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Gene: Rfx2 (regulatory factor X, 2 (influences HLA class II expression)) Mus musculus
Symbol: Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to leukemia inhibitory factor; organelle assembly; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; liver; ovary; primitive streak; and sensory organ. Orthologous to human RFX2 (regulatory factor X2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430432H19Rik; DNA-binding protein RFX2; regulatory factor X 2
Homo sapiens (human) : RFX2 (regulatory factor X2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rfx2 (regulatory factor X2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx2 (regulatory factor X2)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX2 (regulatory factor X2)
Canis lupus familiaris (dog) : RFX2 (regulatory factor X2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx2 (regulatory factor X2)
Sus scrofa (pig) : RFX2 (regulatory factor X2)
Chlorocebus sabaeus (African green monkey) : RFX2 (regulatory factor X2)
Heterocephalus glaber (naked mole-rat) : Rfx2 (regulatory factor X2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1756,775,897 - 56,831,013 (-)EnsemblGRCm38mm10GRCm38
GRCm381756,775,897 - 56,831,008 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371756,915,320 - 56,970,431 (-)NCBIGRCm37mm9NCBIm37
MGSCv361756,461,169 - 56,516,087 (-)NCBImm8
Celera1761,120,038 - 61,175,702 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rfx2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557906
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.