Grhl2 (grainyhead like transcription factor 2) - Rat Genome Database

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Gene: Grhl2 (grainyhead like transcription factor 2) Mus musculus
Analyze
Symbol: Grhl2
Name: grainyhead like transcription factor 2
RGD ID: 1558066
MGI Page MGI
Description: Enables DNA-binding transcription factor activity; chromatin binding activity; and intronic transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermis development; epithelial cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and face development. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610015A08Rik; BO; BOM; brother of mammalian grainyhead; clft; clft3; grainyhead like 2; grainyhead-like 2; grainyhead-like 2 (Drosophila); grainyhead-like protein 2 homolog; grainyheadlike; Tcfcp2; Tcfcp2l3; transcription factor CP2-like 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391537,233,065 - 37,363,813 (+)NCBIGRCm39mm39
GRCm39 Ensembl1537,233,280 - 37,363,813 (+)Ensembl
GRCm381537,232,821 - 37,363,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1537,233,036 - 37,363,569 (+)EnsemblGRCm38mm10GRCm38
MGSCv371537,162,791 - 37,293,324 (+)NCBIGRCm37mm9NCBIm37
MGSCv361537,177,836 - 37,308,152 (+)NCBImm8
Celera1537,856,086 - 37,983,260 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell-cell junction  (ISO)
membrane  (IEA)
nucleoplasm  (ISO)
nucleus  (IBA,IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal wall morphology  (IEA)
abnormal blood vessel morphology  (IEA)
abnormal body wall morphology  (IAGP)
abnormal caudal neuropore morphology  (IAGP)
abnormal craniofacial morphology  (IEA)
abnormal cranium morphology  (IAGP)
abnormal forebrain development  (IEA)
abnormal head shape  (IEA)
abnormal heart morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal hindbrain development  (IEA)
abnormal limb morphology  (IEA)
abnormal midbrain development  (IEA)
abnormal midface morphology  (IAGP)
abnormal neural fold elevation formation  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal optic vesicle formation  (IEA)
abnormal pericardium morphology  (IEA)
abnormal placenta morphology  (IEA)
abnormal respiratory conducting tube morphology  (IAGP)
coloboma  (IAGP)
cranioschisis  (IAGP)
curly tail  (IAGP)
decreased brain size  (IAGP)
decreased embryo size  (IAGP)
decreased litter size  (IAGP)
delayed neural tube closure  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
encephalomeningocele  (IAGP)
everted embryonic neuroepithelium  (IAGP)
exencephaly  (IAGP)
facial cleft  (IAGP)
incomplete caudal neuropore closure  (IAGP)
incomplete rostral neuropore closure  (IAGP)
increased exploration in new environment  (IEA)
interdigital webbing  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality, incomplete penetrance  (IAGP)
midline facial cleft  (IAGP)
open neural tube  (IAGP)
preweaning lethality, complete penetrance  (IEA)
small lung lobe  (IAGP)
spina bifida  (IAGP)
split sternum  (IAGP)
split vertebrae  (IAGP)
syndactyly  (IAGP)
thin ventricular wall  (IAGP)
thoracoabdominoschisis  (IAGP)
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12175488   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14681479   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:16831572   PMID:18287559   PMID:18799693   PMID:20059953   PMID:20362541   PMID:20412781   PMID:20654612   PMID:20978075   PMID:21081122   PMID:21262862   PMID:21267068   PMID:21377456  
PMID:21515572   PMID:21693562   PMID:21873635   PMID:21905163   PMID:22696678   PMID:22711520   PMID:22955271   PMID:22988430   PMID:23284647   PMID:23562608   PMID:23690579   PMID:23814079  
PMID:23892456   PMID:24375798   PMID:24952961   PMID:25758223   PMID:25788534   PMID:26177923   PMID:26206133   PMID:26288816   PMID:26527742   PMID:26584622   PMID:26903501   PMID:26989192  
PMID:27564454   PMID:27907249   PMID:29237740   PMID:29735981   PMID:30017589   PMID:30189017   PMID:30194919   PMID:30728831   PMID:31171776   PMID:31340691   PMID:31644911   PMID:31782997  
PMID:32005677   PMID:32324317  


Genomics

Comparative Map Data
Grhl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391537,233,065 - 37,363,813 (+)NCBIGRCm39mm39
GRCm39 Ensembl1537,233,280 - 37,363,813 (+)Ensembl
GRCm381537,232,821 - 37,363,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1537,233,036 - 37,363,569 (+)EnsemblGRCm38mm10GRCm38
MGSCv371537,162,791 - 37,293,324 (+)NCBIGRCm37mm9NCBIm37
MGSCv361537,177,836 - 37,308,152 (+)NCBImm8
Celera1537,856,086 - 37,983,260 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
GRHL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8101,492,439 - 101,669,726 (+)EnsemblGRCh38hg38GRCh38
GRCh388101,492,439 - 101,678,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378102,504,667 - 102,681,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,574,162 - 102,750,995 (+)NCBINCBI36hg18NCBI36
Build 348102,574,161 - 102,750,995NCBI
Celera898,689,599 - 98,866,864 (+)NCBI
Cytogenetic Map8q22.3NCBI
HuRef897,702,727 - 97,879,982 (+)NCBIHuRef
CHM1_18102,544,909 - 102,722,208 (+)NCBICHM1_1
Grhl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2768,400,287 - 68,530,269 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl776,059,386 - 76,197,856 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0776,058,623 - 76,197,360 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0776,188,138 - 76,317,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4772,742,859 - 72,872,351 (+)NCBIRGSC3.4rn4RGSC3.4
Celera765,469,270 - 65,597,175 (+)NCBICelera
Cytogenetic Map7q22NCBI
Grhl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541726,401,363 - 26,533,297 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541726,401,337 - 26,533,297 (+)NCBIChiLan1.0ChiLan1.0
GRHL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18100,295,531 - 100,471,830 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8100,308,575 - 100,471,830 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0898,129,147 - 98,308,120 (+)NCBIMhudiblu_PPA_v0panPan3
GRHL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1133,204,898 - 3,362,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl133,204,925 - 3,362,096 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha133,204,498 - 3,362,392 (+)NCBI
ROS_Cfam_1.0133,362,118 - 3,520,180 (+)NCBI
UMICH_Zoey_3.1133,205,577 - 3,363,466 (+)NCBI
UNSW_CanFamBas_1.0133,318,462 - 3,476,089 (+)NCBI
UU_Cfam_GSD_1.0133,335,250 - 3,493,208 (+)NCBI
Grhl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530334,430,577 - 34,577,590 (-)NCBI
SpeTri2.0NW_00493647041,856,683 - 41,961,666 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRHL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl435,371,136 - 35,564,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1435,368,788 - 35,565,394 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2438,263,513 - 38,412,524 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRHL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1896,340,459 - 96,526,366 (+)NCBI
ChlSab1.1 Ensembl896,342,189 - 96,526,363 (+)Ensembl
Vero_WHO_p1.0NW_02366603944,151,564 - 44,338,050 (-)NCBI
Grhl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476318,784,815 - 18,916,358 (+)NCBI

Position Markers
41.MMHAP64FRF11.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381537,311,204 - 37,311,356UniSTSGRCm38
MGSCv371537,240,959 - 37,241,111UniSTSGRCm37
Celera1537,930,816 - 37,930,968UniSTS
Cytogenetic Map15CUniSTS
Whitehead_YAC15 UniSTS
D15Mit49  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381537,260,048 - 37,260,225UniSTSGRCm38
MGSCv371537,189,803 - 37,189,980UniSTSGRCm37
Celera1537,878,242 - 37,878,419UniSTS
Cytogenetic Map15CUniSTS
cM Map1515.2UniSTS
Whitehead Genetic1516.4UniSTS
Whitehead_YAC15 UniSTS
Grhl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15CUniSTS
cM Map1514.84UniSTS
AU049954  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371537,170,891 - 37,171,150UniSTSGRCm37
Celera1537,864,185 - 37,864,444UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15344490771325689Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined346021278717086Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined346021278717086Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined346021278717086Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15346021278717086Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15346021278717086Mouse
4141358Ath22_matherosclerosis 22 (mouse)Not determined346456637464566Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562040839620528Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15610000038000000Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15610000050900000Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15610000068400000Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15610000071600000Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15610000072600000Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15610000076000000Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15610000076500000Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15610000078800000Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15610000086800000Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156100000100900000Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15680000045100000Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15690000076000000Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15690000076000000Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15690000084700000Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15720000055400000Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15760000055400000Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15760000059400000Mouse
27095922Pglq11_mpelvic girdle length QTL 11, 10 week (mouse)15810000038900000Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15810000047800000Mouse
4140994Shali3_msurvival time to hyperoxic acute lung injury 3 (mouse)Not determined927293643448484Mouse
10412172Habiir5_mhyperoxic acute lung injury imprinted region 5 (mouse)Not determined15927293643448484Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927293656323454Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927293679590561Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402117102988123Mouse
1302165Yv_myellow value (mouse)Not determined151384686047847002Mouse
1301020Pheo_mpheomelanin (mouse)Not determined151384686047847002Mouse
1301951Eila3_methanol induced locomotor activity 3 (mouse)Not determined151492744148927610Mouse
4141423Nstr2_mnerve sheath tumor resistance QTL 2 (mouse)Not determined1492744148927610Mouse
1302007Bbaa14_mB.burgdorferi-associated arthritis 14 (mouse)Not determined151492744148927610Mouse
1301499Bdln2_mbody length 2 (mouse)Not determined151564519749645324Mouse
12859288Criq1_mCitrobacter rodentium infection QTL 1 (mouse)151603380850033808Mouse
26884423Zlq10_mzygomatic length QTL 10, 16 week (mouse)152060000050900000Mouse
14928313Manh78_mmandible shape 78 (mouse)152148439755484397Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152273036956730369Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2302961857029764Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152459917658599409Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152543241059432532Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2562158259621582Mouse
1301063Dob4_mdietary obesity 4 (mouse)4.3Body weightmesenteric152603559437781057Mouse
1301760Dob9_mdietary obesity 9 (mouse)Body fat amountadiposity index152603559437781057Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152644838460448484Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152644838460448484Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162644838460448484Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152644838460448484Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660000066500000Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152841925062419343Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152841925062419343Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800000102100000Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930000076200000Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020000058100000Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578270103517472Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153414129868141408Mouse
12904003Opfaq12_mopen field activity QTL 12 (mouse)153435876538447657Mouse
1301324Cdif_mcolor difference (mouse)Not determined153611251070112623Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1650
Count of miRNA genes:711
Interacting mature miRNAs:923
Transcripts:ENSMUST00000022895, ENSMUST00000159221, ENSMUST00000161405, ENSMUST00000161532, ENSMUST00000161933
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF411213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC041795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY018142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY703140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ322576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000022895   ⟹   ENSMUSP00000022895
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1537,233,036 - 37,363,569 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159221   ⟹   ENSMUSP00000123871
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1537,335,737 - 37,360,940 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161405   ⟹   ENSMUSP00000125410
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1537,233,036 - 37,333,647 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161532   ⟹   ENSMUSP00000124903
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1537,233,058 - 37,279,553 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161933
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1537,318,403 - 37,363,562 (+)Ensembl
RefSeq Acc Id: ENSMUST00000228589
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1537,285,593 - 37,288,912 (+)Ensembl
RefSeq Acc Id: NM_026496   ⟹   NP_080772
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391537,233,280 - 37,363,813 (+)NCBI
GRCm381537,233,036 - 37,363,569 (+)NCBI
MGSCv371537,162,791 - 37,293,324 (+)RGD
Celera1537,856,086 - 37,983,260 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520063   ⟹   XP_006520126
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391537,233,352 - 37,363,807 (+)NCBI
GRCm381537,233,108 - 37,363,569 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006520065   ⟹   XP_006520128
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391537,233,280 - 37,333,893 (+)NCBI
GRCm381537,233,036 - 37,333,649 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316621   ⟹   XP_017172110
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391537,233,352 - 37,363,807 (+)NCBI
GRCm381537,233,108 - 37,363,569 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316622   ⟹   XP_017172111
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391537,233,065 - 37,333,893 (+)NCBI
GRCm381537,232,821 - 37,333,649 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316623   ⟹   XP_017172112
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391537,233,352 - 37,329,805 (+)NCBI
GRCm381537,233,108 - 37,329,561 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080772   ⟸   NM_026496
- UniProtKB: Q8K5C0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520128   ⟸   XM_006520065
- Peptide Label: isoform X5
- UniProtKB: Q9DCN4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006520126   ⟸   XM_006520063
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017172110   ⟸   XM_017316621
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017172111   ⟸   XM_017316622
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017172112   ⟸   XM_017316623
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSMUSP00000123871   ⟸   ENSMUST00000159221
RefSeq Acc Id: ENSMUSP00000022895   ⟸   ENSMUST00000022895
RefSeq Acc Id: ENSMUSP00000125410   ⟸   ENSMUST00000161405
RefSeq Acc Id: ENSMUSP00000124903   ⟸   ENSMUST00000161532
Protein Domains
CP2   Grh/CP2 DB

Promoters
RGD ID:6826076
Promoter ID:MM_KWN:18279
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:OTTMUST00000076417,   OTTMUST00000076418,   OTTMUST00000076420
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361537,162,496 - 37,162,996 (+)MPROMDB
RGD ID:8683608
Promoter ID:EPDNEW_M19835
Type:initiation region
Name:Grhl2_1
Description:Mus musculus grainyhead like transcription factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19836  EPDNEW_M19837  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381537,233,088 - 37,233,148EPDNEW
RGD ID:8683610
Promoter ID:EPDNEW_M19836
Type:single initiation site
Name:Grhl2_3
Description:Mus musculus grainyhead like transcription factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19835  EPDNEW_M19837  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381537,318,394 - 37,318,454EPDNEW
RGD ID:8683612
Promoter ID:EPDNEW_M19837
Type:multiple initiation site
Name:Grhl2_2
Description:Mus musculus grainyhead like transcription factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19835  EPDNEW_M19836  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381537,320,053 - 37,320,113EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2182543 AgrOrtholog
Ensembl Genes ENSMUSG00000022286 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000022895 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000123871 UniProtKB/TrEMBL
  ENSMUSP00000124903 UniProtKB/TrEMBL
  ENSMUSP00000125410 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022895 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000159221 UniProtKB/TrEMBL
  ENSMUST00000161405 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000161532 UniProtKB/TrEMBL
InterPro CP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:252973 UniProtKB/Swiss-Prot
MGD MGI:2182543 ENTREZGENE
NCBI Gene 252973 ENTREZGENE
Pfam CP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Grhl2 PhenoGen
PROSITE GRH_CP2_DB UniProtKB/Swiss-Prot
UniProt F6TZV3_MOUSE UniProtKB/TrEMBL
  F6UT30_MOUSE UniProtKB/TrEMBL
  GRHL2_MOUSE UniProtKB/Swiss-Prot
  Q3TTU6_MOUSE UniProtKB/TrEMBL
  Q8K5C0 ENTREZGENE
  Q99KA7_MOUSE UniProtKB/TrEMBL
  Q9DCN4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q80UZ5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-31 Grhl2  grainyhead like transcription factor 2    grainyhead-like 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED