Mier1 (MIER1 transcriptional regulator) - Rat Genome Database

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Gene: Mier1 (MIER1 transcriptional regulator) Rattus norvegicus
Analyze
Symbol: Mier1
Name: MIER1 transcriptional regulator
RGD ID: 1562337
Description: Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to contribute to histone deacetylase activity. Predicted to be involved in chromatin remodeling; negative regulation of transcription by RNA polymerase II; and positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in nucleus. Predicted to be part of transcription repressor complex. Predicted to be active in nucleoplasm. Orthologous to human MIER1 (MIER1 transcriptional regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC313418; mesoderm induction early response 1; mesoderm induction early response 1 homolog; mesoderm induction early response 1 homolog (Xenopus laevis); mesoderm induction early response 1, transcriptional regulator; mesoderm induction early response protein 1; MGC188399; RGD1562337; similar to mesoderm induction early response 1 (MI-ER1)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85123,105,114 - 123,156,653 (+)NCBIGRCr8
mRatBN7.25117,876,012 - 117,927,592 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5117,870,382 - 117,927,589 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5120,513,992 - 120,560,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05122,239,345 - 122,285,688 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05122,290,611 - 122,336,954 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05122,642,065 - 122,693,642 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5122,641,885 - 122,693,635 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05126,507,563 - 126,559,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45124,053,388 - 124,100,875 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5116,452,985 - 116,499,350 (+)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12482978   PMID:12761501   PMID:28046085  


Genomics

Comparative Map Data
Mier1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85123,105,114 - 123,156,653 (+)NCBIGRCr8
mRatBN7.25117,876,012 - 117,927,592 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5117,870,382 - 117,927,589 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5120,513,992 - 120,560,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05122,239,345 - 122,285,688 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05122,290,611 - 122,336,954 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05122,642,065 - 122,693,642 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5122,641,885 - 122,693,635 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05126,507,563 - 126,559,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45124,053,388 - 124,100,875 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5116,452,985 - 116,499,350 (+)NCBICelera
Cytogenetic Map5q33NCBI
MIER1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38166,924,990 - 66,988,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl166,924,895 - 66,988,619 (+)EnsemblGRCh38hg38GRCh38
GRCh37167,390,673 - 67,454,302 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,163,230 - 67,226,890 (+)NCBINCBI36Build 36hg18NCBI36
Celera165,680,527 - 65,744,235 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef165,499,357 - 65,562,966 (+)NCBIHuRef
CHM1_1167,505,934 - 67,569,616 (+)NCBICHM1_1
T2T-CHM13v2.0166,802,518 - 66,866,111 (+)NCBIT2T-CHM13v2.0
Mier1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394102,971,521 - 103,022,951 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4102,971,587 - 103,022,951 (+)EnsemblGRCm39 Ensembl
GRCm384103,114,324 - 103,165,754 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4103,114,390 - 103,165,754 (+)EnsemblGRCm38mm10GRCm38
MGSCv374102,787,070 - 102,838,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364102,612,397 - 102,663,681 (+)NCBIMGSCv36mm8
Celera4101,478,978 - 101,530,357 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map447.36NCBI
Mier1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542323,975,616 - 24,024,086 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542323,973,062 - 24,027,961 (-)NCBIChiLan1.0ChiLan1.0
MIER1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21159,872,098 - 159,935,150 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,032,281 - 159,095,233 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0166,174,143 - 66,237,114 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1168,059,115 - 68,122,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl168,059,694 - 68,122,354 (+)Ensemblpanpan1.1panPan2
MIER1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1543,531,847 - 43,590,102 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl543,533,035 - 43,590,041 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha543,657,744 - 43,714,131 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0543,719,301 - 43,775,717 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl543,717,383 - 43,775,670 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1543,685,225 - 43,741,628 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0543,631,168 - 43,687,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0543,871,383 - 43,927,753 (-)NCBIUU_Cfam_GSD_1.0
Mier1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505879,846,629 - 79,905,022 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365914,584,323 - 4,643,238 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365914,584,527 - 4,642,920 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIER1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6145,609,626 - 145,680,005 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16145,609,619 - 145,680,063 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MIER1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12066,125,152 - 66,189,758 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2066,129,006 - 66,183,992 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603351,405,770 - 51,469,651 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mier1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474228,045,353 - 28,098,060 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474228,043,349 - 28,100,675 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mier1
69 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:472
Count of miRNA genes:237
Interacting mature miRNAs:321
Transcripts:ENSRNOT00000066041
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
7794739Bp372Blood pressure QTL 3720.0058arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5117913688125222967Rat

Markers in Region
RH132276  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25117,927,238 - 117,927,436 (-)MAPPERmRatBN7.2
mRatBN7.25117,927,238 - 117,927,436 (+)MAPPERmRatBN7.2
mRatBN7.21388,998,731 - 88,998,929 (-)MAPPERmRatBN7.2
mRatBN7.21388,998,731 - 88,998,929 (+)MAPPERmRatBN7.2
Rnor_6.01395,130,485 - 95,130,682NCBIRnor6.0
Rnor_6.05122,693,285 - 122,693,482NCBIRnor6.0
Rnor_5.05126,558,805 - 126,559,002UniSTSRnor5.0
Rnor_5.01399,582,128 - 99,582,325UniSTSRnor5.0
RGSC_v3.45124,100,522 - 124,100,719UniSTSRGSC3.4
RGSC_v3.41392,859,717 - 92,859,914UniSTSRGSC3.4
Celera1388,578,423 - 88,578,620UniSTS
Celera5116,498,997 - 116,499,194UniSTS
RH 3.4 Map13601.4UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map13q24-q26UniSTS
RH138978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25117,875,950 - 117,876,072 (+)MAPPERmRatBN7.2
Rnor_6.05122,641,985 - 122,642,106NCBIRnor6.0
Rnor_5.05126,507,485 - 126,507,606UniSTSRnor5.0
RGSC_v3.45124,048,092 - 124,048,213UniSTSRGSC3.4
Celera5116,447,689 - 116,447,810UniSTS
RH 3.4 Map5754.6UniSTS
Cytogenetic Map5q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 55 39 19 39 8 10 74 35 39 11 8
Low 2 2 2 1 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001131012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC168252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000066041   ⟹   ENSRNOP00000063001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5117,881,248 - 117,927,589 (+)Ensembl
Rnor_6.0 Ensembl5122,647,281 - 122,693,635 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086765   ⟹   ENSRNOP00000075308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5122,641,885 - 122,690,916 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095676   ⟹   ENSRNOP00000085059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5117,870,382 - 117,927,589 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099770   ⟹   ENSRNOP00000081443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5117,870,382 - 117,927,589 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108735   ⟹   ENSRNOP00000083378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5117,870,382 - 117,927,589 (+)Ensembl
RefSeq Acc Id: NM_001131012   ⟹   NP_001124484
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,110,314 - 123,156,653 (+)NCBI
mRatBN7.25117,881,248 - 117,927,592 (+)NCBI
Rnor_6.05122,647,281 - 122,693,638 (+)NCBI
Rnor_5.05126,507,563 - 126,559,158 (+)NCBI
RGSC_v3.45124,053,388 - 124,100,875 (+)RGD
Celera5116,452,985 - 116,499,350 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238479   ⟹   XP_006238541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,114 - 123,156,653 (+)NCBI
mRatBN7.25117,876,012 - 117,927,592 (+)NCBI
Rnor_6.05122,642,065 - 122,693,638 (+)NCBI
Rnor_5.05126,507,563 - 126,559,158 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593373   ⟹   XP_017448862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,114 - 123,156,653 (+)NCBI
mRatBN7.25117,876,012 - 117,927,592 (+)NCBI
Rnor_6.05122,642,065 - 122,693,638 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593374   ⟹   XP_017448863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,114 - 123,156,653 (+)NCBI
mRatBN7.25117,876,012 - 117,927,592 (+)NCBI
Rnor_6.05122,642,065 - 122,693,638 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593381   ⟹   XP_017448870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,618 - 123,156,653 (+)NCBI
mRatBN7.25117,876,564 - 117,927,592 (+)NCBI
Rnor_6.05122,642,448 - 122,693,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109948   ⟹   XP_038965876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,917 - 123,156,653 (+)NCBI
mRatBN7.25117,876,856 - 117,927,592 (+)NCBI
RefSeq Acc Id: XM_039109951   ⟹   XP_038965879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,917 - 123,156,653 (+)NCBI
mRatBN7.25117,876,854 - 117,927,592 (+)NCBI
RefSeq Acc Id: XM_039109952   ⟹   XP_038965880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,618 - 123,156,653 (+)NCBI
mRatBN7.25117,876,564 - 117,927,592 (+)NCBI
RefSeq Acc Id: XM_039109956   ⟹   XP_038965884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,917 - 123,156,653 (+)NCBI
mRatBN7.25117,876,856 - 117,927,592 (+)NCBI
RefSeq Acc Id: XM_039109957   ⟹   XP_038965885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,606 - 123,156,653 (+)NCBI
mRatBN7.25117,876,564 - 117,927,592 (+)NCBI
RefSeq Acc Id: XM_063287693   ⟹   XP_063143763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,618 - 123,149,513 (+)NCBI
RefSeq Acc Id: XM_063287694   ⟹   XP_063143764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,618 - 123,149,513 (+)NCBI
RefSeq Acc Id: XM_063287695   ⟹   XP_063143765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,917 - 123,156,653 (+)NCBI
RefSeq Acc Id: XM_063287696   ⟹   XP_063143766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,363 - 123,156,653 (+)NCBI
RefSeq Acc Id: XM_063287697   ⟹   XP_063143767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,618 - 123,149,513 (+)NCBI
RefSeq Acc Id: XM_063287698   ⟹   XP_063143768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,114 - 123,149,513 (+)NCBI
RefSeq Acc Id: XM_063287699   ⟹   XP_063143769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,109,317 - 123,156,653 (+)NCBI
RefSeq Acc Id: XM_063287700   ⟹   XP_063143770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,917 - 123,156,653 (+)NCBI
RefSeq Acc Id: XM_063287701   ⟹   XP_063143771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,105,917 - 123,156,653 (+)NCBI
RefSeq Acc Id: XM_063287702   ⟹   XP_063143772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,122,625 - 123,156,653 (+)NCBI
RefSeq Acc Id: XM_063287703   ⟹   XP_063143773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,109,310 - 123,149,513 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001124484 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238541 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448862 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448863 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448870 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965876 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965879 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965880 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965884 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965885 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143763 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143764 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143765 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143766 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143767 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143768 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143769 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143770 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143771 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143772 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143773 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68252 (Get FASTA)   NCBI Sequence Viewer  
  EDL97866 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063001
  ENSRNOP00000063001.1
  ENSRNOP00000081443.1
  ENSRNOP00000083378.1
  ENSRNOP00000085059
  ENSRNOP00000085059.1
RefSeq Acc Id: NP_001124484   ⟸   NM_001131012
- UniProtKB: B4F7F2 (UniProtKB/TrEMBL),   E9PT68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238541   ⟸   XM_006238479
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZWG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448862   ⟸   XM_017593373
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448863   ⟸   XM_017593374
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A0V9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448870   ⟸   XM_017593381
- Peptide Label: isoform X1
- UniProtKB: E9PT68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063001   ⟸   ENSRNOT00000066041
RefSeq Acc Id: ENSRNOP00000075308   ⟸   ENSRNOT00000086765
RefSeq Acc Id: XP_038965880   ⟸   XM_039109952
- Peptide Label: isoform X3
- UniProtKB: E9PT68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965885   ⟸   XM_039109957
- Peptide Label: isoform X5
- UniProtKB: E9PT68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965879   ⟸   XM_039109951
- Peptide Label: isoform X9
- UniProtKB: E9PT68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965876   ⟸   XM_039109948
- Peptide Label: isoform X1
- UniProtKB: E9PT68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965884   ⟸   XM_039109956
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZSL3 (UniProtKB/TrEMBL),   A6JRS4 (UniProtKB/TrEMBL),   E9PT68 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000083378   ⟸   ENSRNOT00000108735
RefSeq Acc Id: ENSRNOP00000081443   ⟸   ENSRNOT00000099770
RefSeq Acc Id: ENSRNOP00000085059   ⟸   ENSRNOT00000095676
RefSeq Acc Id: XP_063143768   ⟸   XM_063287698
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063143766   ⟸   XM_063287696
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063143763   ⟸   XM_063287693
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063143764   ⟸   XM_063287694
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063143767   ⟸   XM_063287697
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063143765   ⟸   XM_063287695
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063143771   ⟸   XM_063287701
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063143770   ⟸   XM_063287700
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063143773   ⟸   XM_063287703
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063143769   ⟸   XM_063287699
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063143772   ⟸   XM_063287702
- Peptide Label: isoform X16
Protein Domains
ELM2   SANT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KA91-F1-model_v2 AlphaFold A0A0G2KA91 1-661 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693865
Promoter ID:EPDNEW_R4390
Type:multiple initiation site
Name:Mier1_1
Description:MIER1 transcriptional regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05122,647,274 - 122,647,334EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562337 AgrOrtholog
BioCyc Gene G2FUF-40508 BioCyc
Ensembl Genes ENSRNOG00000007175 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066041 ENTREZGENE
  ENSRNOT00000066041.2 UniProtKB/TrEMBL
  ENSRNOT00000095676.1 UniProtKB/TrEMBL
  ENSRNOT00000099770.1 UniProtKB/TrEMBL
  ENSRNOT00000108735.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro ELM2_dom UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  MIER/MTA UniProtKB/TrEMBL
  MIER1/3_C UniProtKB/TrEMBL
  SANT_DNA-bd UniProtKB/TrEMBL
  SANT_eukarya UniProtKB/TrEMBL
KEGG Report rno:313418 UniProtKB/TrEMBL
NCBI Gene 313418 ENTREZGENE
PANTHER PTHR10865 UniProtKB/TrEMBL
  PTHR10865:SF24 UniProtKB/TrEMBL
Pfam ELM2 UniProtKB/TrEMBL
  MIER1_beta_C UniProtKB/TrEMBL
  Myb_DNA-binding UniProtKB/TrEMBL
PhenoGen Mier1 PhenoGen
PROSITE ELM2 UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007175 RatGTEx
SMART ELM2 UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A8I5ZSL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWG7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0V9 ENTREZGENE, UniProtKB/TrEMBL
  A6JRS4 ENTREZGENE, UniProtKB/TrEMBL
  B4F7F2 ENTREZGENE, UniProtKB/TrEMBL
  E9PT68 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-15 Mier1  MIER1 transcriptional regulator  Mier1  mesoderm induction early response 1, transcriptional regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-14 Mier1  mesoderm induction early response 1, transcriptional regulator  Mier1  mesoderm induction early response 1 homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Mier1  mesoderm induction early response 1 homolog (Xenopus laevis)  RGD1562337_predicted  similar to mesoderm induction early response 1 (MI-ER1) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562337_predicted  similar to mesoderm induction early response 1 (MI-ER1) (predicted)  LOC313418  similar to mesoderm induction early response 1 (MI-ER1)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC313418  similar to mesoderm induction early response 1 (MI-ER1)      Symbol and Name status set to provisional 70820 PROVISIONAL