Lipn (lipase, family member N) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Lipn (lipase, family member N) Rattus norvegicus
Analyze
Symbol: Lipn
Name: lipase, family member N
RGD ID: 1560354
Description: Predicted to enable lipase activity. Predicted to be involved in lipid metabolic process. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPN (lipase family member N); INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lipase member N; LOC499345; RGD1560354; similar to lipase-like, ab-hydrolase domain containing 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,998,154 - 241,016,658 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1240,998,154 - 241,016,658 (+)EnsemblGRCr8
mRatBN7.21231,584,950 - 231,603,456 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1231,584,956 - 231,603,468 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1239,976,758 - 239,992,921 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,898,829 - 246,914,996 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01239,736,903 - 239,753,074 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01252,375,941 - 252,394,226 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,375,933 - 252,396,460 (+)Ensemblrn6Rnor6.0
Rnor_5.01259,600,620 - 259,616,791 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41237,932,634 - 237,948,805 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1228,700,030 - 228,716,201 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Lipn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,998,154 - 241,016,658 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1240,998,154 - 241,016,658 (+)EnsemblGRCr8
mRatBN7.21231,584,950 - 231,603,456 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1231,584,956 - 231,603,468 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1239,976,758 - 239,992,921 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,898,829 - 246,914,996 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01239,736,903 - 239,753,074 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01252,375,941 - 252,394,226 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,375,933 - 252,396,460 (+)Ensemblrn6Rnor6.0
Rnor_5.01259,600,620 - 259,616,791 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41237,932,634 - 237,948,805 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1228,700,030 - 228,716,201 (+)NCBICelera
Cytogenetic Map1q52NCBI
LIPN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381088,757,226 - 88,779,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1088,759,982 - 88,779,626 (+)Ensemblhg38GRCh38
GRCh371090,519,777 - 90,539,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,511,143 - 90,527,979 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1084,268,049 - 84,284,832 (+)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1084,155,904 - 84,172,685 (+)NCBIHuRef
CHM1_11090,803,232 - 90,820,059 (+)NCBICHM1_1
T2T-CHM13v2.01089,641,224 - 89,663,572 (+)NCBIT2T-CHM13v2.0
Lipn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,044,458 - 34,063,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,044,758 - 34,062,318 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381934,067,058 - 34,085,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,067,358 - 34,084,918 (+)Ensemblmm10GRCm38
MGSCv371934,141,848 - 34,159,408 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361934,133,355 - 34,150,915 (+)NCBIMGSCv36mm8
Celera1934,844,100 - 34,861,644 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.32NCBI
Lipn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554254,187,537 - 4,205,066 (-)Ensembl
ChiLan1.0NW_0049554254,187,537 - 4,205,066 (-)NCBIChiLan1.0ChiLan1.0
LIPN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28100,779,271 - 100,798,806 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110100,784,585 - 100,804,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01085,485,727 - 85,505,268 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11088,990,571 - 89,007,327 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1088,990,571 - 89,007,327 (+)EnsemblpanPan2panpan1.1
LIPN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12638,573,408 - 38,588,171 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2638,389,877 - 38,404,593 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02640,157,832 - 40,172,516 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2640,157,878 - 40,172,515 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12637,996,879 - 38,011,552 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02637,593,517 - 37,608,223 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02638,862,983 - 38,877,692 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lipn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721378,328,481 - 78,361,805 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936735445,985 - 464,340 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936735445,985 - 464,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100156277
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14100,691,955 - 100,710,316 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.114100,678,863 - 100,710,229 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214109,671,333 - 109,695,023 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIPN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1982,182,344 - 82,201,550 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl982,185,101 - 82,201,549 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604842,863,858 - 42,881,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lipn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479115,055,126 - 15,065,876 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479115,050,707 - 15,066,223 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lipn
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1233,680,072 - 33,697,267 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lipn
49 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:29
Interacting mature miRNAs:30
Transcripts:ENSRNOT00000026242
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367243666627Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1237995023269633915Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1234540191270518180Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1238398865255849249Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1233204160270518180Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
9 2 8 41 38 40 12 31 12 6 89 59 3 22 8 37 28

Sequence


Ensembl Acc Id: ENSRNOT00000078405   ⟹   ENSRNOP00000072882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1240,998,154 - 241,016,658 (+)Ensembl
mRatBN7.2 Ensembl1231,584,956 - 231,603,468 (+)Ensembl
Rnor_6.0 Ensembl1252,375,933 - 252,396,460 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165052   ⟹   ENSRNOP00000100438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1240,998,154 - 241,015,897 (+)Ensembl
RefSeq Acc Id: NM_001191955   ⟹   NP_001178884
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,998,154 - 241,016,658 (+)NCBI
mRatBN7.21231,584,950 - 231,603,456 (+)NCBI
Rnor_6.01252,377,169 - 252,393,340 (+)NCBI
Rnor_5.01259,600,620 - 259,616,791 (+)NCBI
Celera1228,700,030 - 228,716,201 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063271729   ⟹   XP_063127799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,998,264 - 241,016,651 (+)NCBI
RefSeq Acc Id: XM_063271730   ⟹   XP_063127800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,999,022 - 241,016,651 (+)NCBI
RefSeq Acc Id: XM_063271731   ⟹   XP_063127801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81240,998,154 - 241,016,657 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178884 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127799 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127800 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127801 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13152 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072882
  ENSRNOP00000072882.2
  ENSRNOP00000100438.1
RefSeq Acc Id: NP_001178884   ⟸   NM_001191955
- Peptide Label: precursor
- UniProtKB: A0A0G2K430 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072882   ⟸   ENSRNOT00000078405
RefSeq Acc Id: XP_063127801   ⟸   XM_063271731
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K430 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127799   ⟸   XM_063271729
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K430 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127800   ⟸   XM_063271730
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K430 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100438   ⟸   ENSRNOT00000165052
Protein Domains
AB hydrolase-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K430-F1-model_v2 AlphaFold A0A0G2K430 1-380 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560354 AgrOrtholog
BioCyc Gene G2FUF-55885 BioCyc
Ensembl Genes ENSRNOG00000057173 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078405 ENTREZGENE
  ENSRNOT00000078405.3 UniProtKB/TrEMBL
  ENSRNOT00000165052.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  Lipase_euk UniProtKB/TrEMBL
KEGG Report rno:499345 UniProtKB/TrEMBL
NCBI Gene 499345 ENTREZGENE
PANTHER LYSOSOMAL ACID LIPASE-RELATED UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PhenoGen Lipn PhenoGen
PIRSF Steryl_ester_lip UniProtKB/TrEMBL
RatGTEx ENSRNOG00000057173 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A0G2K430 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L7D2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Lipn  lipase, family member N  RGD1560354_predicted  similar to lipase-like, ab-hydrolase domain containing 3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560354_predicted  similar to lipase-like, ab-hydrolase domain containing 3 (predicted)  LOC499345  similar to lipase-like, ab-hydrolase domain containing 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499345  similar to lipase-like, ab-hydrolase domain containing 3      Symbol and Name status set to provisional 70820 PROVISIONAL