar to family with sequence similarity 11, member A	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC309357	similar to family with sequence similarity 11, member A			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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