Gene: Dennd4b (DENN domain containing 4B) Rattus norvegicus
Symbol: Dennd4b
Name: DENN domain containing 4B
Description: ENCODES a protein that exhibits Rab guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN regulation of Rab protein signal transduction (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; ASSOCIATED WITH autosomal dominant non-syndromic intellectual disability 18 (ortholog); Familial Prostate Cancer (ortholog); FOUND IN Golgi apparatus (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; bisphenol A; clofibrate
Type: protein-coding
RefSeq Status: MODEL
Also known as: DENN domain-containing protein 4B; DENN/MADD domain containing 4B; LOC361987; LOW QUALITY PROTEIN: DENN domain-containing protein 4B; RGD1560320; similar to brain specific protein 4
Homo sapiens (human) : DENND4B (DENN domain containing 4B)  HGNC  Alliance
Mus musculus (house mouse) : Dennd4b (DENN/MADD domain containing 4B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd4b (DENN domain containing 4B)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND4B (DENN domain containing 4B)
Canis lupus familiaris (dog) : DENND4B (DENN domain containing 4B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd4b (DENN domain containing 4B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02189,626,922 - 189,642,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02209,060,398 - 209,075,586 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,507,797 - 182,523,015 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2169,656,396 - 169,671,602 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dennd4b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560320
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE