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Gene: Nemp2 (nuclear envelope integral membrane protein 2) Rattus norvegicus

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Symbol:

Nemp2

Name:

nuclear envelope integral membrane protein 2

RGD ID:

1560421

Description:

Predicted to be located in nuclear inner membrane. Predicted to be active in nuclear envelope. Orthologous to human NEMP2 (nuclear envelope integral membrane protein 2); INTERACTS WITH acetamide; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC503257; LOC685327; RGD1560421; similar to Protein KIAA0286; similar to RIKEN cDNA 5330401P04; Tmem194b; transmembrane protein 194B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	56,353,233 - 56,372,586 (-)	NCBI		GRCr8
mRatBN7.2	9	48,861,252 - 48,880,565 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	48,861,252 - 48,880,512 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	57,403,304 - 57,422,604 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	62,526,134 - 62,545,434 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	60,822,129 - 60,841,431 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	53,713,598 - 53,732,858 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	53,713,598 - 53,732,858 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	53,380,915 - 53,400,175 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	45,848,645 - 45,867,905 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	46,529,998 - 46,549,258 (-)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

immunodeficiency 31B (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

3,3',5,5'-tetrabromobisphenol A (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

bisphenol A (EXP)

butanal (ISO)

C60 fullerene (EXP)

carbon nanotube (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

gentamycin (EXP)

leflunomide (ISO)

paracetamol (EXP,ISO)

sodium arsenite (ISO)

tetraphene (ISO)

thioacetamide (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

nuclear envelope (IBA)

nuclear inner membrane (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Nemp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	56,353,233 - 56,372,586 (-)	NCBI		GRCr8
mRatBN7.2	9	48,861,252 - 48,880,565 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	48,861,252 - 48,880,512 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	57,403,304 - 57,422,604 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	62,526,134 - 62,545,434 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	60,822,129 - 60,841,431 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	53,713,598 - 53,732,858 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	53,713,598 - 53,732,858 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	53,380,915 - 53,400,175 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	45,848,645 - 45,867,905 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	46,529,998 - 46,549,258 (-)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

NEMP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	190,421,421 - 190,648,785 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	190,504,338 - 190,534,722 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	191,369,064 - 191,399,448 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	191,077,313 - 191,108,164 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	184,966,557 - 184,994,411 (-)	NCBI		Celera
Cytogenetic Map	2	q32.2	NCBI
HuRef	2	183,231,166 - 183,259,021 (-)	NCBI		HuRef
CHM1_1	2	191,377,431 - 191,405,282 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	190,930,561 - 191,096,453 (-)	NCBI		T2T-CHM13v2.0

Nemp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	52,669,850 - 52,691,078 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	52,669,862 - 52,691,078 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	52,568,535 - 52,651,919 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	52,630,703 - 52,651,919 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	52,687,549 - 52,708,763 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	52,575,292 - 52,595,181 (+)	NCBI		MGSCv36	mm8
Celera	1	53,171,476 - 53,192,690 (+)	NCBI		Celera
Cytogenetic Map	1	C1.1	NCBI
cM Map	1	26.99	NCBI

Nemp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	8,596,778 - 8,618,508 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	8,602,056 - 8,620,417 (+)	NCBI	ChiLan1.0	ChiLan1.0

NEMP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	93,172,608 - 93,217,039 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	93,201,714 - 93,232,023 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	77,792,444 - 77,836,649 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	195,709,125 - 195,752,471 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	195,727,677 - 195,744,992 (-)	Ensembl	panpan1.1		panPan2

NEMP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	1,073,117 - 1,104,249 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	1,085,482 - 1,096,484 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	2,024,384 - 2,053,286 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	962,678 - 991,577 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	970,288 - 991,743 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	972,716 - 1,001,544 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	940,563 - 969,417 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	969,154 - 998,068 (-)	NCBI		UU_Cfam_GSD_1.0

Nemp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	149,167,855 - 149,190,491 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936506	7,656,225 - 7,670,225 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936506	7,647,575 - 7,670,215 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NEMP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	95,097,154 - 95,140,478 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	95,111,131 - 95,513,414 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	106,492,684 - 106,519,888 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NEMP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	76,007,127 - 76,036,169 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	76,009,416 - 76,026,235 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	123,436,456 - 123,464,596 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nemp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624854	5,540,486 - 5,557,971 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624854	5,534,535 - 5,562,172 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nemp2
175 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	641
Count of miRNA genes:	281
Interacting mature miRNAs:	356
Transcripts:	ENSRNOT00000029204
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	23754024	61381613	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
7207805	Bmd88	Bone mineral density QTL 88	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	9	23754024	58157242	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
6903937	Bp356	Blood pressure QTL 356		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	47902208	52283252	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat
1598823	Memor16	Memory QTL 16	1.9		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	22133322	49968732	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	27468639	72468639	Rat

Markers in Region

RH132026

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	48,861,323 - 48,861,533 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	53,713,670 - 53,713,879	NCBI	Rnor6.0
Rnor_5.0	9	53,380,987 - 53,381,196	UniSTS	Rnor5.0
RGSC_v3.4	9	45,848,717 - 45,848,926	UniSTS	RGSC3.4
Celera	9	46,530,070 - 46,530,279	UniSTS
Cytogenetic Map	9	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000029204 ⟹ ENSRNOP00000032860

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	48,861,252 - 48,880,512 (-)	Ensembl
Rnor_6.0 Ensembl	9	53,713,598 - 53,732,858 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113308 ⟹ ENSRNOP00000079039

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	48,862,406 - 48,880,512 (-)	Ensembl

RefSeq Acc Id:

NM_001134642 ⟹ NP_001128114

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	56,353,233 - 56,372,493 (-)	NCBI
mRatBN7.2	9	48,861,252 - 48,880,512 (-)	NCBI
Rnor_6.0	9	53,713,598 - 53,732,858 (-)	NCBI
Rnor_5.0	9	53,380,915 - 53,400,175 (-)	NCBI
RGSC_v3.4	9	45,848,645 - 45,867,905 (-)	RGD
Celera	9	46,529,998 - 46,549,258 (-)	RGD

Sequence:

show sequence

GTTACACTGGCCGTGATGCCCCCCGGGTCGTGGTGGCTGGTGCTTTGGCTGCCGCCCCTGGCCA
CGCTGCCAGCGGGTGCGGTGCCCCAGGAGGAGGCGGCAATGTCAGTTCCAAGATGTAAATCTCT
GAAGGAAACGGACTTAATTAAAACTTCTGTGTCAGACTGCTATTGCTACAATCAACATTCACAA
ATAGAGTGGACATATATGTGGTCAACTGTGCAGGTGACGGTTACCAGCCCGGGCCTGCTCAGTA
TTGTGTATATCACAGGAAGACATACTTGCCAGCACACAGAAACCATTCTATCTTTTCTCAAATG
TGTGACTCACAACTTTTGGACAGCAGAGGAGGCTAAGGAGGTGACCATAGTCTTCAGTCCATAC
GGAGAGACTGTGTGCTTCTCTGTAAAGCCTGTTGGGAGTTTACTTACCTATGCAGTAAGCGTGA
ATCGAAATGTTGTGGATTTCAGACTCTTCCTTGTGTTTGCGACAGGCATTTTCCTTTTCTTTTA
TGCAAAGACCTTGAGCCAAAGCCCTGTTTTCTATTACTCTTCGGGTACCGTGTTAGGTATTCTA
ATGACTCTGGTCTTTGTCCTTCTGATGACTAAGAAACACATCCCGAAGTATAGCACATTTGGGG
CGCTAATGATTGGTTGTTGGTTTGCTTCAGTTTATGTTTTGTGCCAGTTGATGGAAAATCTGAA
GTGGCTGTGGTGTGGAAACAGAATATATGTATTAGGCTATGTCTTGGTTGTCGGACTTTGTAGC
TTTTCCGCCTGTTACAGTCGCGGGCCTCCTGCTGATGAGGGGAGCAGAGACCTTCTGATGTGGG
CACTGAGGTTCCTCTCCCTCGTTCTTGTCTACACTGGTATGGCCATCTCTCAGTTTGCCTATGC
TGTTATGATCCTGCTCCTGCTCTCCTGGACTCGGCACTATCTACTGAGAGCATTCAGCTGTCTG
AGGTGGAAGGTGAGGCAGTGGTTTGCAACACGAGCACTGGTGGTGAGGTATCTCACTGATGATG
AGTACAGGGAGCAAGCGGAGGCCGAAACAGCCAGCGCTCTGGAGGAACTGCGCCAAGCCTGCTG
CCGGCCCGACTTCCCTTCCTGGCTAGCTGTCTCCAGACTCCAGGCTCCTAAAAAGTTTGCAGAG
TTTGTTCTTGGAGCGAGCCACCTGTCACCGGAAGAAGTCAGCACACACGAAAAGCAGTATGGCC
TTGGAGGTGCCTTCCTGGAAGAGCAGCTCTTTAGCCTGCAGACTGAGAGTCTACCTGCAAGCTG
ACTTCATTCTGAACCGGAAAGCAAGTAAAAGGCCAGGCTCTGATTGCAGCTGGGTGGGGCCCAA
GCACTTCAGAGAAAAGTAAACCATGCAAGTAAGGAAAAACTCATTTGCACAGGAGAGCCTTACC
GTGGTGCTGTGAAGACTGAAAGCATCGTTGCCACAGGCCCTGGATGAAGACCTTCACAGGGACA
GTGGAAACCTGTTCTTTAGGACCAGTAAACGGGACCTGATCCCTTCCCTTCGTCAGGCACTAAC
TCCCCTCTGGATGCCTGGGAGCTGGCTCAAGAGGCTGCATTATTGTCATCCCTCCCAAACCCCC
AACCTGTTTCCTCAGTACCAATGCTTTCTACGGTGAGGTTCACGTGATAGTAGGAAGTGCTGTT
GAAGGAATTCTGATGCTGGCTCTGGTTAACTCAGAGTCACATGTTCCCCAGGTTCCTCAGTCTC
CAGGCAGTGTGGGTCTCCTAAAAGGCAGATGTCATGCACAGGACTTCTAACTTACTAACCACTT
TTCATGAGACTAATAATCTTTAAAACACAGGTTTGGGAATGCTATCGATGGTAGAACTTAGGTT
TGAGTCAGGACAGAAGTGTCATGAGCAGCCTTGGCAACACTGCAGCCCTGGTGAATCTGGGACT
CACTTCTTCACATTTAGGTTCAGAGCCTTCTCCATTCAGCCTTGGTCTCATGGCCTTGGTGCCT
CAAGTTTTGTTCGTTTTGGTTTGTTTTTTGTTTTTGTTTTTTTTTTAAGCAACACCCAATTAGC
TATAACTGTGATTAAAAAGAAACATTTCTTAGGATTATATTTAATGTTTTGATAAGATTTTATA
TGCCGATGGATTAAAATTTTAATTACTTCTTGTACTTTTTATATACTGAAATTGAAGCATGGAG
GCATTTGTGACATTTTTGAGATTTATTTTTTTAAAACTTATTATATATGTTTGCAATGATTCTC
ACAAAATAGATTTGTGATATTTCTGTTTTTTTAGAGAGAGCAATGTTTCTTGATCCAGGGTAAA
CTCCAGGATGAAATGAGCTACTGACTGTGCTTTGAGCCCGAGGAAAGGAGCAGAAACACAGCCG
TAAGAGTTGACTGTAGCAGACAGACATTCTGTGATCCTCTGAGAATCAAAGTCAGGTTGTTTTA
TCTTTTGTAGTGTAATGATAAAACAACCACAAAAACAGAAAGCGTGAGAGGAAGTGGGACAAGA
CACAGTCTTGGTCTCTGTCATCCCCTGACAGTGGTGCTGACTTCGGTACTTTCTAGATTCACTC
TCAAATGATGCTGTCTCTGTGAAGCTCTGTGTCAGTGTTTCTGCCCCTGCTTTTTGACAGATAT
AGAATATCCGGAGTCTTTTTCTTTTTCTTAGAAACTTCACTCAGTTCAATCTGTGCCTTTACAT
GTTGTTGGCTTTAAAATGTCAAAGAATGGGGTCTGGAGAGATGGCTCAGTGGTTAAGAAGAGCC
TTGCAGAGGATCTGAGTTCAGTCCTCAGCATCTGAGTGGCATGGCAGCTTGCAGCCATGTATAA
CCGTAGTTCCAGGAGATCTGATACCTTCCTGTGACTTTGCTAGCACCAGTCATGTAAGTGTTGG
ACATACATACACACAAGACAAAAACACGTGTAAATAATGTGCTTCTGTTCATTTTGAGAACTAT
TCTGCCAAAATAGACAGGTGTTGTAACATTCTGTCACAGCGTAATCTGGTTTTCGTTTTTTAGT
AACTGTATTTATTGGCGGTGTATCGGTGCTGTGCACAGCCATGCTCACCTCTCACTAAGCAGTT
TGTTTAGAATGTGAGCCACCAGGACAGCCCCAGCCTTCCTGAGCTGGCAGGGACCGCACTGTGA
TTACAGCTCTCAGCAGCAAGCCAGTGTACCCACAGAAAACAGCGCAGTCTTTCGGGATGCCGTT
TTCCATGCCTATCTTTGGAAGGAATCATGGATCTGTCAGATTGTTACATGACAACTGTGAAAAG
TTAAACAATTAAAATATTTCTGGTAAAATGTT

hide sequence

RefSeq Acc Id:

XM_039084132 ⟹ XP_038940060

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	56,355,244 - 56,372,586 (-)	NCBI
mRatBN7.2	9	48,863,430 - 48,880,565 (-)	NCBI

RefSeq Acc Id:

XM_039084133 ⟹ XP_038940061

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	56,358,801 - 56,372,586 (-)	NCBI
mRatBN7.2	9	48,866,820 - 48,880,558 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001128114	(Get FASTA)	NCBI Sequence Viewer
	XP_038940060	(Get FASTA)	NCBI Sequence Viewer
	XP_038940061	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL99098	(Get FASTA)	NCBI Sequence Viewer
	EDL99099	(Get FASTA)	NCBI Sequence Viewer
	EDL99100	(Get FASTA)	NCBI Sequence Viewer
	EDL99101	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032860.3
	ENSRNOP00000079039.1
GenBank Protein	P0C8N6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001128114 ⟸ NM_001134642
- Peptide Label:	precursor
- UniProtKB:	P0C8N6 (UniProtKB/Swiss-Prot), A6INV9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPPGSWWLVLWLPPLATLPAGAVPQEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIEWTY MWSTVQVTVTSPGLLSIVYITGRHTCQHTETILSFLKCVTHNFWTAEEAKEVTIVFSPYGETVC FSVKPVGSLLTYAVSVNRNVVDFRLFLVFATGIFLFFYAKTLSQSPVFYYSSGTVLGILMTLVF VLLMTKKHIPKYSTFGALMIGCWFASVYVLCQLMENLKWLWCGNRIYVLGYVLVVGLCSFSACY SRGPPADEGSRDLLMWALRFLSLVLVYTGMAISQFAYAVMILLLLSWTRHYLLRAFSCLRWKVR QWFATRALVVRYLTDDEYREQAEAETASALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGA SHLSPEEVSTHEKQYGLGGAFLEEQLFSLQTESLPAS hide sequence

Ensembl Acc Id:

ENSRNOP00000032860 ⟸ ENSRNOT00000029204

RefSeq Acc Id:	XP_038940060 ⟸ XM_039084132
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038940061 ⟸ XM_039084133
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G4K5 (UniProtKB/TrEMBL), A6INW2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000079039 ⟸ ENSRNOT00000113308

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0C8N6-F1-model_v2	AlphaFold	P0C8N6	1-421	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696654

Promoter ID:

EPDNEW_R7179

Type:

multiple initiation site

Name:

Nemp2_1

Description:

nuclear envelope integral membrane protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	53,732,863 - 53,732,923	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560421	AgrOrtholog
BioCyc Gene	G2FUF-27613	BioCyc
Ensembl Genes	ENSRNOG00000012924	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000029204.4	UniProtKB/Swiss-Prot
	ENSRNOT00000113308.1	UniProtKB/TrEMBL
InterPro	NEMP_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:503257	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	503257	ENTREZGENE
PANTHER	NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13598	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	NEMP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Nemp2	PhenoGen
RatGTEx	ENSRNOG00000012924	RatGTEx
UniProt	A0A8I6G4K5	ENTREZGENE, UniProtKB/TrEMBL
	A6INV9	ENTREZGENE, UniProtKB/TrEMBL
	A6INW2	ENTREZGENE, UniProtKB/TrEMBL
	NEMP2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Nemp2	nuclear envelope integral membrane protein 2	LOC685327	similar to Protein KIAA0286	Data merged from RGD:1595121	737654	PROVISIONAL
2015-06-08	Nemp2	nuclear envelope integral membrane protein 2	Tmem194b	transmembrane protein 194B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-12-16	Tmem194b	transmembrane protein 194B	RGD1560421	similar to RIKEN cDNA 5330401P04	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1560421	similar to RIKEN cDNA 5330401P04	RGD1560421_predicted	similar to RIKEN cDNA 5330401P04 (predicted)	'predicted' is removed	2292626	APPROVED
2008-01-09	LOC685327	similar to Protein KIAA0286	LOC682855	similar to Protein KIAA0286	Data merged from RGD:1593993	1643240	APPROVED
2006-11-20	LOC685327	similar to Protein KIAA0286			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC682855	similar to Protein KIAA0286			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1560421_predicted	similar to RIKEN cDNA 5330401P04 (predicted)	LOC503257	similar to RIKEN cDNA 5330401P04	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC503257	similar to RIKEN cDNA 5330401P04			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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