Appl2 (adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Appl2 (adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2) Mus musculus
Analyze
Symbol: Appl2
Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
RGD ID: 1558154
MGI Page MGI
Description: Predicted to have phospholipid binding activity; protein homodimerization activity; and small GTPase binding activity. Involved in several processes, including adiponectin-activated signaling pathway; cellular response to hepatocyte growth factor stimulus; and regulation of vesicle-mediated transport. Localizes to early phagosome membrane; macropinosome; and ruffle membrane. Is expressed in several structures, including alimentary system; autopod; brain; neural retina; and ventricular layer. Orthologous to human APPL2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adapter protein containing PH domain, PTB domain and leucine zipper motif 2; DCC-interacting protein 13-beta; Dip; DIP13 beta; dip13-beta; Dip3 beta; Dip3b
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391083,435,897 - 83,484,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl1083,435,897 - 83,484,602 (-)Ensembl
GRCm381083,600,033 - 83,648,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1083,600,033 - 83,648,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv371083,062,778 - 83,111,409 (-)NCBIGRCm37mm9NCBIm37
MGSCv361083,029,832 - 83,078,463 (-)NCBImm8
Celera1085,587,519 - 85,636,067 (-)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
1. MGD data from the GO Consortium
2. RGD automated import pipeline
3. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15226823   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16622416   PMID:18799693   PMID:19661063   PMID:20040596   PMID:20665729   PMID:21267068   PMID:21677750   PMID:21873635   PMID:24879834   PMID:25328665   PMID:25568335  
PMID:26445298   PMID:26764384   PMID:27219021   PMID:28965332   PMID:29467283   PMID:29675572   PMID:32325033   PMID:32553114   PMID:32581705   PMID:33122440  


Genomics

Comparative Map Data
Appl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391083,435,897 - 83,484,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl1083,435,897 - 83,484,602 (-)Ensembl
GRCm381083,600,033 - 83,648,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1083,600,033 - 83,648,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv371083,062,778 - 83,111,409 (-)NCBIGRCm37mm9NCBIm37
MGSCv361083,029,832 - 83,078,463 (-)NCBImm8
Celera1085,587,519 - 85,636,067 (-)NCBICelera
Cytogenetic Map10C1NCBI
APPL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12105,173,297 - 105,236,203 (-)EnsemblGRCh38hg38GRCh38
GRCh3812105,173,297 - 105,236,174 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712105,567,078 - 105,629,952 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612104,091,205 - 104,154,138 (-)NCBINCBI36hg18NCBI36
Celera12105,231,366 - 105,294,273 (-)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12102,626,453 - 102,689,404 (-)NCBIHuRef
CHM1_112105,532,775 - 105,595,738 (-)NCBICHM1_1
Appl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2720,135,248 - 20,184,757 (+)NCBI
Rnor_6.0 Ensembl726,256,459 - 26,306,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0726,256,179 - 26,306,128 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0726,387,115 - 26,436,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4722,279,273 - 22,328,427 (+)NCBIRGSC3.4rn4RGSC3.4
Celera717,339,053 - 17,386,872 (+)NCBICelera
Cytogenetic Map7q13NCBI
Appl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540539,503,020 - 39,540,335 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540539,503,020 - 39,540,069 (-)NCBIChiLan1.0ChiLan1.0
APPL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112106,150,955 - 106,214,038 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12106,151,969 - 106,206,879 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012102,755,388 - 102,818,686 (-)NCBIMhudiblu_PPA_v0panPan3
APPL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,192,261 - 33,243,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1033,191,602 - 33,242,669 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1033,111,933 - 33,162,406 (+)NCBI
ROS_Cfam_1.01034,033,756 - 34,084,221 (+)NCBI
UMICH_Zoey_3.11033,769,093 - 33,819,698 (+)NCBI
UNSW_CanFamBas_1.01034,053,225 - 34,103,854 (+)NCBI
UU_Cfam_GSD_1.01034,246,325 - 34,297,170 (+)NCBI
Appl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494516,467,066 - 16,530,048 (+)NCBI
SpeTri2.0NW_0049364929,477,483 - 9,526,692 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APPL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl579,356,047 - 79,412,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1579,356,046 - 79,412,235 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2582,650,763 - 82,706,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q2.3NCBI
APPL2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111100,400,093 - 100,469,234 (-)NCBI
ChlSab1.1 Ensembl11100,400,084 - 100,462,507 (-)Ensembl
Appl2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247503,789,015 - 3,827,079 (+)NCBI

Position Markers
D19286  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381083,600,262 - 83,600,452UniSTSGRCm38
MGSCv371083,063,007 - 83,063,197UniSTSGRCm37
Celera1085,587,748 - 85,587,938UniSTS
Cytogenetic Map10C1UniSTS
Whitehead_YAC10 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082473556116473795Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082473556116473795Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106565510499655287Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined105001240884012633Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101282830784243920Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1282830784243920Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
14746991Manh68_mmandible shape 68 (mouse)105244466786444667Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082473556116473795Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101282830784243920Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101282830784243920Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined105001244384012618Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
4141382Ssrq4_mstress response QTL 4 (mouse)Not determined8265510491020240Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105125566085255809Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082473556116473795Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
1357893Lvrq4_mliver weight QTL 4 (mouse)Not determined101282830784243920Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105125566085255809Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106701240892422811Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082242550116242550Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082556941116557090Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105868113592681262Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined105001244384012618Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1282830784243920Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1282830784243920Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106565510499655287Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078545406112545406Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101282830784243920Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082473556116473795Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83181141117181274Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
12910789Pwgrq19_mpost-weaning growth rate QTL 19 (mouse)108299286692333194Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined105001240884012633Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082473556116473795Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1282830784243920Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined105001240884012633Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106565510499655287Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1932
Count of miRNA genes:793
Interacting mature miRNAs:1052
Transcripts:ENSMUST00000020500, ENSMUST00000127788, ENSMUST00000130285, ENSMUST00000133719, ENSMUST00000141048, ENSMUST00000146876, ENSMUST00000147118, ENSMUST00000147582, ENSMUST00000148096, ENSMUST00000150351, ENSMUST00000150685, ENSMUST00000176294, ENSMUST00000176675, ENSMUST00000177187
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_380384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC153508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY113706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000020500   ⟹   ENSMUSP00000020500
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,600,033 - 83,648,738 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127788
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,608,607 - 83,611,102 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130285
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,602,767 - 83,611,881 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133719
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,620,827 - 83,637,443 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141048
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,601,904 - 83,603,384 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146876   ⟹   ENSMUSP00000121336
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,617,419 - 83,648,665 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147118
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,614,259 - 83,628,302 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147582
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,605,645 - 83,648,670 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148096
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,602,871 - 83,611,268 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150351
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,605,765 - 83,611,728 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150685   ⟹   ENSMUSP00000115903
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,620,713 - 83,648,603 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176294   ⟹   ENSMUSP00000135645
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,624,646 - 83,648,675 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176675   ⟹   ENSMUSP00000135672
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,600,742 - 83,609,008 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177187   ⟹   ENSMUSP00000135157
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1083,600,397 - 83,603,130 (-)Ensembl
RefSeq Acc Id: NM_145220   ⟹   NP_660255
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,484,528 (-)NCBI
GRCm381083,600,033 - 83,648,664 (-)NCBI
MGSCv371083,062,778 - 83,111,409 (-)RGD
Celera1085,587,519 - 85,636,067 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513508   ⟹   XP_006513571
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,476,958 (-)NCBI
GRCm381083,600,039 - 83,630,943 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006513509   ⟹   XP_006513572
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,903 - 83,484,741 (-)NCBI
GRCm381083,600,039 - 83,648,877 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006513510   ⟹   XP_006513573
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,474,790 (-)NCBI
GRCm381083,600,039 - 83,638,924 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006513511   ⟹   XP_006513574
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,484,645 (-)NCBI
GRCm381083,600,039 - 83,648,843 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313895   ⟹   XP_017169384
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,903 - 83,474,790 (-)NCBI
GRCm381083,600,039 - 83,638,924 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245026   ⟹   XP_030100886
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,474,790 (-)NCBI
GRCm381083,600,039 - 83,638,924 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245027   ⟹   XP_030100887
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,474,790 (-)NCBI
GRCm381083,600,039 - 83,638,924 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155744   ⟹   XP_036011637
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,474,790 (-)NCBI
RefSeq Acc Id: XM_036155745   ⟹   XP_036011638
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,474,790 (-)NCBI
RefSeq Acc Id: XM_036155746   ⟹   XP_036011639
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,476,955 (-)NCBI
RefSeq Acc Id: XM_036155747   ⟹   XP_036011640
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,474,790 (-)NCBI
RefSeq Acc Id: XM_036155748   ⟹   XP_036011641
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,484,476 (-)NCBI
RefSeq Acc Id: XM_036155749   ⟹   XP_036011642
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,472,017 (-)NCBI
RefSeq Acc Id: XR_380384
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,435,897 - 83,484,741 (-)NCBI
GRCm381083,602,850 - 83,648,877 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_660255   ⟸   NM_145220
- UniProtKB: Q8K3G9 (UniProtKB/Swiss-Prot),   Q3TVI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513574   ⟸   XM_006513511
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006513572   ⟸   XM_006513509
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006513573   ⟸   XM_006513510
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006513571   ⟸   XM_006513508
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169384   ⟸   XM_017313895
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030100887   ⟸   XM_030245027
- Peptide Label: isoform X3
RefSeq Acc Id: XP_030100886   ⟸   XM_030245026
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000115903   ⟸   ENSMUST00000150685
RefSeq Acc Id: ENSMUSP00000135157   ⟸   ENSMUST00000177187
RefSeq Acc Id: ENSMUSP00000020500   ⟸   ENSMUST00000020500
RefSeq Acc Id: ENSMUSP00000121336   ⟸   ENSMUST00000146876
RefSeq Acc Id: ENSMUSP00000135672   ⟸   ENSMUST00000176675
RefSeq Acc Id: ENSMUSP00000135645   ⟸   ENSMUST00000176294
RefSeq Acc Id: XP_036011641   ⟸   XM_036155748
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036011639   ⟸   XM_036155746
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036011640   ⟸   XM_036155747
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036011638   ⟸   XM_036155745
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036011637   ⟸   XM_036155744
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036011642   ⟸   XM_036155749
- Peptide Label: isoform X5
Protein Domains
BAR   PH   PID

Promoters
RGD ID:6819004
Promoter ID:MM_KWN:5127
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   MEF_B6
Transcripts:OTTMUST00000069204
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361083,065,691 - 83,066,992 (-)MPROMDB
RGD ID:6819003
Promoter ID:MM_KWN:5128
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B6
Transcripts:OTTMUST00000069203,   OTTMUST00000069205,   OTTMUST00000069206,   OTTMUST00000069207,   OTTMUST00000069208
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361083,073,941 - 83,075,572 (-)MPROMDB
RGD ID:6819005
Promoter ID:MM_KWN:5129
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:OTTMUST00000069209
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361083,091,631 - 83,092,131 (-)MPROMDB
RGD ID:6819001
Promoter ID:MM_KWN:5130
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000069201
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361083,099,981 - 83,100,481 (-)MPROMDB
RGD ID:6819002
Promoter ID:MM_KWN:5131
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000068884,   OTTMUST00000069007,   OTTMUST00000069200,   OTTMUST00000069202
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361083,111,201 - 83,111,747 (-)MPROMDB
RGD ID:8672884
Promoter ID:EPDNEW_M14473
Type:initiation region
Name:Appl2_1
Description:Mus musculus adaptor protein, phosphotyrosine interaction, PHdomain and leucine zipper containing 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381083,648,646 - 83,648,706EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2384914 AgrOrtholog
Ensembl Genes ENSMUSG00000020263 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000020500 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000115903 UniProtKB/TrEMBL
  ENSMUSP00000121336 UniProtKB/TrEMBL
  ENSMUSP00000135157 UniProtKB/TrEMBL
  ENSMUSP00000135645 UniProtKB/TrEMBL
  ENSMUSP00000135672 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020500 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000146876 UniProtKB/TrEMBL
  ENSMUST00000150685 UniProtKB/TrEMBL
  ENSMUST00000176294 UniProtKB/TrEMBL
  ENSMUST00000176675 UniProtKB/TrEMBL
  ENSMUST00000177187 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:216190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2384914 ENTREZGENE
NCBI Gene 216190 ENTREZGENE
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Appl2 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z340_MOUSE UniProtKB/TrEMBL
  D6RFR7_MOUSE UniProtKB/TrEMBL
  DP13B_MOUSE UniProtKB/Swiss-Prot
  H3BJX0_MOUSE UniProtKB/TrEMBL
  H3BL43_MOUSE UniProtKB/TrEMBL
  H3BL67_MOUSE UniProtKB/TrEMBL
  Q3TB15_MOUSE UniProtKB/TrEMBL
  Q3TGG0_MOUSE UniProtKB/TrEMBL
  Q3TVI6 ENTREZGENE, UniProtKB/TrEMBL
  Q3U3Y3_MOUSE UniProtKB/TrEMBL
  Q8K3G9 ENTREZGENE
UniProt Secondary Q99LT7 UniProtKB/Swiss-Prot