Mef2b (myocyte enhancer factor 2B)

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Gene: Mef2b (myocyte enhancer factor 2B) Mus musculus

Analyze

Symbol:

Mef2b

Name:

myocyte enhancer factor 2B

RGD ID:

1558238

MGI Page

MGI

Description:

Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone deacetylase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to several cellular components, including cytosol; nucleoplasm; and transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; musculature; and urinary system. Orthologous to human MEF2B (myocyte enhancer factor 2B); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

AI451606; expressed sequence AI451606; myocyte-specific enhancer factor 2B

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,605,411 - 70,620,138 (+)	NCBI	GRCm39		mm39
GRCm38	8	70,152,761 - 70,167,488 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,139,711 - 70,167,488 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	72,676,677 - 72,691,387 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	73,068,698 - 73,096,477 (+)	NCBI			mm8
Celera	8	72,708,243 - 72,722,925 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.15	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

5-fluorouracil (ISO)

acetamide (ISO)

amphetamine (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP)

bis(2-chloroethyl) sulfide (EXP)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

cannabidiol (EXP)

diarsenic trioxide (ISO)

endosulfan (ISO)

folic acid (EXP)

Indeno[1,2,3-cd]pyrene (ISO)

irinotecan (ISO)

metformin (EXP)

N-methyl-4-phenylpyridinium (ISO)

pirinixic acid (ISO)

silver atom (EXP)

silver(0) (EXP)

sodium fluoride (EXP)

trimellitic anhydride (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IBA)

positive regulation of transcription by RNA polymerase II (IBA,IDA,IMP,ISO)

regulation of transcription by RNA polymerase II (IBA)

regulation of transcription, DNA-templated (IDA)

Cellular Component

cell junction (ISO)

cytosol (ISO)

nucleoplasm (ISO)

nucleus (IC,ISO)

transcription regulator complex (ISO)

Molecular Function

DNA-binding transcription activator activity, RNA polymerase II-specific (IDA,IMP,ISO)

DNA-binding transcription factor activity (IDA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

histone deacetylase binding (IDA,ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IDA,ISO)

sequence-specific double-stranded DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal mature B cell morphology (IAGP)

decreased germinal center B cell number (IAGP)

enlarged lymph nodes (IAGP)

enlarged mesenteric lymph nodes (IAGP)

enlarged spleen (IAGP)

increased B cell derived lymphoma incidence (IAGP)

increased follicular lymphoma incidence (IAGP)

increased germinal center B cell number (IAGP)

increased lymphoma incidence (IAGP)

References

References - curated


1.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	MGD data from the GO Consortium
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions
5.	Wang CC, etal., Dev Biol 2000 Aug 15;224(2):152-67.

Additional References at PubMed

PMID:7589800	PMID:7643214	PMID:7646512	PMID:8668199	PMID:8674419	PMID:8889548	PMID:8993831	PMID:9013788	PMID:9162005	PMID:9443808	PMID:10207130	PMID:10349636
PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11585834	PMID:12130539	PMID:12466851	PMID:12477932	PMID:12694204	PMID:14610273	PMID:15363409	PMID:15728583
PMID:16141072	PMID:16141073	PMID:16602821	PMID:16680724	PMID:17158926	PMID:17336904	PMID:18287559	PMID:20059953	PMID:20111592	PMID:21267068	PMID:21531906	PMID:21752992
PMID:21768366	PMID:21873635	PMID:22764880	PMID:25416778	PMID:25757744	PMID:30205047

Genomics

Comparative Map Data

Mef2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,605,411 - 70,620,138 (+)	NCBI	GRCm39		mm39
GRCm38	8	70,152,761 - 70,167,488 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,139,711 - 70,167,488 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	72,676,677 - 72,691,387 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	73,068,698 - 73,096,477 (+)	NCBI			mm8
Celera	8	72,708,243 - 72,722,925 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.15	NCBI

MEF2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	19,145,567 - 19,192,131 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	19,145,567 - 19,170,263 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	19,256,376 - 19,281,098 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	19,256,376 - 19,281,098 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	19,117,377 - 19,163,933	NCBI
Celera	19	19,161,210 - 19,185,929 (-)	NCBI
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	18,820,880 - 18,844,909 (-)	NCBI		HuRef
CHM1_1	19	19,256,090 - 19,281,608 (-)	NCBI		CHM1_1

Mef2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	16	21,001,204 - 21,017,651 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	21,001,206 - 21,017,163 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	20,851,148 - 20,867,386 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	19,736,015 - 19,752,301 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	16	19,441,650 - 19,457,610 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Mef2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	2,661,278 - 2,664,084 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	2,649,413 - 2,664,173 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100992080
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	19,585,920 - 19,610,256 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	19,585,920 - 19,610,256 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	18,583,770 - 18,609,757 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

MEF2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	20	43,991,438 - 44,017,368 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	20	44,000,253 - 44,017,371 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

LOC101954468
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936596	2,261,726 - 2,265,893 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MEF2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	58,684,555 - 58,722,741 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	58,699,173 - 58,722,554 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Position Markers

Mef2b

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	8	C1	UniSTS
cM Map	8	33.5	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
14747005	Mancz7_m	mandible centroid size 7 (mouse)					8	50053306	84053306	Mouse
27226754	Femd6_m	femur midshaft diameter 6, 10 week (mouse)					8	37400000	109600000	Mouse
10766466	Char12_m	P. chabaudi malaria resistance QTL 12 (mouse)					8	68269827	82600347	Mouse
1301952	Im3_m	immunoregulatory 3 (mouse)			Not determined		8	54706614	88706763	Mouse
14700686	Civq3_m	cerebral infarct volume QTL 3 (mouse)					8	51882191	85882191	Mouse
1357787	Vtbt5_m	vertebral trabecular bone trait 5 (mouse)			Not determined		8	65357768	99357920	Mouse
1301544	Iba3_m	induction of brown adipocytes 3 (mouse)			Not determined		8	44294880	78295025	Mouse
1301441	Skull11_m	skull morphology 11 (mouse)			Not determined		8	47737134	81737254	Mouse
10766453	Char11_m	P. chabaudi malaria resistance QTL 11 (mouse)					8	47637030	81637146	Mouse
10412287	Carg3_m	Candida albicans resistance gene 3 (mouse)			Not determined		8	55545028	89545028	Mouse
14746987	Manh64_m	mandible shape 64 (mouse)					8	50053306	84053306	Mouse
1558875	Eae31_m	experimental allergic encephalomyelitis susceptibility 31 (mouse)			Not determined		8	34642776	114837007	Mouse
12904744	Carcdq1_m	cardiac collagen deposition QTL 1 (mouse)					8	39709256	94689598	Mouse
4141797	Skmw16_m	skeletal muscle weight 16 (mouse)			Not determined		8	63939547	97939696	Mouse
4140966	Egq12_m	early growth QTL 12 (mouse)			Not determined			32016544	71287993	Mouse
1558870	Eae36_m	experimental allergic encephalomyelitis susceptibility 36 (mouse)			Not determined		8	14723160	71045600	Mouse
10043992	Hbnr11_m	Heligmosomoides bakeri nematode resistance 11 (mouse)			Not determined		8	65600207	99600347	Mouse
10043975	Obq31_m	obesity QTL 31 (mouse)			Not determined		8	58409776	92409776	Mouse
4141285	Tgq18_m	triglyceride QTL 18 (mouse)			Not determined			63460107	97460107	Mouse
11353828	Gf7_m	gonadal fat pad weight 7 (mouse)					8	58201479	92201479	Mouse
4141437	W10q14_m	weight 10 weeks QTL 14 (mouse)			Not determined			32016544	71287993	Mouse
1301506	Aevm1_m	autoimmune extremity vasculitis in MRL mice 1 (mouse)			Not determined		8	54287817	88287993	Mouse
1301013	Capsq4_m	capsaicin sensitivity related QTL 4 (mouse)			Not determined		8	36163000	92728652	Mouse
4140967	Bmd39_m	bone mineral density 39 (mouse)			Not determined		8	32016544	117238700	Mouse
1357715	Alaa3_m	alopecia areata 3 (mouse)			Not determined		8	48792939	82793021	Mouse
1301688	Orch6_m	autoimmune orchitis resistance 6 (mouse)			Not determined		8	60786850	94786976	Mouse
4141172	W6q9_m	weight 6 weeks QTL 9 (mouse)			Not determined			32016544	71287993	Mouse
1301717	Adip4_m	adiposity 4 (mouse)			Not determined		8	47637030	81637146	Mouse
1357811	Orq3_m	ovulation rate QTL 3 (mouse)			Not determined		8	32016544	71287993	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1006
Count of miRNA genes:	282
Interacting mature miRNAs:	317
Transcripts:	ENSMUST00000110140, ENSMUST00000110141, ENSMUST00000110143, ENSMUST00000110146
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001045484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC124327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB867153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC045147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO811773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D87831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D87833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D87834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D87835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D87836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000110140 ⟹ ENSMUSP00000105767

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	70,152,781 - 70,167,487 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000110141 ⟹ ENSMUSP00000105768

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	70,152,781 - 70,167,487 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000110143 ⟹ ENSMUSP00000105770

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	70,152,778 - 70,167,488 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000110146 ⟹ ENSMUSP00000105773

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	70,152,778 - 70,167,488 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000163756 ⟹ ENSMUSP00000132314

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	70,139,711 - 70,167,488 (+)	Ensembl

RefSeq Acc Id:

NM_001045484 ⟹ NP_001038949

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	70,605,411 - 70,620,138 (+)	NCBI
GRCm38	8	70,152,761 - 70,167,488 (+)	NCBI
MGSCv37	8	72,676,677 - 72,691,387 (+)	RGD
Celera	8	72,708,243 - 72,722,925 (+)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

AGTGCAGCAGAAGCATAGGCGCCTGGACCCTCACAGTGCGCAGCAGGTGTGGCCAGCAGGGACC
AGACTCCCGGGACTCCTGAGCCGCTCTGCACAGCTACCCACGATGGGGAGGAAAAAAATCCAGA
TCTCACGAATTCTAGACCAAAGGAACAGGCAGGTGACTTTCACCAAGCGCAAGTTCGGACTGAT
GAAGAAGGCTTATGAGCTGAGCGTGCTTTGTGACTGCGACATTGCCCTGATCATCTTCAACAGC
GCGCAACGCCTCTTCCAGTATGCGAGCAGCGACATGGACCGGGTGCTGCTCAAATACACCGAGT
ACAGTGAGCCGCACGAGAGCCGCACCAACGCGGATATCCTTCAGACACTGAAGAGGAGGGGCGT
GGGCCTTGATGGGCCCGAGCTGGATATGGAGGAGGGGCCAGAAGGTCCTGGAGAGAAGCTGCTG
AGGACACTGGGGGGTGACAGAGGCTCGGCCTCGCCCCCGCCTCGGATCTATCCCGTGGCCCCCG
CAATGTCGGTTTCAGAGCTGTCCTACCGGGTCCCACCAGCCACTCCAGGCTGTGATCCTGGCGG
GCTGGGGGAGGCCCCGTCTGTCCACAGCCGCCCGCCTCACTTTCGACCCCCGGGCCTGGGACAC
CCGATCTTCTCTCCAAGCCACCTTGCGAGCAAGACGCCCCCGCCTCTGTACCTGGCGACTGATG
GGCGGAGGCCAGACCTGCCCCCTGGCCTGAGAAGCCTGTACAGCGGCCTGCAGAGTCCCGGTGC
CCCAGGCCCCGCTCTGGGTAGCTTTGCCTTCTTACCATCAGGCTCCACAGATTGCAGCCCGGGA
GACGCAGCTCAGGGACCCCTGCAACCCTCACCCTGGCCACCAACGAGGGACGCTGTAGACCCCG
CCCGGCCAGTTGCCCGCAGTCTGTGCAAGGAGGGTCCCCCCAGCCGAGGGGCCTCCCCTCCGAC
ACCTCCGGTCAGCATCAAGTCTGAGCGACTGTCTCCAGTCACTGGGACCTCTGGCGACTTCCCC
AGGTCCTTCCCCTACCCGCTGCTCCTTGCCAGGCCCCTTGCAGAGCCACTGCGGCCCTCGGCCT
CCCTGCACCGCTTGACCCCTGACAGCTGGCCACGGTAGCGCTCCAAGAGGTTCCTCCAGCCTCC
ACAGAGTTCCCGAAGTCTCAGGTTCCCTATACCACCAGGACGGACGGACGAGGGCACCCACTGT
GCATCACTAAGGCCCTGTCCCTTCCTGGGGGCCGCTGCATCAATAAAGCCCAAGGACTCGGGAG
GGCACTGGGCAGCCCCTAGCTCAGAGCTCCCGAGCCTGGAATAGCCACAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001038949	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH45147	(Get FASTA)	NCBI Sequence Viewer
	BAA24539	(Get FASTA)	NCBI Sequence Viewer
	BAA24542	(Get FASTA)	NCBI Sequence Viewer
	BAA24543	(Get FASTA)	NCBI Sequence Viewer
	BAA24544	(Get FASTA)	NCBI Sequence Viewer
	BAA24545	(Get FASTA)	NCBI Sequence Viewer
	EDL28788	(Get FASTA)	NCBI Sequence Viewer
	EDL28789	(Get FASTA)	NCBI Sequence Viewer
	O55087	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001038949 ⟸ NM_001045484

- UniProtKB:

Q80VR4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDR
VLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPPP
RIYPVAPAMSVSELSYRVPPATPGCDPGGLGEAPSVHSRPPHFRPPGLGHPIFSPSHLASKTPP
PLYLATDGRRPDLPPGLRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPP
TRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLA
EPLRPSASLHRLTPDSWPR

hide sequence

RefSeq Acc Id:

ENSMUSP00000132314 ⟸ ENSMUST00000163756

RefSeq Acc Id:

ENSMUSP00000105770 ⟸ ENSMUST00000110143

RefSeq Acc Id:

ENSMUSP00000105767 ⟸ ENSMUST00000110140

RefSeq Acc Id:

ENSMUSP00000105768 ⟸ ENSMUST00000110141

RefSeq Acc Id:

ENSMUSP00000105773 ⟸ ENSMUST00000110146

Protein Domains

MADS-box

Promoters

RGD ID:

8667281

Promoter ID:

EPDNEW_M11672

Type:

single initiation site

Name:

Mef2b_1

Description:

Mus musculus myocyte enhancer factor 2B , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	70,152,761 - 70,152,821	EPDNEW

RGD ID:

6843466

Promoter ID:

MM_KWN:54664

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_4Hour, Brain, Kidney, Spleen

Transcripts:

ENSMUST00000072500, OTTMUST00000052771, OTTMUST00000071536, UC009LYX.1, UC009LYY.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	72,662,781 - 72,663,662 (+)	MPROMDB

RGD ID:

6843457

Promoter ID:

MM_KWN:54666

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

ES_Cell

Transcripts:

ENSMUST00000110140, NM_001045484, NM_008578, OTTMUST00000052776

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	72,676,471 - 72,676,971 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:104526	AgrOrtholog
Ensembl Genes	ENSMUSG00000079033	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000105767	UniProtKB/TrEMBL
	ENSMUSP00000105768	UniProtKB/TrEMBL
	ENSMUSP00000105770	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000110140	UniProtKB/TrEMBL
	ENSMUST00000110141	UniProtKB/TrEMBL
	ENSMUST00000110143	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.40.1810.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	MADS_MEF2-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_MADSbox	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_MADSbox_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:17259	UniProtKB/TrEMBL
MGD	MGI:104526	ENTREZGENE
NCBI Gene	17259	ENTREZGENE
Pfam	SRF-TF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mef2b	PhenoGen
PRINTS	MADSDOMAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	MADS_BOX_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MADS_BOX_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	MADS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF55455	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Mm.432505	ENTREZGENE
UniProt	D3Z372_MOUSE	UniProtKB/TrEMBL
	E9Q2M6_MOUSE	UniProtKB/TrEMBL
	MEF2B_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q80VR4	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	E9Q1I9	UniProtKB/TrEMBL
	G5E8P6	UniProtKB/TrEMBL
	O55088	UniProtKB/Swiss-Prot
	O55089	UniProtKB/Swiss-Prot
	O55090	UniProtKB/Swiss-Prot
	O55231	UniProtKB/Swiss-Prot
	Q61843	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-25	Mef2b	myocyte enhancer factor 2B	AI451606	expressed sequence AI451606	Data Merged	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)