Aadacl2fm2 (AADACL2 family member 2)

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Gene: Aadacl2fm2 (AADACL2 family member 2) Rattus norvegicus

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Symbol:

Aadacl2fm2 (Ensembl: RGD1561998)

Name:

AADACL2 family member 2

RGD ID:

1561998

Description:

Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in endoplasmic reticulum and membrane; INTERACTS WITH tributylstannane; titanium dioxide (ortholog).

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

arylacetamide deacetylase-like 2; LOC502533; RGD1561998; similar to hypothetical protein C130079G13

RGD Orthologs

Mouse

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Aadacl2fm2 (AADACL2 family member 2)	RGD	RGD
Other homologs ²
Homo sapiens (human):	AADAC (arylacetamide deacetylase)	HGNC	OrthoDB
Homo sapiens (human):	AADACL2 (arylacetamide deacetylase like 2)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Aadacl2fm2 (AADACL2 family member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	aadac (arylacetamide deacetylase)	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	nceh-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	trcs-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T09B9.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	aadac	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	146,033,047 - 146,061,074 (+)	NCBI		GRCr8
mRatBN7.2	2	143,883,313 - 143,910,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	143,883,265 - 143,911,452 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	149,843,238 - 149,871,729 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	149,843,282 - 149,871,788 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	169,274,770 - 169,302,283 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	149,064,731 - 149,091,866 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	138,306,371 - 138,334,196 (+)	NCBI		Celera
Cytogenetic Map	2	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

titanium dioxide (ISO)

tributylstannane (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

endoplasmic reticulum (IEA)

membrane (IEA)

Molecular Function

carboxylic ester hydrolase activity (IEA)

hydrolase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Aadacl2fm2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	146,033,047 - 146,061,074 (+)	NCBI		GRCr8
mRatBN7.2	2	143,883,313 - 143,910,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	143,883,265 - 143,911,452 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	149,843,238 - 149,871,729 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	149,843,282 - 149,871,788 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	169,274,770 - 169,302,283 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	149,064,731 - 149,091,866 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	138,306,371 - 138,334,196 (+)	NCBI		Celera
Cytogenetic Map	2	q26	NCBI

Aadacl2fm2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	59,637,207 - 59,659,818 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	59,637,211 - 59,659,754 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	59,729,786 - 59,752,397 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	59,729,790 - 59,752,333 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	59,533,708 - 59,556,319 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	59,817,716 - 59,840,262 (+)	NCBI		MGSCv36	mm8
Celera	3	59,405,073 - 59,427,411 (+)	NCBI		Celera
Cytogenetic Map	3	D	NCBI
cM Map	3	29.07	NCBI

Variants

Variants in Aadacl2fm2
84 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	24
Count of miRNA genes:	22
Interacting mature miRNAs:	23
Transcripts:	ENSRNOT00000074805
Prediction methods:	Microtar, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
2293671	Bss44	Bone structure and strength QTL 44	10.97	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	2	43162366	148478373	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	102803808	147803808	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
6907363	Bp357	Blood pressure QTL 357	4.1	0.002	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	129540907	174540907	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1358360	Sradr2	Stress Responsive Adrenal Weight QTL 2	10.24		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	2	129164097	152195315	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
1549828	Bp258	Blood pressure QTL 258		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	142323368	150650069	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	76539322	150540526	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	143657411	190602963	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
12879844	Kidm62	Kidney mass QTL 62		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	142323368	146786035	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	114837527	185876470	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
12879841	Cm87	Cardiac mass QTL 87		0.026	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	142323368	146786035	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
12879842	Cm88	Cardiac mass QTL 88		0.042	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	142323368	146786035	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
12879843	Am3	Aortic mass QTL 3		0.016	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	142323368	146786035	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1582257	Gluco21	Glucose level QTL 21	3.1	0.0035	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	118111229	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
8662836	Vetf8	Vascular elastic tissue fragility QTL 8	0.66		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	104559726	149559726	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
5135226	Leukc2	Leukocyte quantity QTL 2			eosinophil quantity (VT:0002602)	blood eosinophil count (CMO:0000033)	2	118111229	149559726	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
7488933	Bp368	Blood pressure QTL 368		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	142323368	147803808	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
738007	Anxrr7	Anxiety related response QTL 7	4.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	118189491	163189491	Rat
9685068	Swd7	Spike wave discharge measurement QTL 7	3.2	0.01	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge rate (CMO:0001739)	2	141656606	147588984	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	157142209	Rat
1581552	Pur12	Proteinuria QTL 12	5.19	0.0009	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	2	112103657	148076632	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
1558653	Prcr1	Prostate cancer resistance QTL 1	5		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	2	72532993	157142209	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
1354594	Despr10	Despair related QTL 10		2e-06	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	2	114654253	159654253	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
6903312	Bw112	Body weight QTL 112	3.2	0.0013	body mass (VT:0001259)	body weight (CMO:0000012)	2	143657569	184114274	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

ectoderm	endocrine system	endoderm	exocrine system	hepatobiliary system	integumental system	mesenchyme	nervous system	renal system	reproductive system
12	5	1	1	1	6	8	6	7	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001061963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_578019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000074805 ⟹ ENSRNOP00000064464

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	143,883,265 - 143,911,452 (+)	Ensembl
Rnor_6.0 Ensembl	2	149,843,282 - 149,871,788 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109831 ⟹ ENSRNOP00000087952

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	143,896,981 - 143,911,452 (+)	Ensembl

RefSeq Acc Id:

XM_063282766 ⟹ XP_063138836

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	146,033,047 - 146,060,796 (+)	NCBI

RefSeq Acc Id:

XM_578019 ⟹ XP_578019

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	146,033,047 - 146,061,074 (+)	NCBI
mRatBN7.2	2	143,883,313 - 143,910,452 (+)	NCBI
Rnor_6.0	2	149,843,238 - 149,871,729 (+)	NCBI
Rnor_5.0	2	169,274,770 - 169,302,283 (+)	NCBI
RGSC_v3.4	2	149,064,731 - 149,091,866 (+)	RGD

Sequence:

show sequence

GAGTTCACTTAAGCCCTTTGACTTAATATTTAGTAGTCAGTATGTAGGATGACACTCCTCATTG
CACAGAAGTAAAGAAAGATACATGGGATACATGGGATACAAAACTCTGTGCTTCGGGTTGTTCC
TTATTCTCTTTGCTTATTATAGTTATATACCAATGCCTGAAAACATTGAAGAACGCTGGAAAAT
TCAGTTTCTGGATGCTGGTATGAAAATGTTGTCATTTATGGCCAAAATGTTTGAAAACTTGGGT
CTTATAAAATATGAAGATGTTTTGTCTATATTTATGAGAGTGCTTCTGACAAAACCAGTTTCAG
ATGAAAACATTACAGTGATTGACACAGACTTCAGTGACATCCCTGTTCGTCTGTATTTACCCAA
ATGGAAGTCTGAAAGACAGCGACCAGCTGTGATTTACATTCATGGTGGTGCCTTCACCTTAGGA
AGCTGCAAGATACGCTCCTATGATTACCTGAACCGATGGACAGCAAACAAGCTTGATGCTGTTG
TTGTGGGACTAGACTACAGGCTTGCTCCTCAGTATCCATTCCCAACTGCCTTTGAAGATTGTGT
TCTTGTGATCAAGTTCTTTCTCCAGGACACAATTCTTGAAAAGTATGGAGTAGATCCCACTCGC
ATTTGTATTTCTGGAGACAGCTCTGGAGGCTCATTGGCAACAGCAGCAACTCAGTTGCTCCAGA
ATAATCCAGAATATAAAGATAAAATTAAGGCACAAGCCTTGATATATCCTGCACTACAATTTAT
CGACACCTTGATGCCATCTCATCGAGAGTATGAACATGGTCCCTTTCTTTCAAGAGAGATAGGA
ATTAAGCTGGCACACCTATATGTAACTGAAGACATAGCCCTGCACCAGGCTATGCAGAGAAATG
AACACATGCCTCAAGGATCAAGACACCTGTTCAAGTTTGTTAACTGGAGTGACTTTCTTCCTGA
GAAGTATAAAAAGAACCATGTTTATAATGAGCCCACTCTTGGAAAGCTAAATGTATTCTACCCA
GCACTTATGGATAGCAGGCTATCTCCTTTGCTAGCCAGTGACTCTCAGTTACAGAGTTTGCCAT
TAACATACATCCTCACTTGTGAACATGATGTCCTAAGAGATGAGGGTCTCATTTATATTACACG
TCTTAGAAATGTTGGGGTTCAAGTTGCTCATGACCACATAGAAGAAGGGATCCATGGAGTCATG
TCACTCATTGCAATGCCATACAATTTACAGTTAGGATTAAAAGTAGGAGAAAAATATATCAGTT
GGTTAGAAAAAAACTTATAAATCAAGCATAGATGGAGATAATTTAATCTAATGTTTAGTAAGCA
TGATGATAATTTGAGTTGTATTTGAACATACATATAATTTAGCATAAAGATCTTTGCACAAATT
TGATAAATATACTTAAATATCCTGTTTGTTACTGAAAATGTGGAGTATTCACTTATTATTCCCA
TTACTATCATGTATTATCTTGTGACGGAAAGTCTCTAAGAATTCAATTGTAGTAGTTCAGCATT
AAAATGTGGTTATATGCAAAAACACATGTCTGTTCCCAGACCATGATAAAAACCAAGTGATGGA
GACAAAACAGTTGTATTGAGTGAACACTATTTAGTATTTCTGGCAAAGTTTCCAATTATATATT
TATACATTAATTCCATATGCTCAATATAAGTTAAATCCATTTTTTAGTTTATGTTTTTGGAAGT
TTATGTATACTCTGAATAGAAAGCTTTCCTTTATTGTGGAGAAGCTTAACATCTAAACTGAAAA
TATTTCCTGTAGTTTAAATATGTCATCTTTATTTATAATTTAGTAAAAGCAAACTTGAAGATAA
CTGTCTGAACAGCATCCATTGCTAACCAATGATTCTTAATCCTTGATGACATAGAAACAAGTAT
AGATAGCAGTTAGAATTATTCATTCTGCTTTTCTTAATTTTCAAAGTGAGTCATTAGCAAACGT
GGAGACTATTCACCTAGGAAGTTATATAAGCTCCAATCTATTTGCTTCCCTCTTTGATGAGACC
AACACACTCATCAGCTCACAACTGCATAATAACCAATTTTCATTTTCTTTGGGAGGTATTAAAA
TTATATAATTTCTGAGATACAAATGAGTATGCTGTTTGCACATGGCTGCTTTTACCTGAGATGA
TCTTTATC

hide sequence

Protein Sequences


Protein RefSeqs	XP_063138836	(Get FASTA)	NCBI Sequence Viewer
	XP_578019	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064464.2
	ENSRNOP00000087952.1

RefSeq Acc Id:	XP_578019 ⟸ XM_578019
- Peptide Label:	isoform X1
- UniProtKB:	M0R509 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGYMGYKTLCFGLFLILFAYYSYIPMPENIEERWKIQFLDAGMKMLSFMAKMFENLGLIKYEDV LSIFMRVLLTKPVSDENITVIDTDFSDIPVRLYLPKWKSERQRPAVIYIHGGAFTLGSCKIRSY DYLNRWTANKLDAVVVGLDYRLAPQYPFPTAFEDCVLVIKFFLQDTILEKYGVDPTRICISGDS SGGSLATAATQLLQNNPEYKDKIKAQALIYPALQFIDTLMPSHREYEHGPFLSREIGIKLAHLY VTEDIALHQAMQRNEHMPQGSRHLFKFVNWSDFLPEKYKKNHVYNEPTLGKLNVFYPALMDSRL SPLLASDSQLQSLPLTYILTCEHDVLRDEGLIYITRLRNVGVQVAHDHIEEGIHGVMSLIAMPY NLQLGLKVGEKYISWLEKNL hide sequence

Ensembl Acc Id:

ENSRNOP00000064464 ⟸ ENSRNOT00000074805

Ensembl Acc Id:

ENSRNOP00000087952 ⟸ ENSRNOT00000109831

RefSeq Acc Id:	XP_063138836 ⟸ XM_063282766
- Peptide Label:	isoform X2

Protein Domains

Alpha/beta hydrolase fold-3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0R509-F1-model_v2	AlphaFold	M0R509	1-404	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691353

Promoter ID:

EPDNEW_R1876

Type:

single initiation site

Name:

RGD1561998_1

Description:

similar to hypothetical protein C130079G13

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	149,843,291 - 149,843,351	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561998	AgrOrtholog
BioCyc Gene	G2FUF-52981	BioCyc
Ensembl Genes	ENSRNOG00000048440	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000074805.3	UniProtKB/TrEMBL
	ENSRNOT00000109831.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	AB_hydrolase_3	UniProtKB/TrEMBL
	Arylacetamide_deacetylase	UniProtKB/TrEMBL
	Carboxylest/Gibb_receptor	UniProtKB/TrEMBL
	GDXG_lipolytic_enzyme	UniProtKB/TrEMBL
	Lipase_GDXG_put_SER_AS	UniProtKB/TrEMBL
KEGG Report	rno:502533	UniProtKB/TrEMBL
NCBI Gene	502533	ENTREZGENE
PANTHER	AADACL2 FAMILY MEMBER 2-RELATED	UniProtKB/TrEMBL
	AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C	UniProtKB/TrEMBL
	ARYLACETAMIDE DEACETYLASE	UniProtKB/TrEMBL
	SIMILAR TO HYPOTHETICAL PROTEIN C130079G13	UniProtKB/TrEMBL
Pfam	Abhydrolase_3	UniProtKB/TrEMBL
PhenoGen	Aadacl2fm2	PhenoGen
PIRSF	Arylacetamide_deacetylase	UniProtKB/TrEMBL
PROSITE	LIPASE_GDXG_SER	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000048440	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	A0A8I6A6X0_RAT	UniProtKB/TrEMBL
	M0R509	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-01-06	Aadacl2fm2	AADACL2 family member 2	RGD1561998	similar to hypothetical protein C130079G13	Name and Symbol changed	629549	APPROVED
2008-04-30	RGD1561998	similar to hypothetical protein C130079G13	RGD1561998_predicted	similar to hypothetical protein C130079G13 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1561998_predicted	similar to hypothetical protein C130079G13 (predicted)	LOC502533	similar to hypothetical protein C130079G13	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC502533	similar to hypothetical protein C130079G13			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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