Zxdc (ZXD family zinc finger C) - Rat Genome Database
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Gene: Zxdc (ZXD family zinc finger C) Mus musculus
Analyze
Symbol: Zxdc
Name: ZXD family zinc finger C
RGD ID: 1558386
MGI Page MGI
Description: Is expressed in several structures, including central nervous system; early conceptus; and gonad. Orthologous to human ZXDC (ZXD family zinc finger C); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930012H20; B930086F11Rik; BC003332; MGC7160; zinc finger protein ZXDC
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,346,460 - 90,380,472 (+)NCBIGRCm39mm39
GRCm39 Ensembl690,346,474 - 90,380,472 (+)Ensembl
GRCm38690,369,478 - 90,403,490 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,369,492 - 90,403,490 (+)EnsemblGRCm38mm10GRCm38
MGSCv37690,319,488 - 90,353,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv36690,334,982 - 90,368,990 (+)NCBImm8
Celera692,263,246 - 92,297,382 (+)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:18287559   PMID:20059953   PMID:20412781   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Zxdc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,346,460 - 90,380,472 (+)NCBIGRCm39mm39
GRCm39 Ensembl690,346,474 - 90,380,472 (+)Ensembl
GRCm38690,369,478 - 90,403,490 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,369,492 - 90,403,490 (+)EnsemblGRCm38mm10GRCm38
MGSCv37690,319,488 - 90,353,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv36690,334,982 - 90,368,990 (+)NCBImm8
Celera692,263,246 - 92,297,382 (+)NCBICelera
Cytogenetic Map6D1NCBI
ZXDC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3126,437,601 - 126,475,891 (-)EnsemblGRCh38hg38GRCh38
GRCh383126,437,348 - 126,475,938 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373126,156,444 - 126,194,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363127,639,134 - 127,677,452 (-)NCBINCBI36hg18NCBI36
Celera3124,581,266 - 124,619,586 (-)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3123,536,914 - 123,575,005 (-)NCBIHuRef
CHM1_13126,119,477 - 126,157,788 (-)NCBICHM1_1
Zxdc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24122,882,389 - 122,914,486 (+)NCBI
Rnor_6.0 Ensembl4122,282,279 - 122,312,879 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04122,282,119 - 122,314,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04186,823,155 - 186,855,265 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44124,629,459 - 124,660,467 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4111,806,376 - 111,838,676 (+)NCBICelera
Cytogenetic Map4q34NCBI
Zxdc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,687,614 - 21,724,657 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542121,686,119 - 21,724,948 (-)NCBIChiLan1.0ChiLan1.0
ZXDC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13130,802,891 - 130,840,674 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v03123,486,239 - 123,524,826 (-)NCBIMhudiblu_PPA_v0panPan3
ZXDC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl20621,331 - 651,488 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.120619,806 - 664,089 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Zxdc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936898553,680 - 581,750 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZXDC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,640,123 - 53,672,579 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,640,335 - 53,672,580 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2758,671,554 - 58,703,786 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZXDC
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12254,542,004 - 54,580,646 (+)NCBI
ChlSab1.1 Ensembl2254,542,167 - 54,579,883 (+)Ensembl
Zxdc
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624773110,812 - 149,806 (+)NCBI

Position Markers
Zxdc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
cM Map6 UniSTS
BE136473  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,382,763 - 90,382,879UniSTSGRCm38
MGSCv37690,332,757 - 90,332,873UniSTSGRCm37
Celera692,276,517 - 92,276,633UniSTS
Cytogenetic Map6D1UniSTS
Whitehead/MRC_RH6932.91UniSTS
AW048498  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,403,837 - 90,403,966UniSTSGRCm38
MGSCv37690,353,831 - 90,353,960UniSTSGRCm37
Celera692,297,733 - 92,297,862UniSTS
Cytogenetic Map6D1UniSTS
Whitehead/MRC_RH6932.71UniSTS
UniSTS:235501  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,402,616 - 90,402,745UniSTSGRCm38
MGSCv37690,352,610 - 90,352,739UniSTSGRCm37
Celera692,296,512 - 92,296,641UniSTS
Cytogenetic Map6D1UniSTS
Zxdc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2697
Count of miRNA genes:743
Interacting mature miRNAs:978
Transcripts:ENSMUST00000045740, ENSMUST00000075117, ENSMUST00000113539, ENSMUST00000137483
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_173002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_377502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC163346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000045740   ⟹   ENSMUSP00000036329
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,369,608 - 90,384,215 (+)Ensembl
RefSeq Acc Id: ENSMUST00000075117   ⟹   ENSMUSP00000074619
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,369,494 - 90,403,490 (+)Ensembl
RefSeq Acc Id: ENSMUST00000113539   ⟹   ENSMUSP00000109167
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,369,492 - 90,385,084 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137483
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,369,618 - 90,374,551 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203493   ⟹   ENSMUSP00000144992
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,369,613 - 90,383,103 (+)Ensembl
RefSeq Acc Id: NM_030260   ⟹   NP_084536
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,346,476 - 90,362,376 (+)NCBI
GRCm38690,369,494 - 90,385,394 (+)NCBI
MGSCv37690,319,488 - 90,353,480 (+)RGD
Celera692,263,246 - 92,297,382 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_173002   ⟹   NP_766590
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,346,476 - 90,380,468 (+)NCBI
GRCm38690,369,494 - 90,403,486 (+)NCBI
MGSCv37690,319,488 - 90,353,480 (+)RGD
Celera692,263,246 - 92,297,382 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_377502
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,346,460 - 90,380,472 (+)NCBI
GRCm38690,369,478 - 90,403,490 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_084536   ⟸   NM_030260
- Peptide Label: isoform 1
- UniProtKB: Q8C8V1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_766590   ⟸   NM_173002
- Peptide Label: isoform 2
- UniProtKB: Q8C8V1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000144992   ⟸   ENSMUST00000203493
RefSeq Acc Id: ENSMUSP00000036329   ⟸   ENSMUST00000045740
RefSeq Acc Id: ENSMUSP00000109167   ⟸   ENSMUST00000113539
RefSeq Acc Id: ENSMUSP00000074619   ⟸   ENSMUST00000075117

Promoters
RGD ID:6840206
Promoter ID:MM_KWN:46877
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000057963,   ENSMUST00000113539,   OTTMUST00000056952,   UC009CXD.1,   UC009CXE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36690,319,226 - 90,320,482 (+)MPROMDB
RGD ID:6890410
Promoter ID:EPDNEW_M8656
Type:initiation region
Name:Zxdc_1
Description:Mus musculus ZXD family zinc finger C , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,369,580 - 90,369,640EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1933108 AgrOrtholog
Ensembl Genes ENSMUSG00000034430 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000036329 UniProtKB/Swiss-Prot
  ENSMUSP00000074619 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000109167 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144992 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000045740 UniProtKB/Swiss-Prot
  ENSMUST00000075117 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000113539 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000203493 UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report mmu:80292 UniProtKB/Swiss-Prot
MGD MGI:1933108 ENTREZGENE
NCBI Gene 80292 ENTREZGENE
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Zxdc PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt A0A0N4SV82_MOUSE UniProtKB/TrEMBL
  Q3UVF3_MOUSE UniProtKB/TrEMBL
  Q8C8V1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3TEP2 UniProtKB/Swiss-Prot
  Q3URC2 UniProtKB/Swiss-Prot
  Q8C4U7 UniProtKB/Swiss-Prot
  Q8C4Z9 UniProtKB/Swiss-Prot
  Q8C8C2 UniProtKB/Swiss-Prot
  Q8C8T1 UniProtKB/Swiss-Prot
  Q99J65 UniProtKB/Swiss-Prot