Adamts18 (ADAM metallopeptidase with thrombospondin type 1 motif 18) - Rat Genome Database

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Gene: Adamts18 (ADAM metallopeptidase with thrombospondin type 1 motif 18) Mus musculus
Analyze
Symbol: Adamts18
Name: ADAM metallopeptidase with thrombospondin type 1 motif 18 (Ensembl:a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18)
RGD ID: 1558314
MGI Page MGI
Description: Predicted to enable metalloendopeptidase activity. Acts upstream of or within negative regulation of platelet aggregation. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including alimentary system; brain; eye; lung; and male reproductive gland or organ. Orthologous to human ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9630038L21; A disintegrin and metalloproteinase with thrombospondin motifs 18; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18; ADAMTS21; E130314N14Rik
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398114,423,755 - 114,575,975 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8114,423,758 - 114,575,370 (-)EnsemblGRCm39 Ensembl
GRCm388113,697,123 - 113,849,343 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8113,697,126 - 113,848,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv378116,222,037 - 116,372,739 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368116,584,749 - 116,734,820 (-)NCBIMGSCv36mm8
Celera8117,907,065 - 118,057,233 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map859.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7543410   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12466305   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18267097  
PMID:19218546   PMID:20637190   PMID:21267068   PMID:21677750   PMID:21862674   PMID:21873635   PMID:22386991   PMID:22407321   PMID:24194600   PMID:25770910   PMID:27626380   PMID:27638769  
PMID:28145888   PMID:28705898   PMID:28843853   PMID:29169989   PMID:29421655   PMID:30579834   PMID:31242448   PMID:31734175   PMID:32218432   PMID:32325033   PMID:32882513   PMID:34189436  
PMID:34271244   PMID:34321999   PMID:34323105   PMID:34388417   PMID:35240198   PMID:38287441  


Genomics

Comparative Map Data
Adamts18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398114,423,755 - 114,575,975 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8114,423,758 - 114,575,370 (-)EnsemblGRCm39 Ensembl
GRCm388113,697,123 - 113,849,343 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8113,697,126 - 113,848,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv378116,222,037 - 116,372,739 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368116,584,749 - 116,734,820 (-)NCBIMGSCv36mm8
Celera8117,907,065 - 118,057,233 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map859.65NCBI
ADAMTS18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381677,282,128 - 77,435,034 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1677,247,813 - 77,435,034 (-)EnsemblGRCh38hg38GRCh38
GRCh371677,316,025 - 77,468,931 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361675,873,526 - 76,026,512 (-)NCBINCBI36Build 36hg18NCBI36
Build 341675,873,928 - 76,026,512NCBI
Celera1661,613,574 - 61,766,657 (-)NCBICelera
Cytogenetic Map16q23.1NCBI
HuRef1663,072,797 - 63,225,281 (-)NCBIHuRef
CHM1_11678,727,567 - 78,880,505 (-)NCBICHM1_1
T2T-CHM13v2.01683,338,334 - 83,491,167 (-)NCBIT2T-CHM13v2.0
Adamts18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81958,596,095 - 58,749,239 (-)NCBIGRCr8
mRatBN7.21941,686,951 - 41,840,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1941,688,617 - 41,839,781 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1948,512,820 - 48,664,024 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01949,166,160 - 49,317,307 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01951,415,642 - 51,560,795 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01946,005,055 - 46,167,912 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1946,005,277 - 46,101,250 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01956,829,742 - 56,992,444 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41943,722,117 - 43,895,889 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1941,002,954 - 41,153,002 (-)NCBICelera
Cytogenetic Map19q12NCBI
Adamts18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955522532,534 - 666,523 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955522530,752 - 666,752 (-)NCBIChiLan1.0ChiLan1.0
ADAMTS18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21887,000,211 - 87,155,150 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11692,919,798 - 93,073,847 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01657,857,112 - 58,011,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11677,292,410 - 77,378,575 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1677,291,148 - 77,445,664 (-)Ensemblpanpan1.1panPan2
ADAMTS18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1573,769,462 - 73,907,024 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl573,772,114 - 73,905,264 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha573,719,683 - 73,854,779 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0574,077,460 - 74,214,474 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl574,079,598 - 74,213,369 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1574,018,089 - 74,155,401 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0573,857,334 - 73,988,950 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0574,338,384 - 74,479,803 (+)NCBIUU_Cfam_GSD_1.0
Adamts18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934933,757,816 - 33,890,335 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647525,699,840 - 25,831,284 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647525,698,117 - 25,831,291 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl610,328,944 - 10,652,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1610,488,504 - 10,652,508 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2610,445,893 - 10,488,115 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1562,764,081 - 62,921,394 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl562,765,939 - 62,918,697 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604713,131,507 - 13,289,294 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adamts18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247469,530,093 - 9,669,129 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247469,336,284 - 9,667,389 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adamts18
6232 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:968
Count of miRNA genes:495
Interacting mature miRNAs:595
Transcripts:ENSMUST00000093113
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)874126628126826739Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881819296115819296Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)882345783116345783Mouse
1301766Desp1_mdespair 1 (mouse)Not determined885486208119486373Mouse
1302049Heal1_mwound healing/regeneration 1 (mouse)Not determined886443553120443701Mouse
1301253Skmw2_mskeletal muscle weight 2 (mouse)Not determined886443553120443701Mouse
10045619Heal14_mwound healing/regeneration 14 (mouse)Not determined886443553120443701Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889726628130027694Mouse
1357494Obsty2_mobesity 2 (mouse)Not determined896245241129745061Mouse
12880431Fgf23lq2_mFGF23 serum level QTL 2 (mouse)897626632130127694Mouse
11252141Fdr2_mfat response to dietary restriction 2 (mouse)898390634130127694Mouse
1301481Lith11_mlithogenic gene 11 (mouse)Not determined898563635130127694Mouse
1302105Im1_mImmunoregulatory 1 (mouse)Not determined899828531130127694Mouse
1301080Sluc9_msusceptibility to lung cancer 9 (mouse)Not determined899828531130127694Mouse
4141435Fbtq3_mfemoral bone trait QTL 3 (mouse)Not determined8100965309130127694Mouse
1300681Pgia22_mproteoglycan induced arthritis 22 (mouse)Not determined8102486208116025457Mouse
1301316Dntcs1_mdental caries susceptibility 1 (mouse)Not determined8103443553127781786Mouse
11532691Sluc38_msusceptibility to lung cancer 38 (mouse)8105033977130127694Mouse
11532692Sluc38a_msusceptibility to lung cancer 38a (mouse)8105033977130127694Mouse
14746994Manh65_mmandible shape 65 (mouse)8106489629130127694Mouse
10412273Fcd1_mfunctional capillary density 1 (mouse)Not determined8110415083130127694Mouse
10412274Leci1_mleukocyte endothelial cell interactions 1 (mouse)Not determined8110415083130127694Mouse
11079194Tpnr6_mthermal pain response 6 (mouse)8111166632114956740Mouse
12904938Edlmmq7_mextensor digitorum longus muscle mass QTL 7 (mouse)8111481497130127694Mouse
12904960Gmmq6_mgastrocnemius muscle mass QTL 6 (mouse)8111481497130127694Mouse
4141546Mrdq3_mmodifier of retinal degeneration QTL 3 (mouse)Not determined114439420126055880Mouse

Markers in Region
Adamts18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8E1UniSTS
cM Map859.65UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001403922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001778415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001778416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_878788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC125463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ556126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB246179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO042957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000093113   ⟹   ENSMUSP00000090801
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,423,758 - 114,575,247 (-)Ensembl
GRCm38.p6 Ensembl8113,697,126 - 113,848,615 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212437   ⟹   ENSMUSP00000148288
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,425,447 - 114,571,601 (-)Ensembl
GRCm38.p6 Ensembl8113,698,815 - 113,844,969 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212527
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,501,892 - 114,571,933 (-)Ensembl
GRCm38.p6 Ensembl8113,775,260 - 113,845,301 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212665   ⟹   ENSMUSP00000148330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,424,112 - 114,571,510 (-)Ensembl
GRCm38.p6 Ensembl8113,697,480 - 113,844,878 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,491,157 - 114,575,370 (-)Ensembl
GRCm38.p6 Ensembl8113,764,525 - 113,848,738 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213076
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,441,062 - 114,501,643 (-)Ensembl
GRCm38.p6 Ensembl8113,714,430 - 113,775,011 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213078
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8114,495,138 - 114,571,936 (-)Ensembl
GRCm38.p6 Ensembl8113,768,506 - 113,845,304 (-)Ensembl
RefSeq Acc Id: NM_001403922   ⟹   NP_001390851
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,759 - 114,575,375 (-)NCBI
RefSeq Acc Id: NM_001403923   ⟹   NP_001390852
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,759 - 114,575,375 (-)NCBI
RefSeq Acc Id: NM_001403924   ⟹   NP_001390853
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,759 - 114,575,375 (-)NCBI
RefSeq Acc Id: NM_172466   ⟹   NP_766054
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,759 - 114,575,375 (-)NCBI
GRCm388113,697,123 - 113,848,839 (-)NCBI
MGSCv378116,222,037 - 116,372,739 (-)RGD
Celera8117,907,065 - 118,057,233 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530795   ⟹   XP_006530858
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,975 (-)NCBI
GRCm388113,697,123 - 113,849,343 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006530797   ⟹   XP_006530860
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,975 (-)NCBI
GRCm388113,697,123 - 113,849,343 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006530801   ⟹   XP_006530864
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,562,278 (-)NCBI
GRCm388113,697,123 - 113,835,642 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312629   ⟹   XP_017168118
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,563,057 (-)NCBI
GRCm388113,697,123 - 113,836,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312631   ⟹   XP_017168120
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,466,306 - 114,575,818 (-)NCBI
GRCm388113,739,672 - 113,849,186 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243369   ⟹   XP_030099229
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,366 (-)NCBI
GRCm388113,697,123 - 113,848,734 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243370   ⟹   XP_030099230
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,571,615 (-)NCBI
GRCm388113,697,123 - 113,844,983 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001778415
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,366 (-)NCBI
GRCm388113,697,123 - 113,848,734 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001778416
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,818 (-)NCBI
GRCm388113,738,796 - 113,849,186 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004934785
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,463,312 - 114,575,818 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004934786
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,818 (-)NCBI
Sequence:
RefSeq Acc Id: XR_878788
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398114,423,755 - 114,575,818 (-)NCBI
GRCm388113,703,359 - 113,849,186 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_766054   ⟸   NM_172466
- Peptide Label: isoform a precursor
- UniProtKB: E9QNK0 (UniProtKB/Swiss-Prot),   Q8BZD1 (UniProtKB/Swiss-Prot),   Q4VC17 (UniProtKB/Swiss-Prot),   B7ZMV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530858   ⟸   XM_006530795
- Peptide Label: isoform X1
- UniProtKB: B7ZMV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530860   ⟸   XM_006530797
- Peptide Label: isoform X3
- UniProtKB: B7ZMV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530864   ⟸   XM_006530801
- Peptide Label: isoform X4
- UniProtKB: Q8BKA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168118   ⟸   XM_017312629
- Peptide Label: isoform X2
- UniProtKB: B7ZMV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168120   ⟸   XM_017312631
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_030099229   ⟸   XM_030243369
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030099230   ⟸   XM_030243370
- Peptide Label: isoform X5
RefSeq Acc Id: ENSMUSP00000090801   ⟸   ENSMUST00000093113
RefSeq Acc Id: ENSMUSP00000148330   ⟸   ENSMUST00000212665
RefSeq Acc Id: ENSMUSP00000148288   ⟸   ENSMUST00000212437
RefSeq Acc Id: NP_001390851   ⟸   NM_001403922
- Peptide Label: isoform b precursor
- UniProtKB: B7ZMV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390852   ⟸   NM_001403923
- Peptide Label: isoform c
- UniProtKB: Q8BKA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390853   ⟸   NM_001403924
- Peptide Label: isoform c
- UniProtKB: Q8BKA1 (UniProtKB/TrEMBL)
Protein Domains
Peptidase M12B   Peptidase M12B propeptide   PLAC   Post-SET   TSP type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4VC17-F1-model_v2 AlphaFold Q4VC17 1-1219 view protein structure

Promoters
RGD ID:8668355
Promoter ID:EPDNEW_M12208
Type:initiation region
Name:Adamts18_1
Description:Mus musculus a disintegrin-like and metallopeptidase with thrombospondintype 1 motif, 18 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm388113,848,808 - 113,848,868EPDNEW
RGD ID:6842694
Promoter ID:MM_KWN:55820
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000035369
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv368116,302,531 - 116,303,031 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442600 AgrOrtholog
Ensembl Genes ENSMUSG00000053399 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000093113 ENTREZGENE
  ENSMUST00000093113.5 UniProtKB/Swiss-Prot
  ENSMUST00000212437.2 UniProtKB/TrEMBL
  ENSMUST00000212665.2 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.1620.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADAM_CR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:208936 UniProtKB/Swiss-Prot
MGD MGI:2442600 ENTREZGENE
NCBI Gene 208936 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NO LONG NERVE CORD, ISOFORM C UniProtKB/TrEMBL
Pfam ADAM_CR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAM_CR_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Reprolysin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adamts18 PhenoGen
PRINTS ADAMTSFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  TSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1D5RLA5_MOUSE UniProtKB/TrEMBL
  A0A1D5RLE1_MOUSE UniProtKB/TrEMBL
  ATS18_MOUSE UniProtKB/Swiss-Prot
  B7ZMV1 ENTREZGENE, UniProtKB/TrEMBL
  E9QNK0 ENTREZGENE
  Q3TR71_MOUSE UniProtKB/TrEMBL
  Q4VC17 ENTREZGENE
  Q8BKA1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BV18_MOUSE UniProtKB/TrEMBL
  Q8BZD1 ENTREZGENE
UniProt Secondary E9QNK0 UniProtKB/Swiss-Prot
  Q8BZD1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Adamts18  ADAM metallopeptidase with thrombospondin type 1 motif 18  Adamts18  a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18  Symbol and/or name change 5135510 APPROVED