Taar8b (trace amine-associated receptor 8B) - Rat Genome Database

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Gene: Taar8b (trace amine-associated receptor 8B) Mus musculus
Analyze
Symbol: Taar8b
Name: trace amine-associated receptor 8B
RGD ID: 1558427
MGI Page MGI
Description: Predicted to enable trace-amine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Is active in plasma membrane. Orthologous to human TAAR8 (trace amine associated receptor 8).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Gm1149; mTaar8b; taR-8b; trace amine associated receptor 8b; trace amine receptor 8b
RGD Orthologs
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,967,158 - 23,968,192 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,967,158 - 23,968,192 (-)EnsemblGRCm39 Ensembl
GRCm381024,091,260 - 24,092,294 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1024,091,260 - 24,092,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv371023,811,066 - 23,812,100 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,780,676 - 23,781,710 (-)NCBIMGSCv36mm8
Celera1025,024,334 - 25,025,368 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (RCA)
plasma membrane  (IBA,IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Lindemann L, etal., Genomics 2005 Mar;85(3):372-85.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11459929   PMID:12477932   PMID:16602821   PMID:16878137   PMID:17556730   PMID:21873635   PMID:25391046   PMID:38355793  


Genomics

Comparative Map Data
Taar8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,967,158 - 23,968,192 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,967,158 - 23,968,192 (-)EnsemblGRCm39 Ensembl
GRCm381024,091,260 - 24,092,294 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1024,091,260 - 24,092,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv371023,811,066 - 23,812,100 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,780,676 - 23,781,710 (-)NCBIMGSCv36mm8
Celera1025,024,334 - 25,025,368 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.43NCBI
Taar8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,122,214 - 23,126,739 (+)NCBIGRCr8
mRatBN7.2121,302,978 - 21,307,489 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,289,843 - 21,290,877 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,082,157 - 21,083,191 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,082,186 - 27,083,220 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,281,942 - 21,282,976 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0123,565,350 - 23,568,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,332,090 - 22,350,348 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0125,035,147 - 25,038,269 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,829,913 - 21,830,947 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,832,857 - 21,833,892 (+)NCBI
Celera120,055,994 - 20,057,028 (+)NCBICelera
Cytogenetic Map1p12NCBI

Variants

.
Variants in Taar8b
41 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSMUST00000092654
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532718Sluc44f_msusceptibility to lung cancer 44f (mouse)10126289265Mouse
11532717Sluc44g_msusceptibility to lung cancer 44g (mouse)10126289265Mouse
1300881Sluc29_msusceptibility to lung cancer 29 (mouse)Not determined10126289265Mouse
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1300759Geot_mgeotaxia (mouse)Not determined10126289265Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
1301659Arrd2_mage-related retinal degeneration 2 (mouse)Not determined102028318526890391Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1300997Eae15_msusceptibility to experimental allergic encephalomyelitis 15 (mouse)Not determined10440815438408276Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
11532725Sluc44b_msusceptibility to lung cancer 44b (mouse)10126289265Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
11532724Sluc44c_msusceptibility to lung cancer 44c (mouse)10126289265Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
11532723Sluc44d_msusceptibility to lung cancer 44d (mouse)10126289265Mouse
11532722Sluc44e_msusceptibility to lung cancer 44e (mouse)10126289265Mouse
11532721Sluc44_msusceptibility to lung cancer 44 (mouse)10126289265Mouse
1558857Igan1_mIgA nephropathy 1 (mouse)Not determined101771831329704155Mouse
11532720Sluc44a_msusceptibility to lung cancer 44a (mouse)10126289265Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
11533917Mts2_mmammary tumor susceptibility 2 (mouse)10126289265Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
13208570Bmiq9_mbody mass index QTL 9 (mouse)101287574424875898Mouse
1301796Mop2_mmorphine preference 2 (mouse)Not determined10928911929028424Mouse
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
Taar8a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10A4UniSTS
cM Map10 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000092654   ⟹   ENSMUSP00000090324
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1023,967,158 - 23,968,192 (-)Ensembl
GRCm38.p6 Ensembl1024,091,260 - 24,092,294 (-)Ensembl
RefSeq Acc Id: NM_001010837   ⟹   NP_001010837
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391023,967,158 - 23,968,192 (-)NCBI
GRCm381024,091,260 - 24,092,294 (-)ENTREZGENE
MGSCv371023,811,066 - 23,812,100 (-)RGD
Celera1025,024,334 - 25,025,368 (-)RGD
cM Map10 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001010837 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI39106 (Get FASTA)   NCBI Sequence Viewer  
  AAI39107 (Get FASTA)   NCBI Sequence Viewer  
  AAV70147 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000090324
  ENSMUSP00000090324.3
GenBank Protein Q5QD06 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001010837   ⟸   NM_001010837
- UniProtKB: B2RT24 (UniProtKB/Swiss-Prot),   Q5QD06 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000090324   ⟸   ENSMUST00000092654

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5QD06-F1-model_v2 AlphaFold Q5QD06 1-344 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685995 AgrOrtholog
Ensembl Genes ENSMUSG00000069702
  ENSMUSG00000100186 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000092654 ENTREZGENE
  ENSMUST00000092654.4 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  TAAR UniProtKB/Swiss-Prot
  TAAR_fam UniProtKB/Swiss-Prot
KEGG Report mmu:382348 UniProtKB/Swiss-Prot
MGD MGI:2685995 ENTREZGENE
NCBI Gene 382348 ENTREZGENE
PANTHER HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
  TRACE AMINE-ASSOCIATED RECEPTOR 8 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Taar8b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  TRACEAMINER UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt B2RT24 ENTREZGENE
  Q5QD06 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RT24 UniProtKB/Swiss-Prot