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Gene: Epgn (epithelial mitogen) Mus musculus
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Symbol: Epgn
Name: epithelial mitogen
RGD ID: 1557934
Description: Exhibits epidermal growth factor receptor binding activity and growth factor activity. Involved in several processes, including MAPK cascade; positive regulation of mitotic nuclear division; and positive regulation of protein kinase activity. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in alimentary system; metanephros; skin; thymus; and trachea. Orthologous to human EPGN (epithelial mitogen); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; folic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2310069M11Rik; EPG; epi; epigen
Orthologs:
Homo sapiens (human) : EPGN (epithelial mitogen)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Epgn (epithelial mitogen)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epgn (epithelial mitogen)
Pan paniscus (bonobo/pygmy chimpanzee) : EPGN (epithelial mitogen)
Canis lupus familiaris (dog) : EPGN (epithelial mitogen)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epgn (epithelial mitogen)
Sus scrofa (pig) : EPGN (epithelial mitogen)
Chlorocebus sabaeus (African green monkey) : EPGN (epithelial mitogen)
Heterocephalus glaber (naked mole-rat) : Epgn (epithelial mitogen)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39591,175,376 - 91,183,071 (+)NCBI
GRCm38591,027,517 - 91,035,212 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl591,027,464 - 91,035,215 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,456,543 - 91,464,238 (+)NCBIGRCm37mm9NCBIm37
MGSCv36592,102,717 - 92,110,412 (+)NCBImm8
Celera589,163,266 - 89,170,925 (+)NCBICelera
Cytogenetic Map5E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Epgn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557934
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.