Acap2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2) - Rat Genome Database

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Gene: Acap2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2) Rattus norvegicus
Analyze
Symbol: Acap2
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
RGD ID: 1562939
Description: Predicted to enable GTPase activator activity; phosphatidylinositol-3,5-bisphosphate binding activity; and small GTPase binding activity. Involved in cellular response to nerve growth factor stimulus and endocytic recycling. Located in endosome membrane. Orthologous to human ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; centaurin, beta 2; centaurin-beta-2; Centb2; cnt-b2; similar to Centaurin beta 2 (Cnt-b2)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21169,538,487 - 69,654,156 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1169,538,546 - 69,654,151 (+)Ensembl
Rnor_6.01173,078,966 - 73,193,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,078,982 - 73,191,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01176,151,871 - 76,266,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,411,706 - 71,524,828 (+)NCBIRGSC3.4rn4RGSC3.4
Celera11602,159 - 617,137 (-)NCBICelera
Celera1168,958,302 - 69,050,569 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
endosome membrane  (IBA,IDA)
ruffle  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:11001876   PMID:11062263   PMID:19946888   PMID:22344257   PMID:24600047   PMID:25694427  


Genomics

Comparative Map Data
Acap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21169,538,487 - 69,654,156 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1169,538,546 - 69,654,151 (+)Ensembl
Rnor_6.01173,078,966 - 73,193,496 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,078,982 - 73,191,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01176,151,871 - 76,266,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41171,411,706 - 71,524,828 (+)NCBIRGSC3.4rn4RGSC3.4
Celera11602,159 - 617,137 (-)NCBICelera
Celera1168,958,302 - 69,050,569 (+)NCBICelera
Cytogenetic Map11q22NCBI
ACAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383195,274,745 - 195,443,020 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3195,274,745 - 195,443,044 (-)EnsemblGRCh38hg38GRCh38
GRCh373194,995,474 - 195,163,749 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363196,476,768 - 196,645,041 (-)NCBINCBI36hg18NCBI36
Build 343196,476,775 - 196,645,049NCBI
Celera3193,403,894 - 193,572,181 (-)NCBI
Cytogenetic Map3q29NCBI
HuRef3192,371,085 - 192,539,531 (-)NCBIHuRef
CHM1_13194,958,324 - 195,126,679 (-)NCBICHM1_1
Acap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391630,911,230 - 31,020,105 (-)NCBIGRCm39mm39
GRCm39 Ensembl1630,911,230 - 31,020,063 (-)Ensembl
GRCm381631,092,412 - 31,201,285 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1631,092,412 - 31,201,245 (-)EnsemblGRCm38mm10GRCm38
MGSCv371631,092,499 - 31,201,324 (-)NCBIGRCm37mm9NCBIm37
MGSCv361631,012,160 - 31,120,985 (-)NCBImm8
Celera1631,599,552 - 31,709,042 (-)NCBICelera
Cytogenetic Map16B2NCBI
Acap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542013,650,215 - 13,773,022 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542013,649,482 - 13,777,353 (+)NCBIChiLan1.0ChiLan1.0
ACAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13202,876,826 - 203,048,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3202,876,819 - 203,048,239 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03192,577,813 - 192,750,435 (-)NCBIMhudiblu_PPA_v0panPan3
ACAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13330,588,450 - 30,717,162 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3330,587,756 - 30,716,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3330,616,392 - 30,748,126 (+)NCBI
ROS_Cfam_1.03330,842,887 - 30,971,404 (+)NCBI
ROS_Cfam_1.0 Ensembl3330,842,829 - 30,973,794 (+)Ensembl
UMICH_Zoey_3.13330,637,602 - 30,769,036 (+)NCBI
UNSW_CanFamBas_1.03330,673,447 - 30,804,928 (+)NCBI
UU_Cfam_GSD_1.03331,296,464 - 31,424,933 (+)NCBI
Acap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602143,758,740 - 143,864,040 (+)NCBI
SpeTri2.0NW_00493683373,752 - 179,057 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13132,273,874 - 132,431,442 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113132,274,229 - 132,431,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213141,934,497 - 141,974,905 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11589,341,026 - 89,516,816 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1589,340,947 - 89,516,815 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604163,073,360 - 63,280,046 (-)NCBIVero_WHO_p1.0
Acap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473062,642,897 - 62,770,816 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH132336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,648,646 - 69,648,862 (+)MAPPERmRatBN7.2
Rnor_6.01173,188,589 - 73,188,804NCBIRnor6.0
Rnor_5.01176,260,010 - 76,260,225UniSTSRnor5.0
RGSC_v3.41171,522,284 - 71,522,499UniSTSRGSC3.4
Celera11605,354 - 605,569UniSTS
RH 3.4 Map11554.33UniSTS
Cytogenetic Map11q22UniSTS
BI296803  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,538,146 - 69,538,319 (+)MAPPERmRatBN7.2
Rnor_6.01173,078,583 - 73,078,755NCBIRnor6.0
Rnor_5.01176,151,476 - 76,151,648UniSTSRnor5.0
RGSC_v3.41171,411,307 - 71,411,479UniSTSRGSC3.4
Celera1168,957,905 - 68,958,077UniSTS
RH 3.4 Map11404.7UniSTS
Cytogenetic Map11q22UniSTS
AU047727  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,540,490 - 69,540,658 (+)MAPPERmRatBN7.2
Rnor_6.01173,080,925 - 73,081,092NCBIRnor6.0
Rnor_5.01176,153,819 - 76,153,986UniSTSRnor5.0
RGSC_v3.41171,413,649 - 71,413,816UniSTSRGSC3.4
Celera1168,960,245 - 68,960,412UniSTS
Cytogenetic Map11q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
4889859Pur28Proteinuria QTL 2819.50.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:278
Count of miRNA genes:185
Interacting mature miRNAs:212
Transcripts:ENSRNOT00000029549
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 33 40 24 19 24 4 4 74 34 41 11 4
Low 10 17 17 17 4 7 1 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029549   ⟹   ENSRNOP00000030250
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1169,538,546 - 69,651,191 (+)Ensembl
Rnor_6.0 Ensembl1173,078,982 - 73,191,132 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080834   ⟹   ENSRNOP00000073162
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1169,586,554 - 69,654,151 (+)Ensembl
Rnor_6.0 Ensembl1173,079,168 - 73,190,350 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094946   ⟹   ENSRNOP00000082482
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1169,538,546 - 69,651,191 (+)Ensembl
RefSeq Acc Id: NM_001034006   ⟹   NP_001029178
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,546 - 69,651,191 (+)NCBI
Rnor_6.01173,078,982 - 73,191,133 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
RGSC_v3.41171,411,706 - 71,524,828 (+)RGD
Celera1168,958,302 - 69,050,569 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248487   ⟹   XP_006248549
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,489 - 69,654,156 (+)NCBI
Rnor_6.01173,078,968 - 73,193,496 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248489   ⟹   XP_006248551
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,490 - 69,654,156 (+)NCBI
Rnor_6.01173,078,968 - 73,193,496 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248491   ⟹   XP_006248553
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,492 - 69,654,156 (+)NCBI
Rnor_6.01173,078,969 - 73,193,496 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598065   ⟹   XP_017453554
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,488 - 69,654,156 (+)NCBI
Rnor_6.01173,078,966 - 73,193,496 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598066   ⟹   XP_017453555
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,489 - 69,654,156 (+)NCBI
Rnor_6.01173,078,968 - 73,193,496 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598067   ⟹   XP_017453556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,491 - 69,654,156 (+)NCBI
Rnor_6.01173,078,969 - 73,193,496 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005491053
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,487 - 69,654,156 (+)NCBI
RefSeq Acc Id: XR_005491054
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21169,538,487 - 69,654,156 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001029178   ⟸   NM_001034006
- UniProtKB: Q5FVC7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248549   ⟸   XM_006248487
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006248551   ⟸   XM_006248489
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006248553   ⟸   XM_006248491
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017453554   ⟸   XM_017598065
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017453555   ⟸   XM_017598066
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K4T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453556   ⟸   XM_017598067
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000073162   ⟸   ENSRNOT00000080834
RefSeq Acc Id: ENSRNOP00000030250   ⟸   ENSRNOT00000029549
RefSeq Acc Id: ENSRNOP00000082482   ⟸   ENSRNOT00000094946
Protein Domains
Arf-GAP   BAR   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVC7-F1-model_v2 AlphaFold Q5FVC7 1-770 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698224
Promoter ID:EPDNEW_R8748
Type:initiation region
Name:Acap2_1
Description:ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01173,079,095 - 73,079,155EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562939 AgrOrtholog
BioCyc Gene G2FUF-21050 BioCyc
Ensembl Genes ENSRNOG00000001730 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030250 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073162 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029549 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000080834 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000094946 ENTREZGENE
Gene3D-CATH 1.10.220.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114273 IMAGE-MGC_LOAD
InterPro ACAP1/2/3-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:619382 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93962 IMAGE-MGC_LOAD
NCBI Gene 619382 ENTREZGENE
PANTHER PTHR23180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGap UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Acap2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARFGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ArfGap UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57863 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K4T3 ENTREZGENE, UniProtKB/TrEMBL
  ACAP2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Acap2  ArfGAP with coiled-coil, ankyrin repeat and PH domains 2  LOC360727  similar to Centaurin beta 2 (Cnt-b2)  Data Merged 1643240 APPROVED
2008-10-15 Acap2  ArfGAP with coiled-coil, ankyrin repeat and PH domains 2  Centb2  centaurin, beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC360727  similar to Centaurin beta 2 (Cnt-b2)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 Centb2  centaurin, beta 2      Symbol and Name status set to provisional 70820 PROVISIONAL