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Gene: Grhl2 (grainyhead like transcription factor 2) Mus musculus
Symbol: Grhl2
Name: grainyhead like transcription factor 2
Description: Exhibits DNA binding activity; DNA-binding transcription factor activity; and chromatin binding activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and growth. Localizes to the nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and sensory organ. Orthologous to human GRHL2 (grainyhead like transcription factor 2); INTERACTS WITH 1,1-dichloroethene; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610015A08Rik; BOM; brother of mammalian grainyhead; clft3; grainyhead like 2; grainyhead-like 2; grainyhead-like 2 (Drosophila); grainyhead-like protein 2 homolog; grainyheadlike; Tcfcp2l3; transcription factor CP2-like 3
Homo sapiens (human) : GRHL2 (grainyhead like transcription factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grhl2 (grainyhead-like transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grhl2 (grainyhead like transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GRHL2 (grainyhead like transcription factor 2)
Canis lupus familiaris (dog) : GRHL2 (grainyhead like transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grhl2 (grainyhead like transcription factor 2)
Sus scrofa (pig) : GRHL2 (grainyhead like transcription factor 2)
Chlorocebus sabaeus (green monkey) : GRHL2 (grainyhead like transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Grhl2 (grainyhead like transcription factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1537,233,036 - 37,363,569 (+)Ensembl
GRCm381537,232,821 - 37,363,569 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371537,162,791 - 37,293,324 (+)NCBIGRCm37mm9NCBIm37
MGSCv361537,177,836 - 37,308,152 (+)NCBImm8
Celera1537,856,086 - 37,983,260 (+)NCBICelera
Cytogenetic Map15 B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Grhl2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558066
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.