Ercc6l2 (ERCC excision repair 6 like 2) - Rat Genome Database

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Gene: Ercc6l2 (ERCC excision repair 6 like 2) Rattus norvegicus
Analyze
Symbol: Ercc6l2
Name: ERCC excision repair 6 like 2
RGD ID: 1561537
Description: Predicted to enable protein kinase binding activity. Predicted to be involved in cellular response to reactive oxygen species and interstrand cross-link repair. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to colocalize with centrosome. Orthologous to human ERCC6L2 (ERCC excision repair 6 like 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA excision repair protein ERCC-6-like 2; excision repair cross-complementation group 6-like 2; excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2; LOC361197; putative DNA repair and recombination protein RAD26-like; RGD1561537; similar to putative repair and recombination helicase RAD26L
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2171,076,486 - 1,311,281 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl171,216,428 - 1,310,275 (-)Ensembl
Rnor_6.0171,325,654 - 1,421,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,305,016 - 1,421,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,318,508 - 1,414,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,747,582 - 6,845,232 (-)NCBIRGSC3.4rn4RGSC3.4
Celera171,207,807 - 1,301,350 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:20873783   PMID:24507776  


Genomics

Comparative Map Data
Ercc6l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2171,076,486 - 1,311,281 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl171,216,428 - 1,310,275 (-)Ensembl
Rnor_6.0171,325,654 - 1,421,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,305,016 - 1,421,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,318,508 - 1,414,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,747,582 - 6,845,232 (-)NCBIRGSC3.4rn4RGSC3.4
Celera171,207,807 - 1,301,350 (+)NCBICelera
Cytogenetic Map17p14NCBI
ERCC6L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38995,875,691 - 96,041,092 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl995,871,264 - 96,121,154 (+)EnsemblGRCh38hg38GRCh38
GRCh37998,637,973 - 98,803,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36997,677,721 - 97,770,943 (+)NCBINCBI36hg18NCBI36
Celera969,079,501 - 69,172,730 (+)NCBI
Cytogenetic Map9q22.32NCBI
HuRef968,248,993 - 68,342,217 (+)NCBIHuRef
CHM1_1998,784,502 - 98,877,688 (+)NCBICHM1_1
T2T-CHM13v2.09108,047,061 - 108,212,474 (+)NCBI
Ercc6l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391363,958,793 - 64,048,116 (+)NCBIGRCm39mm39
GRCm39 Ensembl1363,963,054 - 64,048,116 (+)Ensembl
GRCm381363,810,979 - 63,900,302 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1363,815,240 - 63,900,302 (+)EnsemblGRCm38mm10GRCm38
MGSCv371363,916,628 - 64,001,610 (+)NCBIGRCm37mm9NCBIm37
MGSCv361363,973,763 - 64,001,610 (+)NCBImm8
Celera1365,468,731 - 65,557,796 (+)NCBICelera
Cytogenetic Map13B3NCBI
Ercc6l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542222,753,233 - 22,879,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542222,753,008 - 22,890,339 (+)NCBIChiLan1.0ChiLan1.0
ERCC6L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1995,091,344 - 95,230,680 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl995,092,512 - 95,183,122 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0966,967,399 - 67,153,934 (+)NCBIMhudiblu_PPA_v0panPan3
ERCC6L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,793,975 - 70,918,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,835,410 - 70,917,962 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha171,556,932 - 71,681,271 (-)NCBI
ROS_Cfam_1.0171,094,863 - 71,216,795 (-)NCBI
ROS_Cfam_1.0 Ensembl170,970,562 - 71,251,480 (-)Ensembl
UMICH_Zoey_3.1170,905,183 - 71,035,451 (-)NCBI
UNSW_CanFamBas_1.0170,669,817 - 70,792,128 (-)NCBI
UU_Cfam_GSD_1.0171,380,405 - 71,505,183 (-)NCBI
LOC101967543
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049445,816,651 - 5,847,038 (+)NCBI
SpeTri2.0NW_00493648733,082 - 60,819 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERCC6L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1026,112,032 - 26,264,175 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11026,112,019 - 26,264,759 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21030,329,098 - 30,457,306 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERCC6L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112107,095,221 - 107,224,532 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl12107,095,952 - 107,224,197 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603895,450,134 - 95,624,155 (-)NCBIVero_WHO_p1.0
Ercc6l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475317,393,629 - 17,547,793 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH129895  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2171,216,562 - 1,216,747 (-)MAPPERmRatBN7.2
Rnor_6.0171,421,410 - 1,421,594NCBIRnor6.0
Rnor_5.0171,413,833 - 1,414,017UniSTSRnor5.0
RGSC_v3.4176,747,720 - 6,747,904UniSTSRGSC3.4
Celera171,301,028 - 1,301,212UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS
BF389211  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2171,236,880 - 1,237,013 (-)MAPPERmRatBN7.2
Rnor_6.0171,401,144 - 1,401,276NCBIRnor6.0
Rnor_5.0171,393,567 - 1,393,699UniSTSRnor5.0
RGSC_v3.4176,768,038 - 6,768,170UniSTSRGSC3.4
Celera171,280,762 - 1,280,894UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS
BF413745  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2171,291,894 - 1,292,392 (-)MAPPERmRatBN7.2
Rnor_6.0171,343,560 - 1,344,057NCBIRnor6.0
Rnor_5.0171,336,419 - 1,336,916UniSTSRnor5.0
RGSC_v3.4176,826,600 - 6,827,097UniSTSRGSC3.4
Celera171,225,695 - 1,226,192UniSTS
RH 3.4 Map172.4UniSTS
Cytogenetic Map17p14UniSTS
AI233476  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2171,289,882 - 1,289,972 (-)MAPPERmRatBN7.2
Rnor_6.0171,345,980 - 1,346,069NCBIRnor6.0
Rnor_5.0171,338,839 - 1,338,928UniSTSRnor5.0
RGSC_v3.4176,824,588 - 6,824,677UniSTSRGSC3.4
Celera171,228,115 - 1,228,204UniSTS
RH 3.4 Map175.4UniSTS
Cytogenetic Map17p14UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:247
Count of miRNA genes:167
Interacting mature miRNAs:192
Transcripts:ENSRNOT00000025965, ENSRNOT00000026011, ENSRNOT00000035471
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 40 24 19 24 8 8 74 35 37 11 8
Low 7 17 17 17 3 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001400699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000025965   ⟹   ENSRNOP00000025965
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl171,216,428 - 1,310,275 (-)Ensembl
Rnor_6.0 Ensembl171,305,016 - 1,421,685 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112076   ⟹   ENSRNOP00000091193
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl171,291,055 - 1,310,275 (-)Ensembl
RefSeq Acc Id: XM_006253498   ⟹   XP_006253560
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,216,425 - 1,311,281 (-)NCBI
Rnor_6.0171,325,654 - 1,421,732 (+)NCBI
Rnor_5.0171,318,508 - 1,414,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096259   ⟹   XP_038952187
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,216,425 - 1,311,281 (-)NCBI
RefSeq Acc Id: XM_039096260   ⟹   XP_038952188
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,154,379 - 1,311,281 (-)NCBI
RefSeq Acc Id: XM_039096261   ⟹   XP_038952189
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,076,486 - 1,311,281 (-)NCBI
RefSeq Acc Id: XM_039096262   ⟹   XP_038952190
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,216,425 - 1,282,203 (-)NCBI
RefSeq Acc Id: XM_039096263   ⟹   XP_038952191
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,274,467 - 1,311,281 (-)NCBI
RefSeq Acc Id: XR_005495504
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,154,379 - 1,311,281 (-)NCBI
RefSeq Acc Id: XR_005495505
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,221,939 - 1,311,281 (-)NCBI
RefSeq Acc Id: XR_005495506
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2171,221,939 - 1,311,281 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006253560   ⟸   XM_006253498
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000025965   ⟸   ENSRNOT00000025965
RefSeq Acc Id: XP_038952189   ⟸   XM_039096261
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038952188   ⟸   XM_039096260
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038952187   ⟸   XM_039096259
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952190   ⟸   XM_039096262
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038952191   ⟸   XM_039096263
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000091193   ⟸   ENSRNOT00000112076
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZPU4-F1-model_v2 AlphaFold D3ZPU4 1-1532 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
17 1335509 1335510 C G snv WN/N (2020), GH/OmrMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561537 AgrOrtholog
BioCyc Gene G2FUF-10534 BioCyc
Ensembl Genes ENSRNOG00000019175 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025965 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025965 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD-like_N UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  Heliccase-ass_bd UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  Tudor UniProtKB/TrEMBL
NCBI Gene 361197 ENTREZGENE
Pfam Helicase_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  VIGSSK UniProtKB/TrEMBL
PhenoGen Ercc6l2 PhenoGen
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt D3ZPU4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Ercc6l2  ERCC excision repair 6 like 2  Ercc6l2  excision repair cross-complementation group 6-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-03-12 Ercc6l2  excision repair cross-complementation group 6-like 2  Ercc6l2  excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-11 Ercc6l2  excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2  RGD1561537  similar to putative repair and recombination helicase RAD26L  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561537  similar to putative repair and recombination helicase RAD26L   RGD1561537_predicted  similar to putative repair and recombination helicase RAD26L (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561537_predicted  similar to putative repair and recombination helicase RAD26L (predicted)  LOC361197  similar to putative repair and recombination helicase RAD26L  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC361197  similar to putative repair and recombination helicase RAD26L      Symbol and Name status set to provisional 70820 PROVISIONAL