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Gene: Slc9a6 (solute carrier family 9 (sodium/hydrogen exchanger), member 6) Mus musculus
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Symbol: Slc9a6
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 6
Description: Predicted to have potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; dendritic spine development; and regulation of neurotrophin TRK receptor signaling pathway. Localizes to several cellular components, including the axon; dendrite; and endosome. Used to study Christianson syndrome. Human ortholog(s) of this gene implicated in Christianson syndrome. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human SLC9A6 (solute carrier family 9 member A6); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3732426M05; 6430520C02Rik; mKIAA0267; NHE6; sodium/hydrogen exchanger 6; solute carrier family 9 (sodium/hydrogen exchanger), isoform 6
Orthologs:
Homo sapiens (human) : SLC9A6 (solute carrier family 9 member A6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc9a6 (solute carrier family 9 member A6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a6 (solute carrier family 9 member A6)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A6 (solute carrier family 9 member A6)
Canis lupus familiaris (dog) : SLC9A6 (solute carrier family 9 member A6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a6 (solute carrier family 9 member A6)
Sus scrofa (pig) : SLC9A6 (solute carrier family 9 member A6)
Chlorocebus sabaeus (African green monkey) : SLC9A6 (solute carrier family 9 member A6)
Heterocephalus glaber (naked mole-rat) : Slc9a6 (solute carrier family 9 member A6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 EnsemblX56,609,757 - 56,664,230 (+)Ensembl
GRCm38X56,609,556 - 56,664,230 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X53,863,012 - 53,917,407 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X52,956,638 - 53,008,677 (+)NCBImm8
CeleraX43,091,843 - 43,146,238 (+)NCBICelera
Cytogenetic MapX A6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc9a6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558403
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.