Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of ZFP277 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ZFP277 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZFP277 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ZNF277 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFP277 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZFP277 mRNA | CTD | PMID:33387578 | 2-hydroxypropanoic acid | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ZNF277 mRNA | CTD | PMID:30851411 | 6-propyl-2-thiouracil | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ZFP277 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of ZFP277 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | ZNF277 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ZNF277 gene | CTD | PMID:27153756 | aflatoxin B1 | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ZNF277 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ZNF277 mRNA | CTD | PMID:33167477 | amitrole | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of ZFP277 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ZNF277 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of ZFP277 mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | ISO | ZNF277 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to ZNF277 mRNA] | CTD | PMID:32406909 | atrazine | affects methylation | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of ZFP277 gene | CTD | PMID:35440735 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ZFP277 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ZNF277 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ZFP277 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ZFP277 mRNA | CTD | PMID:22228805 | bisphenol A | decreases methylation | ISO | ZNF277 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ZNF277 gene | CTD | PMID:31601247 | cadmium atom | multiple interactions | ISO | ZNF277 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ZNF277 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | ZNF277 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ZNF277 mRNA | CTD | PMID:35301059 | cisplatin | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ZNF277 mRNA | CTD | PMID:21603599 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of ZFP277 mRNA | CTD | PMID:21139344 | cobalt dichloride | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of ZNF277 mRNA | CTD | PMID:19320972 and PMID:19376846 | copper(II) sulfate | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ZNF277 mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of ZNF277 mRNA | CTD | PMID:19167446 | coumestrol | multiple interactions | ISO | ZNF277 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF277 mRNA | CTD | PMID:19167446 | CU-O LINKAGE | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | cupric oxide results in increased expression of ZNF277 mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ZNF277 mRNA | CTD | PMID:25562108 | dicrotophos | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of ZNF277 mRNA | CTD | PMID:28302478 | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of ZFP277 mRNA | CTD | PMID:19277126 | Enterolactone | multiple interactions | ISO | ZNF277 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF277 mRNA | CTD | PMID:19167446 | ethyl methanesulfonate | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of ZNF277 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZFP277 mRNA | CTD | PMID:22206623 | gentamycin | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of ZFP277 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Glafenine results in decreased expression of ZFP277 mRNA | CTD | PMID:24136188 | glyphosate | increases methylation | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Glyphosate results in increased methylation of ZFP277 gene | CTD | PMID:31011160 | gold atom | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Gold results in decreased expression of ZNF277 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Gold results in decreased expression of ZNF277 mRNA | CTD | PMID:25523186 | melphalan | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Melphalan results in decreased expression of ZNF277 mRNA | CTD | PMID:22363485 | methimazole | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of ZFP277 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ZNF277 mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of ZNF277 mRNA | CTD | PMID:28001369 | niclosamide | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of ZNF277 mRNA | CTD | PMID:36318118 | oxaliplatin | multiple interactions | ISO | Zfp277 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZFP277 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ZNF277 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of ZFP277 mRNA | CTD | PMID:33387578 | PCB138 | increases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ZNF277 mRNA | CTD | PMID:27153767 | propiconazole | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | propiconazole results in decreased expression of ZFP277 mRNA | CTD | PMID:30047161 | rac-lactic acid | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ZNF277 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | ZNF277 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of ZNF277 mRNA | CTD | PMID:23557933 | sodium arsenite | decreases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ZNF277 mRNA | CTD | PMID:28595984 and PMID:34032870 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of ZFP277 mRNA | CTD | PMID:21340527 | sulfadimethoxine | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of ZFP277 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ZNF277 mRNA | CTD | PMID:31533062 | thioacetamide | decreases expression | ISO | Zfp277 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ZFP277 mRNA | CTD | PMID:34492290 | topotecan | multiple interactions | ISO | Zfp277 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZFP277 mRNA | CTD | PMID:25729387 | torcetrapib | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of ZNF277 mRNA | CTD | PMID:23228038 | trichostatin A | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ZNF277 mRNA | CTD | PMID:24935251 | trichostatin A | affects expression | ISO | ZNF277 (Homo sapiens) | 6480464 | trichostatin A affects the expression of ZNF277 mRNA | CTD | PMID:28542535 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of ZFP277 mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ZNF277 mRNA | CTD | PMID:22083351 and PMID:29154799 | valproic acid | affects expression | ISO | ZNF277 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ZNF277 mRNA | CTD | PMID:25979313 | vorinostat | increases expression | ISO | ZNF277 (Homo sapiens) | 6480464 | vorinostat results in increased expression of ZNF277 mRNA | CTD | PMID:22083351 | |