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Gene: Dnah5 (dynein, axonemal, heavy chain 5) Mus musculus
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Symbol: Dnah5
Name: dynein, axonemal, heavy chain 5
Description: Exhibits microtubule motor activity. Involved in several processes, including determination of left/right symmetry; epithelial cilium movement involved in extracellular fluid movement; and lateral ventricle development. Localizes to the axonemal dynein complex. Used to study otitis media; primary ciliary dyskinesia (multiple); tetralogy of Fallot; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 3. Is expressed in trachea epithelium. Orthologous to human DNAH5 (dynein axonemal heavy chain 5); INTERACTS WITH 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU022615; axonemal beta dynein heavy chain 5; axonemal dynein heavy chain 5; b2b1134Clo; b2b1154Clo; b2b1537Clo; b2b1565Clo; b2b3491Clo; b2b601Clo; ciliary dynein heavy chain 5; Dnahc5; dynein heavy chain 5, axonemal; dynein, axon, heavy chain 5; KIAA1603; Mdnah5; mKIAA1603
Orthologs:
Homo sapiens (human) : DNAH5 (dynein axonemal heavy chain 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnah5 (dynein, axonemal, heavy chain 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnah5 (dynein axonemal heavy chain 5)
Pan paniscus (bonobo/pygmy chimpanzee) : DNAH5 (dynein axonemal heavy chain 5)
Canis lupus familiaris (dog) : DNAH5 (dynein axonemal heavy chain 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnah5 (dynein axonemal heavy chain 5)
Sus scrofa (pig) : DNAH5 (dynein axonemal heavy chain 5)
Chlorocebus sabaeus (African green monkey) : DNAH5 (dynein axonemal heavy chain 5)
Heterocephalus glaber (naked mole-rat) : Dnah5 (dynein axonemal heavy chain 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1528,203,752 - 28,472,052 (+)Ensembl
GRCm381528,154,854 - 28,472,045 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371528,133,521 - 28,401,800 (+)NCBIGRCm37mm9NCBIm37
MGSCv361528,148,355 - 28,415,259 (+)NCBImm8
Celera1528,952,222 - 29,215,703 (+)NCBICelera
Cytogenetic Map15 B1NCBI
cM Map1510.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Dnah5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558622
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.