Cdx4 (caudal type homeo box 4) - Rat Genome Database

Name: Cdx4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Cdx4 (caudal type homeo box 4) Rattus norvegicus

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Symbol:

Cdx4

Name:

caudal type homeo box 4

RGD ID:

1561529

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including animal organ morphogenesis; anterior/posterior axis specification; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including blood vessel development; labyrinthine layer development; and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human CDX4 (caudal type homeobox 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; (+)-catechin (ortholog).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

homeobox protein CDX-4; LOC302400; RGD1561529; similar to homeobox protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDX4 (caudal type homeobox 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cdx4 (caudal type homeobox 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDX4 (caudal type homeobox 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDX4 (caudal type homeobox 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdx4 (caudal type homeobox 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDX4 (caudal type homeobox 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDX4 (caudal type homeobox 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CDX4 (caudal type homeobox 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cdx4 (caudal type homeobox 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cdx4 (caudal type homeobox 4)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	cad	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pal-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cdx4	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	72,392,653 - 72,401,239 (+)	NCBI		GRCr8
mRatBN7.2	X	68,326,874 - 68,335,461 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	68,326,874 - 68,335,461 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	69,836,078 - 69,844,664 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	73,336,321 - 73,344,907 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	70,897,507 - 70,906,094 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	74,165,172 - 74,173,758 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	74,165,187 - 74,173,347 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	74,973,425 - 74,982,011 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	91,285,627 - 91,294,213 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	69,694,561 - 69,703,147 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(R)-lipoic acid (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

aflatoxin B1 (ISO)

arsenite(3-) (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carmustine (ISO)

CGP 52608 (ISO)

fulvestrant (ISO)

lipoic acid (ISO)

nickel atom (ISO)

phenobarbital (ISO)

potassium dichromate (ISO)

rotenone (ISO)

sodium arsenite (ISO)

trichostatin A (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ morphogenesis (IBA)

anterior/posterior axis specification (IBA)

anterior/posterior pattern specification (ISO)

blood vessel development (ISO)

cell differentiation (IBA)

labyrinthine layer development (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

placenta development (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IBA)

Molecular Function

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16325584	PMID:16396910	PMID:19853565	PMID:21471217

Genomics

Comparative Map Data

Cdx4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	72,392,653 - 72,401,239 (+)	NCBI		GRCr8
mRatBN7.2	X	68,326,874 - 68,335,461 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	68,326,874 - 68,335,461 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	69,836,078 - 69,844,664 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	73,336,321 - 73,344,907 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	70,897,507 - 70,906,094 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	74,165,172 - 74,173,758 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	74,165,187 - 74,173,347 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	74,973,425 - 74,982,011 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	91,285,627 - 91,294,213 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	69,694,561 - 69,703,147 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

CDX4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	73,447,053 - 73,455,171 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	73,447,053 - 73,455,171 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	72,666,889 - 72,675,007 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	72,583,815 - 72,591,146 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	72,450,110 - 72,457,442	NCBI
Celera	X	72,950,582 - 72,957,913 (+)	NCBI		Celera
Cytogenetic Map	X	q13.2	NCBI
HuRef	X	66,300,313 - 66,307,741 (+)	NCBI		HuRef
CHM1_1	X	72,559,663 - 72,566,994 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	71,880,436 - 71,888,553 (+)	NCBI		T2T-CHM13v2.0

Cdx4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	102,365,004 - 102,373,830 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	102,365,004 - 102,374,198 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	103,321,398 - 103,330,224 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	103,321,398 - 103,330,592 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	100,516,737 - 100,525,563 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	99,524,117 - 99,532,943 (+)	NCBI		MGSCv36	mm8
Celera	X	90,224,804 - 90,233,630 (+)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	46.06	NCBI

CDX4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	73,104,609 - 73,112,724 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	73,108,217 - 73,116,332 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	62,674,244 - 62,681,944 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	72,796,815 - 72,804,511 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	72,796,634 - 72,804,717 (+)	Ensembl	panpan1.1		panPan2

CDX4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	57,123,670 - 57,135,557 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	57,123,920 - 57,135,089 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	48,300,603 - 48,312,019 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	58,333,869 - 58,345,353 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	58,334,119 - 58,345,353 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	56,080,880 - 56,092,285 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	57,658,854 - 57,670,267 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	57,244,945 - 57,256,373 (+)	NCBI		UU_Cfam_GSD_1.0

Cdx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	44,641,717 - 44,650,841 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936683	297,112 - 305,506 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936683	297,112 - 305,506 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDX4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	59,091,946 - 59,100,431 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	59,089,131 - 59,100,958 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	66,967,157 - 66,975,586 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDX4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	63,013,317 - 63,022,748 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	63,014,049 - 63,021,422 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	4,956,143 - 4,964,303 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Cdx4
3 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	327
Count of miRNA genes:	200
Interacting mature miRNAs:	236
Transcripts:	ENSRNOT00000003973
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	ectoderm	endocrine system	endoderm	exocrine system	hepatobiliary system	mesenchyme	nervous system	renal system	reproductive system	respiratory system
8	2	26	31	22	22	59	2	29	12	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000003973 ⟹ ENSRNOP00000003973

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	68,326,874 - 68,335,461 (+)	Ensembl
Rnor_6.0 Ensembl	X	74,165,187 - 74,173,347 (+)	Ensembl

RefSeq Acc Id:

NM_001106942 ⟹ NP_001100412

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	72,392,653 - 72,401,239 (+)	NCBI
mRatBN7.2	X	68,326,874 - 68,335,461 (+)	NCBI
Rnor_6.0	X	74,165,172 - 74,173,758 (+)	NCBI
Rnor_5.0	X	74,973,425 - 74,982,011 (+)	NCBI
RGSC_v3.4	X	91,285,627 - 91,294,213 (+)	RGD
Celera	X	69,694,561 - 69,703,147 (+)	RGD

Sequence:

show sequence

TTAGGGTAGGATAGGAAGGTTGGAGTAGTCCGAGCCGCCCAGAGGAGCTGGCAGCACAGCGAGT
GCTGACCCATTCATTGATAGCCTCTTGCATCTCAAACTCGGGTTGGCGCTAAGTTTACAGGGTC
CTCAGGATGGCTTAGGGGGCAACTTCTTCTATCCAAGCCACCATGTATGGAAGCTGCCTTTTAG
AAAAAGAAGCGGGAATGTACCCAGGCACTCTCAGGAACCCTGGAGGAGGCAGCACAGCCGGAGT
GGGCACCTCTGGGGGCAGTGGTAGTCCTCTGCCTGCCTCCAACTTTACTGCAGCCCCAGTTTAC
CCACACTACATGGGGTATCCACATATGTCCAACATGGATCCTCACGGGCCTTCGCTGGGAGCCT
GGAGCTCACCCTACAGTCCGCCCCGGGAAGACTGGAGTACATACCCTGGGCCGTCCAGCACAAT
GGGCACAGTGCCCATGAACGACATGACCTCGAGCTCCCCAGCTTTCGGCTCCCCAGACTACAGC
ACTCTGGGCCCCACTGGCGGTGCAGGCGGTGCAAGCAACGGCGGTAGCCTGCCAGACGCGGCCA
GCGAGTCACTGGTTTCCATCGACTCAGGCACCTCTGGCGGCGCCACTTCTCCCAGCAGGAGCCG
CCACAGCCCCTACGCGTGGATGCGCAAGACTGTGCAGGTGACCGGGAAAACCAGGACAAAAGAA
AAGTATCGTGTGGTCTACACGGATCATCAAAGGCTGGAGCTGGAAAAGGAATTTCACTGCAATA
GATACATTACCATCCGGAGGAAGTCAGAGCTGGCAGTTAACCTGGGCCTTTCTGAGAGACAGGT
GAAAATCTGGTTTCAGAATCGCAGAGCCAAGGAGAGGAAGATGATCAAAAAGAAAATCTCCCAG
TTTGAGAACAGTGGAGGTTCCGTGCAAAGTGACTCTGGCTCCATCAGCCCCGGAGAACTGCCTA
ATGCTTTCTTCACCACTCCATCTGCTGTCCGTGGGTTTCAGCCAATTGAGATACAGCAGGTCAT
AATTTCTGAATGAAACGGGAGCAGAGAAACCAACGCATCCTTCCTGTTACAGTGTCTCTTTGGC
CTCTAAGATAACAGCAGGGCAGTTGAGATCGGATATACTTCCTTATAAGGCACAATTCCAAACA
AGTAGACACACCATGAGTTGGAGATATTTCAGAAGACTCTAATATTAAGAAAAATCTTATTTCA
TGCTGTCAAATGGGCACTGGGCAGAAAGCTGTGCGATACGTTTTTCTACTTAAAGTCTAGATTC
AAGAGCCCTTGAAACTTTGTTTACAATTTCAGAAACTCATTTGTTCCTATGCTCTTGTGTTTGT
TATTTGATTCTGAGTATCTTCCTGGTCTTTTTAGGGGATAGGAGTAAGGTAAGCATACATTTCT
CTATCTGGAGACATTGTTTGGAGGGAGTAATTAAAAAACCACCAGTCTTTTTAACAAGCTAACT
GTGTAAAACAGCATCAAGAAGTGATTACGAATCTATTGGTTAATTACATGAAGATCACTTTTCC
CTTTGAATAATACTCACTTACCATCAATTACCTGGTCATAGAATTTAGAAGATTTATTTCAAAT
CGTGTCAAAACAATG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100412	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07192	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003973.2

RefSeq Acc Id:

NP_001100412 ⟸ NM_001106942

- UniProtKB:

D3ZF67 (UniProtKB/TrEMBL), A6IUY8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYGSCLLEKEAGMYPGTLRNPGGGSTAGVGTSGGSGSPLPASNFTAAPVYPHYMGYPHMSNMDP
HGPSLGAWSSPYSPPREDWSTYPGPSSTMGTVPMNDMTSSSPAFGSPDYSTLGPTGGAGGASNG
GSLPDAASESLVSIDSGTSGGATSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLEL
EKEFHCNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKISQFENSGGSVQSDSGS
ISPGELPNAFFTTPSAVRGFQPIEIQQVIISE

hide sequence

Ensembl Acc Id:

ENSRNOP00000003973 ⟸ ENSRNOT00000003973

Protein Domains

Homeobox

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZF67-F1-model_v2	AlphaFold	D3ZF67	1-288	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561529	AgrOrtholog
BioCyc Gene	G2FUF-2031	BioCyc
Ensembl Genes	ENSRNOG00000002974	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000003973.5	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Caudal_activation_dom	UniProtKB/TrEMBL
	Caudal_homeobox	UniProtKB/TrEMBL
	Homeobox	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_region	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	HTH_lambrepressr	UniProtKB/TrEMBL
KEGG Report	rno:302400	UniProtKB/TrEMBL
NCBI Gene	302400	ENTREZGENE
PANTHER	HOMEOBOX PROTEIN CDX	UniProtKB/TrEMBL
	HOMEOBOX PROTEIN CDX-4	UniProtKB/TrEMBL
Pfam	Caudal_act	UniProtKB/TrEMBL
	Homeobox	UniProtKB/TrEMBL
PhenoGen	Cdx4	PhenoGen
PRINTS	HOMEOBOX	UniProtKB/TrEMBL
	HTHREPRESSR	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002974	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	A6IUY8	ENTREZGENE, UniProtKB/TrEMBL
	D3ZF67	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Cdx4	caudal type homeo box 4	Cdx4_predicted	caudal type homeo box 4 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Cdx4_predicted	caudal type homeo box 4 (predicted)	RGD1561529_predicted	similar to homeobox protein (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1561529_predicted	similar to homeobox protein (predicted)	LOC302400	similar to homeobox protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC302400	similar to homeobox protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar