Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | decreases expression | EXP | | 6480464 | Nicotine results in decreased expression of SERTAD4 mRNA | CTD | PMID:21955143 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SERTAD4 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [ESR2 protein results in decreased expression of SERTAD4 mRNA] | CTD | PMID:20404318 | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:36804509 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SERTAD4 mRNA | CTD | PMID:24680724 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of SERTAD4 mRNA | CTD | PMID:25172293 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Sertad4 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SERTAD4 mRNA | CTD | PMID:30071829 | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of SERTAD4 mRNA | CTD | PMID:30951980 | 5-aza-2'-deoxycytidine | affects expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Decitabine affects the expression of SERTAD4 mRNA | CTD | PMID:23300844 | acrylamide | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of SERTAD4 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | SERTAD4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SERTAD4 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SERTAD4 mRNA | CTD | PMID:21934132 more ... | arsane | affects methylation | ISO | SERTAD4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of SERTAD4 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | SERTAD4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of SERTAD4 gene | CTD | PMID:25304211 | atrazine | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SERTAD4 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases methylation | ISO | SERTAD4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SERTAD4 5' UTR | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SERTAD4 mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | ISO | Sertad4 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SERTAD4 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SERTAD4 gene | CTD | PMID:31601247 | bisphenol A | affects methylation | ISO | SERTAD4 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of SERTAD4 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | Sertad4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SERTAD4 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SERTAD4 mRNA | CTD | PMID:29275510 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SERTAD4 mRNA | CTD | PMID:30951980 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of SERTAD4 mRNA | CTD | PMID:30951980 | cadmium atom | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of SERTAD4 mRNA | CTD | PMID:24376830 | cannabidiol | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of SERTAD4 mRNA | CTD | PMID:33244087 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of SERTAD4 mRNA | CTD | PMID:32715474 | cisplatin | decreases expression | ISO | Sertad4 (Rattus norvegicus) | 6480464 | Cisplatin results in decreased expression of SERTAD4 mRNA | CTD | PMID:22023808 | cisplatin | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of SERTAD4 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of SERTAD4 mRNA | CTD | PMID:27392435 | cisplatin | affects expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Cisplatin affects the expression of SERTAD4 mRNA | CTD | PMID:23300844 | cobalt atom | increases expression | EXP | | 6480464 | Cobalt results in increased expression of SERTAD4 mRNA | CTD | PMID:34468815 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SERTAD4 mRNA | CTD | PMID:30529165 | diuron | decreases expression | ISO | Sertad4 (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of SERTAD4 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SERTAD4 mRNA | CTD | PMID:27188386 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of SERTAD4 mRNA | CTD | PMID:21955143 | ethylparaben | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of SERTAD4 mRNA | CTD | PMID:37690743 | fulvestrant | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SERTAD4 gene | CTD | PMID:31601247 | hydrogen peroxide | affects expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of SERTAD4 mRNA | CTD | PMID:20044591 | morphine | increases expression | EXP | | 6480464 | Morphine results in increased expression of SERTAD4 mRNA | CTD | PMID:21955143 | nickel atom | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Nickel results in decreased expression of SERTAD4 mRNA | CTD | PMID:24768652 and PMID:25583101 | niclosamide | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of SERTAD4 mRNA | CTD | PMID:36318118 | nicotine | decreases expression | EXP | | 6480464 | Nicotine results in decreased expression of SERTAD4 mRNA | CTD | PMID:21955143 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SERTAD4 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SERTAD4 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SERTAD4 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SERTAD4 mRNA | CTD | PMID:26690555 | perfluorohexanesulfonic acid | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in increased expression of SERTAD4 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of SERTAD4 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of SERTAD4 mRNA | CTD | PMID:25812627 | progesterone | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of SERTAD4 mRNA | CTD | PMID:21795739 | SB 431542 | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Silver results in increased expression of SERTAD4 mRNA | CTD | PMID:28959546 | silver(0) | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Silver results in increased expression of SERTAD4 mRNA | CTD | PMID:28959546 | sodium dodecyl sulfate | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in increased expression of SERTAD4 mRNA | CTD | PMID:31734321 | tamoxifen | increases expression | EXP | | 6480464 | Tamoxifen results in increased expression of SERTAD4 mRNA | CTD | PMID:25123088 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of SERTAD4 mRNA | CTD | PMID:17484886 | trichostatin A | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of SERTAD4 mRNA | CTD | PMID:24935251 | triclosan | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Triclosan results in increased expression of SERTAD4 mRNA | CTD | PMID:30510588 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of SERTAD4 mRNA | CTD | PMID:17963808 | valproic acid | multiple interactions | ISO | SERTAD4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERTAD4 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SERTAD4 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SERTAD4 mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | ISO | SERTAD4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SERTAD4 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SERTAD4 mRNA | CTD | PMID:23179753 and PMID:28001369 | vorinostat | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | vorinostat results in increased expression of SERTAD4 mRNA | CTD | PMID:26272509 | zinc sulfate | increases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | Zinc Sulfate results in increased expression of SERTAD4 mRNA | CTD | PMID:16330358 | zoledronic acid | decreases expression | ISO | SERTAD4 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of SERTAD4 mRNA | CTD | PMID:24714768 | |