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Gene: Rfx2 (regulatory factor X, 2 (influences HLA class II expression)) Mus musculus
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Symbol: Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to leukemia inhibitory factor; organelle assembly; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; liver; ovary; primitive streak; and sensory organ. Orthologous to human RFX2 (regulatory factor X2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430432H19Rik; DNA-binding protein RFX2; regulatory factor X 2
Orthologs:
Homo sapiens (human) : RFX2 (regulatory factor X2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rfx2 (regulatory factor X2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx2 (regulatory factor X2)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX2 (regulatory factor X2)
Canis lupus familiaris (dog) : RFX2 (regulatory factor X2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx2 (regulatory factor X2)
Sus scrofa (pig) : RFX2 (regulatory factor X2)
Chlorocebus sabaeus (African green monkey) : RFX2 (regulatory factor X2)
Heterocephalus glaber (naked mole-rat) : Rfx2 (regulatory factor X2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1756,775,897 - 56,831,013 (-)EnsemblGRCm38mm10GRCm38
GRCm381756,775,897 - 56,831,008 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371756,915,320 - 56,970,431 (-)NCBIGRCm37mm9NCBIm37
MGSCv361756,461,169 - 56,516,087 (-)NCBImm8
Celera1761,120,038 - 61,175,702 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rfx2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557906
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.