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Gene: Itsn2 (intersectin 2) Mus musculus
Symbol: Itsn2
Name: intersectin 2
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity and calcium ion binding activity. Predicted to be involved in positive regulation of dendrite extension. Predicted to localize to the centrosome. Used to study nephrotic syndrome. Is expressed in several structures, including endocrine gland; ileum; male reproductive gland or organ; nervous system; and thymus. Orthologous to human ITSN2 (intersectin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI327390; EH and SH3 domains protein 2; EH domain and SH3 domain regulator of endocytosis 2; Eh domain, SH3 domain regulator of endocytosis 2; Ese2; intersectin-2; mKIAA1256; SH3 domain protein 1B; SH3 domain-containing protein 1B; Sh3d1B; Sh3p18
Homo sapiens (human) : ITSN2 (intersectin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itsn2 (intersectin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itsn2 (intersectin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ITSN2 (intersectin 2)
Canis lupus familiaris (dog) : ITSN2 (intersectin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itsn2 (intersectin 2)
Sus scrofa (pig) : ITSN2 (intersectin 2)
Chlorocebus sabaeus (green monkey) : ITSN2 (intersectin 2)
Heterocephalus glaber (naked mole-rat) : Itsn2 (intersectin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl124,592,638 - 4,713,962 (+)Ensembl
GRCm38124,592,643 - 4,713,952 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37124,599,814 - 4,720,758 (+)NCBIGRCm37mm9NCBIm37
MGSCv36124,606,965 - 4,727,848 (+)NCBImm8
Celera124,524,713 - 4,645,575 (+)NCBICelera
Cytogenetic Map12 A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Itsn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558192
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.