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Gene: Slc9a6 (solute carrier family 9 (sodium/hydrogen exchanger), member 6) Mus musculus
Symbol: Slc9a6
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 6
Description: Predicted to have potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; dendritic spine development; and regulation of neurotrophin TRK receptor signaling pathway. Localizes to several cellular components, including the axon; dendrite; and endosome. Used to study Christianson syndrome. Human ortholog(s) of this gene implicated in Christianson syndrome. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human SLC9A6 (solute carrier family 9 member A6); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3732426M05; 6430520C02Rik; mKIAA0267; NHE6; sodium/hydrogen exchanger 6; solute carrier family 9 (sodium/hydrogen exchanger), isoform 6
Homo sapiens (human) : SLC9A6 (solute carrier family 9 member A6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc9a6 (solute carrier family 9 member A6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a6 (solute carrier family 9 member A6)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A6 (solute carrier family 9 member A6)
Canis lupus familiaris (dog) : SLC9A6 (solute carrier family 9 member A6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a6 (solute carrier family 9 member A6)
Sus scrofa (pig) : SLC9A6 (solute carrier family 9 member A6)
Chlorocebus sabaeus (African green monkey) : SLC9A6 (solute carrier family 9 member A6)
Heterocephalus glaber (naked mole-rat) : Slc9a6 (solute carrier family 9 member A6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 EnsemblX56,609,757 - 56,664,230 (+)Ensembl
GRCm38X56,609,556 - 56,664,230 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X53,863,012 - 53,917,407 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X52,956,638 - 53,008,677 (+)NCBImm8
CeleraX43,091,843 - 43,146,238 (+)NCBICelera
Cytogenetic MapX A6NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc9a6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558403
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.