Cdh24 (cadherin-like 24) - Rat Genome Database

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Gene: Cdh24 (cadherin-like 24) Mus musculus
Analyze
Symbol: Cdh24
Name: cadherin-like 24
RGD ID: 1558613
MGI Page MGI
Description: Predicted to enable several functions, including alpha-catenin binding activity; beta-catenin binding activity; and delta-catenin binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to act upstream of or within cell-cell adhesion. Predicted to be located in cell-cell junction. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Is expressed in several structures, including brain and retina. Orthologous to human CDH24 (cadherin 24).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700040A22Rik; cadherin 14-like; cadherin-24; ENSMUSG00000022188; EY-cadh; EY-cadherin; MGC67331
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,868,688 - 54,878,853 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,868,688 - 54,878,821 (-)EnsemblGRCm39 Ensembl
GRCm381454,631,231 - 54,642,067 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,631,231 - 54,641,364 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,250,829 - 55,260,201 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,585,436 - 53,595,523 (-)NCBIMGSCv36mm8
Celera1452,420,388 - 52,429,748 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10328938   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:22102170   PMID:24952961  
PMID:25126785   PMID:28558017   PMID:33833667  


Genomics

Comparative Map Data
Cdh24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,868,688 - 54,878,853 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,868,688 - 54,878,821 (-)EnsemblGRCm39 Ensembl
GRCm381454,631,231 - 54,642,067 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,631,231 - 54,641,364 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,250,829 - 55,260,201 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,585,436 - 53,595,523 (-)NCBIMGSCv36mm8
Celera1452,420,388 - 52,429,748 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.87NCBI
CDH24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,047,067 - 23,057,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,047,062 - 23,057,538 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,516,276 - 23,526,729 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,586,709 - 22,594,875 (-)NCBINCBI36Build 36hg18NCBI36
Build 341422,586,708 - 22,594,875NCBI
Celera143,378,962 - 3,389,437 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,633,349 - 3,643,699 (-)NCBIHuRef
CHM1_11423,514,900 - 23,525,377 (-)NCBICHM1_1
T2T-CHM13v2.01417,247,688 - 17,258,139 (-)NCBIT2T-CHM13v2.0
Cdh24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,061,588 - 32,071,323 (-)NCBIGRCr8
mRatBN7.21528,091,578 - 28,101,330 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,091,637 - 28,101,340 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01533,277,845 - 33,287,546 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,278,713 - 33,285,779 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,162,640 - 37,172,757 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,710,204 - 32,717,270 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1527,669,781 - 27,679,490 (-)NCBICelera
Cytogenetic Map15p13NCBI
Cdh24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,249,531 - 37,256,603 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,249,377 - 37,257,420 (+)NCBIChiLan1.0ChiLan1.0
CDH24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,479,600 - 24,490,032 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,696,087 - 23,706,518 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,866,958 - 3,877,393 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,963,975 - 21,974,369 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,964,897 - 21,972,528 (-)Ensemblpanpan1.1panPan2
CDH24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,359,452 - 3,369,590 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,359,875 - 3,367,942 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,308,149 - 3,318,203 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,467,319 - 3,477,376 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,467,250 - 3,475,742 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,158,726 - 3,168,781 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,219,964 - 3,230,010 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,482,028 - 3,492,086 (-)NCBIUU_Cfam_GSD_1.0
Cdh24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,113,156 - 35,123,474 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,265,219 - 1,275,920 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,265,583 - 1,276,443 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,990,220 - 76,001,130 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,990,185 - 76,001,133 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,327,040 - 81,351,723 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDH24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,416,449 - 23,427,764 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,417,354 - 23,426,738 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605922,990,284 - 23,000,750 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,485,919 - 9,494,990 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,484,779 - 9,494,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdh24
320 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:306
Count of miRNA genes:279
Interacting mature miRNAs:303
Transcripts:ENSMUST00000067784
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143322195759437449Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4733525059962593Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse

Markers in Region
RH126909  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,642,234 - 54,642,483UniSTSGRCm38
MGSCv371455,261,071 - 55,261,320UniSTSGRCm37
Celera1452,430,623 - 52,430,873UniSTS
Cytogenetic Map14C3UniSTS
Whitehead/MRC_RH14597.42UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000067784   ⟹   ENSMUSP00000066005
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,868,688 - 54,878,821 (-)Ensembl
GRCm38.p6 Ensembl1454,631,231 - 54,641,364 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227124   ⟹   ENSMUSP00000154248
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,870,010 - 54,874,998 (-)Ensembl
GRCm38.p6 Ensembl1454,632,553 - 54,637,541 (-)Ensembl
RefSeq Acc Id: NM_199470   ⟹   NP_955764
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391454,868,688 - 54,878,794 (-)NCBI
GRCm381454,631,992 - 54,641,364 (-)NCBI
MGSCv371455,250,829 - 55,260,201 (-)RGD
Celera1452,420,388 - 52,429,748 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518975   ⟹   XP_006519038
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391454,871,136 - 54,878,853 (-)NCBI
GRCm381454,633,679 - 54,642,067 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247794   ⟹   XP_030103654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391454,870,504 - 54,878,853 (-)NCBI
GRCm381454,633,106 - 54,642,067 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_955764   ⟸   NM_199470
- Peptide Label: precursor
- UniProtKB: Q6PFX6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006519038   ⟸   XM_006518975
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_030103654   ⟸   XM_030247794
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000066005   ⟸   ENSMUST00000067784
RefSeq Acc Id: ENSMUSP00000154248   ⟸   ENSMUST00000227124
Protein Domains
Cadherin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6PFX6-F1-model_v2 AlphaFold Q6PFX6 1-781 view protein structure

Promoters
RGD ID:8682358
Promoter ID:EPDNEW_M19209
Type:initiation region
Name:Cdh24_1
Description:Mus musculus cadherin-like 24 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381454,641,337 - 54,641,397EPDNEW
RGD ID:6824762
Promoter ID:MM_KWN:16888
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000067784,   NM_199470,   UC007TWO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361455,260,171 - 55,260,962 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928330 AgrOrtholog
Ensembl Genes ENSMUSG00000059674 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000067784 ENTREZGENE
  ENSMUST00000067784.8 UniProtKB/Swiss-Prot
  ENSMUST00000227124.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/Swiss-Prot
  Cadherins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/Swiss-Prot
  Cadherin_cytoplasmic-dom UniProtKB/Swiss-Prot
  Catenin_binding_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:239096 UniProtKB/Swiss-Prot
MGD MGI:1928330 ENTREZGENE
NCBI Gene 239096 ENTREZGENE
PANTHER CADHERIN-24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24027 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/Swiss-Prot
  Cadherin_C UniProtKB/Swiss-Prot
PhenoGen Cdh24 PhenoGen
PRINTS CADHERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/Swiss-Prot
  CADHERIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00112 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49313 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BQY3_MOUSE UniProtKB/TrEMBL
  CAD24_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE