RGD1561560 (similar to Gpd1l protein) - Rat Genome Database

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Gene: RGD1561560 (similar to Gpd1l protein) Rattus norvegicus
Analyze
Symbol: RGD1561560 (Ensembl: AC099360.1)
Name: similar to Gpd1l protein
RGD ID: 1561560
Description: Predicted to enable NAD binding activity; glycerol-3-phosphate dehydrogenase [NAD(P)+] activity; and protein homodimerization activity. Predicted to be involved in carbohydrate metabolic process and glycerol-3-phosphate catabolic process. Predicted to be part of glycerol-3-phosphate dehydrogenase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC502711
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2410,523,777 - 10,527,072 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,522,914 - 10,527,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,669,845 - 15,673,125 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,490,038 - 11,493,318 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,841,822 - 9,845,102 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.047,051,780 - 7,055,113 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.047,064,287 - 7,067,602 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,903,245 - 5,906,528 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera46,139,723 - 6,143,056 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in RGD1561560
3 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000032728   ⟹   ENSRNOP00000095672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,522,914 - 10,527,084 (-)Ensembl
RefSeq Acc Id: NM_001346361   ⟹   NP_001333290
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2410,523,777 - 10,527,057 (-)NCBI
RefSeq Acc Id: NM_001346362   ⟹   NP_001333291
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2410,523,777 - 10,527,057 (-)NCBI
RefSeq Acc Id: XM_039108237   ⟹   XP_038964165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2410,523,777 - 10,527,072 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001333290 (Get FASTA)   NCBI Sequence Viewer  
  NP_001333291 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964165 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL99341 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_038964165   ⟸   XM_039108237
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001333291   ⟸   NM_001346362
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001333290   ⟸   NM_001346361
- Peptide Label: isoform 1
- UniProtKB: A0A8I6ALX9 (UniProtKB/TrEMBL),   A6K532 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000095672   ⟸   ENSRNOT00000032728
Protein Domains
Glycerol-3-phosphate dehydrogenase NAD-dependent C-   Glycerol-3-phosphate dehydrogenase NAD-dependent N-

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-46055 BioCyc
Ensembl Genes ENSRNOG00000025214 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000095672 ENTREZGENE
  ENSRNOP00000095672.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032728 ENTREZGENE
  ENSRNOT00000032728.7 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/TrEMBL
  6PGD_dom2 UniProtKB/TrEMBL
  G3P_DH_NAD-dep UniProtKB/TrEMBL
  G3P_DH_NAD-dep_C UniProtKB/TrEMBL
  G3P_DH_NAD-dep_euk UniProtKB/TrEMBL
  G3P_DH_NAD-dep_N UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
KEGG Report rno:502711 UniProtKB/TrEMBL
NCBI Gene 502711 ENTREZGENE
PANTHER GLYCEROL-3-PHOSPHATE DEHYDROGENASE UniProtKB/TrEMBL
  GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam NAD_Gly3P_dh_C UniProtKB/TrEMBL
  NAD_Gly3P_dh_N UniProtKB/TrEMBL
PhenoGen RGD1561560 PhenoGen
PRINTS GPDHDRGNASE UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A8I6ALX9 ENTREZGENE, UniProtKB/TrEMBL
  A6K532 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 RGD1561560  similar to Gpd1l protein   RGD1561560_predicted  similar to Gpd1l protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561560_predicted  similar to Gpd1l protein (predicted)  LOC502711  similar to Gpd1l protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502711  similar to Gpd1l protein      Symbol and Name status set to provisional 70820 PROVISIONAL