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Gene: Dis3l2 (DIS3-like 3'-5' exoribonuclease 2) Rattus norvegicus
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Symbol: Dis3l2
Name: DIS3-like 3'-5' exoribonuclease 2
Description: Predicted to have 3'-5'-exoribonuclease activity; magnesium ion binding activity; and poly(U) RNA binding activity. Predicted to be involved in several processes, including RNA catabolic process; mitotic sister chromatid separation; and stem cell population maintenance. Predicted to localize to the P-body and exosome (RNase complex). Human ortholog(s) of this gene implicated in Perlman syndrome and nephroblastoma. Orthologous to human DIS3L2 (DIS3 like 3'-5' exoribonuclease 2); INTERACTS WITH bisphenol A; cisplatin; cobalt dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DIS3 mitotic control homolog (S. cerevisiae)-like 2; DIS3 mitotic control homolog-like 2; DIS3-like exonuclease 2; LOC367307; RGD1560168; similar to RIKEN cDNA 4930429A22
Orthologs:
Homo sapiens (human) : DIS3L2 (DIS3 like 3'-5' exoribonuclease 2)  HGNC  Alliance
Mus musculus (house mouse) : Dis3l2 (DIS3 like 3'-5' exoribonuclease 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dis3l2 (DIS3 like 3'-5' exoribonuclease 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DIS3L2 (DIS3 like 3'-5' exoribonuclease 2)
Canis lupus familiaris (dog) : DIS3L2 (DIS3 like 3'-5' exoribonuclease 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dis3l2 (DIS3 like 3'-5' exoribonuclease 2)
Sus scrofa (pig) : DIS3L2 (DIS3 like 3'-5' exoribonuclease 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0993,767,837 - 94,161,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0993,495,138 - 93,886,547 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4985,470,810 - 85,855,679 (+)NCBIRGSC3.4rn4RGSC3.4
Celera984,770,512 - 85,150,470 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dis3l2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560168
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.