Tdrd12 (tudor domain containing 12) - Rat Genome Database

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Gene: Tdrd12 (tudor domain containing 12) Rattus norvegicus
Analyze
Symbol: Tdrd12
Name: tudor domain containing 12
RGD ID: 1562792
Description: Predicted to have ATP binding activity and nucleic acid binding activity. Predicted to be involved in several processes, including gamete generation; gene silencing by RNA; and piRNA metabolic process. Predicted to localize to PET complex. Orthologous to human TDRD12 (tudor domain containing 12); INTERACTS WITH bisphenol A; endosulfan; vinclozolin.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC292813; LOC689639; putative ATP-dependent RNA helicase TDRD12; RGD1562792; similar to CG11133-PA; similar to RIKEN cDNA 2410004F06
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2188,133,271 - 88,205,729 (-)NCBI
Rnor_6.0 Ensembl191,740,933 - 91,811,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0191,739,126 - 91,811,577 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0192,865,962 - 92,939,297 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4188,009,688 - 88,027,194 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.4188,001,744 - 88,072,002 (-)NCBIRGSC3.4rn4RGSC3.4
Celera182,483,162 - 82,555,576 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:24067652   PMID:24270810   PMID:26669262  


Genomics

Comparative Map Data
Tdrd12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2188,133,271 - 88,205,729 (-)NCBI
Rnor_6.0 Ensembl191,740,933 - 91,811,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0191,739,126 - 91,811,577 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0192,865,962 - 92,939,297 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4188,009,688 - 88,027,194 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.4188,001,744 - 88,072,002 (-)NCBIRGSC3.4rn4RGSC3.4
Celera182,483,162 - 82,555,576 (-)NCBICelera
Cytogenetic Map1q21NCBI
TDRD12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1932,719,753 - 32,829,580 (+)EnsemblGRCh38hg38GRCh38
GRCh381932,719,767 - 32,829,580 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371933,210,673 - 33,320,486 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361937,902,499 - 38,004,006 (+)NCBINCBI36hg18NCBI36
Celera1929,904,299 - 29,975,332 (+)NCBI
Cytogenetic Map19q13.11NCBI
HuRef1929,713,951 - 29,784,334 (+)NCBIHuRef
CHM1_11933,211,966 - 33,282,865 (+)NCBICHM1_1
Tdrd12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39735,166,366 - 35,237,206 (-)NCBIGRCm39mm39
GRCm39 Ensembl735,168,523 - 35,237,170 (-)Ensembl
GRCm38735,466,941 - 35,537,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl735,469,098 - 35,537,745 (-)EnsemblGRCm38mm10GRCm38
MGSCv37736,278,629 - 36,322,763 (-)NCBIGRCm37mm9NCBIm37
MGSCv36735,202,370 - 35,246,442 (-)NCBImm8
Celera730,622,196 - 30,666,614 (-)NCBICelera
Cytogenetic Map7B2NCBI
Tdrd12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554685,141,077 - 5,275,748 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554685,201,216 - 5,277,062 (-)NCBIChiLan1.0ChiLan1.0
TDRD12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11938,386,216 - 38,489,791 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1938,386,557 - 38,489,791 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01929,638,686 - 29,750,249 (+)NCBIMhudiblu_PPA_v0panPan3
TDRD12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11119,229,721 - 119,290,101 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1119,231,485 - 119,290,086 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1118,629,868 - 118,700,287 (-)NCBI
ROS_Cfam_1.01119,830,747 - 119,901,232 (-)NCBI
UMICH_Zoey_3.11119,393,854 - 119,464,441 (-)NCBI
UNSW_CanFamBas_1.01119,014,335 - 119,084,954 (-)NCBI
UU_Cfam_GSD_1.01120,074,270 - 120,144,554 (-)NCBI
Tdrd12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093498,630,237 - 8,698,838 (+)NCBI
SpeTri2.0NW_0049365702,947,069 - 3,015,549 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TDRD12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl642,589,554 - 42,667,950 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1642,589,557 - 42,667,946 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2638,034,437 - 38,106,866 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TDRD12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1627,772,397 - 27,874,056 (+)NCBI
ChlSab1.1 Ensembl627,783,408 - 27,867,776 (+)Ensembl
Vero_WHO_p1.0NW_0236660735,356,529 - 5,461,474 (+)NCBI
Tdrd12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247947,641,105 - 7,740,091 (+)NCBI

Position Markers
D1Got91  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2188,190,179 - 88,190,280 (+)MAPPER
Rnor_6.0191,796,024 - 91,796,124NCBIRnor6.0
Rnor_5.0192,923,769 - 92,923,869UniSTSRnor5.0
RGSC_v3.4188,056,635 - 88,056,736RGDRGSC3.4
RGSC_v3.4188,056,636 - 88,056,736UniSTSRGSC3.4
RGSC_v3.1188,134,747 - 88,134,847RGD
RH 3.4 Map1867.2UniSTS
RH 3.4 Map1867.2RGD
RH 2.0 Map1556.2RGD
Cytogenetic Map1q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123406428108057505Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)125951907130917265Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134993530173445086Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13537750894364229Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135377692217372257Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143579208126240667Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143579208126240667Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143579208126240667Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143579208126240667Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143579208126240667Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)149147799156446783Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14957857794578577Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149578577169852184Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149578693217054291Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15052271494225616Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157761301104391981Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)158209327103209327Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)158354072161711996Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)164588516125875986Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)166113339122614963Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)16722768394201552Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)179134941113593716Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)179689548124689548Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17968976594909507Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)182788437239853971Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)183502376128502376Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)183656882126240667Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185779320130779320Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185917265130917265Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)186776571131776571Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)188634585106002500Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)190804143161321256Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)191093646136093646Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:35
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000017021
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5
Low 3 26 26
Below cutoff 3 18 17 1 19 1 7 7 33 5 10 9 7

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_017588860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC136661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000017021   ⟹   ENSRNOP00000017021
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl191,740,933 - 91,811,547 (-)Ensembl
RefSeq Acc Id: XM_017588860   ⟹   XP_017444349
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,483,162 - 82,555,576 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588866   ⟹   XP_017444355
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,483,162 - 82,555,576 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588867   ⟹   XP_017444356
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,483,162 - 82,555,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588869   ⟹   XP_017444358
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,483,162 - 82,555,576 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588872   ⟹   XP_017444361
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,483,162 - 82,545,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588874   ⟹   XP_017444363
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,492,414 - 82,555,576 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588875   ⟹   XP_017444364
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera182,483,162 - 82,555,576 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590062   ⟹   XP_017445551
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0191,739,126 - 91,811,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590063   ⟹   XP_017445552
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,273 - 88,205,729 (-)NCBI
Rnor_6.0191,739,126 - 91,811,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590064   ⟹   XP_017445553
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,273 - 88,205,470 (-)NCBI
Rnor_6.0191,739,126 - 91,811,360 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590065   ⟹   XP_017445554
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,273 - 88,204,734 (-)NCBI
Rnor_6.0191,739,126 - 91,811,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590066   ⟹   XP_017445555
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0191,739,126 - 91,801,415 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590067   ⟹   XP_017445556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0191,748,379 - 91,811,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017590068   ⟹   XP_017445557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0191,739,126 - 91,811,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039100860   ⟹   XP_038956788
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,273 - 88,204,734 (-)NCBI
RefSeq Acc Id: XM_039100861   ⟹   XP_038956789
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,273 - 88,205,729 (-)NCBI
RefSeq Acc Id: XM_039100862   ⟹   XP_038956790
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,272 - 88,197,478 (-)NCBI
RefSeq Acc Id: XM_039100863   ⟹   XP_038956791
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,272 - 88,181,941 (-)NCBI
RefSeq Acc Id: XM_039100864   ⟹   XP_038956792
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2188,133,271 - 88,157,138 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_017444355   ⟸   XM_017588866
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017444364   ⟸   XM_017588875
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017444358   ⟸   XM_017588869
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017444349   ⟸   XM_017588860
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017444356   ⟸   XM_017588867
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017444361   ⟸   XM_017588872
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017444363   ⟸   XM_017588874
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017445552   ⟸   XM_017590063
- Peptide Label: isoform X2
- UniProtKB: F1LTR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445557   ⟸   XM_017590068
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017445554   ⟸   XM_017590065
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017445551   ⟸   XM_017590062
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017445553   ⟸   XM_017590064
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017445555   ⟸   XM_017590066
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017445556   ⟸   XM_017590067
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000017021   ⟸   ENSRNOT00000017021
RefSeq Acc Id: XP_038956792   ⟸   XM_039100864
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038956790   ⟸   XM_039100862
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038956791   ⟸   XM_039100863
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038956789   ⟸   XM_039100861
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038956788   ⟸   XM_039100860
- Peptide Label: isoform X1
Protein Domains
CS

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562792 AgrOrtholog
Ensembl Genes ENSRNOG00000012719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017021 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017021 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.90 UniProtKB/TrEMBL
  2.60.40.790 UniProtKB/TrEMBL
InterPro CS-like_domain UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAD/DEAH_N UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Staphylococcal_nuclease/TUDOR UniProtKB/TrEMBL
  Tudor UniProtKB/TrEMBL
NCBI Gene 689639 ENTREZGENE
Pfam DEAD UniProtKB/TrEMBL
  PF04969 UniProtKB/TrEMBL
  TUDOR UniProtKB/TrEMBL
PhenoGen Tdrd12 PhenoGen
PROSITE PS51203 UniProtKB/TrEMBL
Superfamily-SCOP HSP20_chap UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt F1LTR3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-09-08 Tdrd12  tudor domain containing 12  LOC689639  similar to CG11133-PA  Data Merged 737654 APPROVED
2008-03-19 Tdrd12  tudor domain containing 12  RGD1562792_predicted  similar to RIKEN cDNA 2410004F06 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689639  similar to CG11133-PA      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1562792_predicted  similar to RIKEN cDNA 2410004F06 (predicted)  LOC292813  similar to RIKEN cDNA 2410004F06  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC292813  similar to RIKEN cDNA 2410004F06      Symbol and Name status set to provisional 70820 PROVISIONAL