Tial1 (Tia1 cytotoxic granule-associated RNA binding protein-like 1) - Rat Genome Database

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Gene: Tial1 (Tia1 cytotoxic granule-associated RNA binding protein-like 1) Mus musculus
Analyze
Symbol: Tial1
Name: Tia1 cytotoxic granule-associated RNA binding protein-like 1
RGD ID: 1557567
MGI Page MGI
Description: Enables mRNA 3'-UTR AU-rich region binding activity. Acts upstream of or within germ cell development; positive regulation of stem cell proliferation; and stem cell division. Located in cytoplasmic stress granule and nucleus. Is expressed in several structures, including branchial arch; central nervous system; primordial germ cell; sensory organ; and testis. Orthologous to human TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 5330433G13Rik; AL033329; mT; mTIAR; nucleolysin TIAR; T; TIA-1-related protein; Tial1 cytotoxic granule-associated RNA binding protein-like 1; Tial1 cytotoxic granule-associated RNA-binding protein-like 1; TIAR
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397128,041,496 - 128,063,450 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7128,041,501 - 128,063,441 (-)EnsemblGRCm39 Ensembl
GRCm387128,439,772 - 128,461,726 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,439,777 - 128,461,717 (-)EnsemblGRCm38mm10GRCm38
MGSCv377135,583,291 - 135,605,027 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367128,233,450 - 128,252,437 (-)NCBIMGSCv36mm8
Celera7128,278,008 - 128,299,764 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map770.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression of the RNA-binding protein TIAR is increased in neurons after ischemic cerebral injury. Jin K, etal., J Neurosci Res 2000 Mar 15;59(6):767-74.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Alternative splicing: a pivotal step between eukaryotic transcription and translation. Kornblihtt AR, etal., Nat Rev Mol Cell Biol. 2013 Mar;14(3):153-65. doi: 10.1038/nrm3525. Epub 2013 Feb 6.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7671812   PMID:8871565   PMID:9482885   PMID:10349636   PMID:10921895   PMID:11042159   PMID:11076861   PMID:12388085   PMID:12456657   PMID:12477932   PMID:12666202   PMID:14610273  
PMID:15371533   PMID:15782199   PMID:16033648   PMID:16141072   PMID:16141073   PMID:16278295   PMID:17074806   PMID:17349961   PMID:17488725   PMID:19110540   PMID:19339348   PMID:19805546  
PMID:19825938   PMID:19861488   PMID:20059953   PMID:20159962   PMID:20211142   PMID:20477871   PMID:20596534   PMID:21189287   PMID:21267068   PMID:21436445   PMID:21677750   PMID:22922362  
PMID:23463509   PMID:24086455   PMID:24553115   PMID:24696465   PMID:24766723   PMID:25483082   PMID:26951610   PMID:29055695   PMID:31138677   PMID:31330130   PMID:31657143   PMID:32325033  
PMID:33601422   PMID:36293380   PMID:36543128   PMID:37296170   PMID:37474714  


Genomics

Comparative Map Data
Tial1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397128,041,496 - 128,063,450 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7128,041,501 - 128,063,441 (-)EnsemblGRCm39 Ensembl
GRCm387128,439,772 - 128,461,726 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,439,777 - 128,461,717 (-)EnsemblGRCm38mm10GRCm38
MGSCv377135,583,291 - 135,605,027 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367128,233,450 - 128,252,437 (-)NCBIMGSCv36mm8
Celera7128,278,008 - 128,299,764 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map770.2NCBI
TIAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810119,573,465 - 119,596,964 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10119,571,802 - 119,597,029 (-)EnsemblGRCh38hg38GRCh38
GRCh3710121,332,977 - 121,356,476 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610121,322,967 - 121,346,531 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410121,324,903 - 121,343,015NCBI
Celera10115,063,941 - 115,087,519 (-)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10114,962,544 - 114,986,092 (-)NCBIHuRef
CHM1_110121,617,558 - 121,641,117 (-)NCBICHM1_1
T2T-CHM13v2.010120,471,044 - 120,494,540 (-)NCBIT2T-CHM13v2.0
Tial1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,438,794 - 192,475,520 (-)NCBIGRCr8
mRatBN7.21183,008,358 - 183,045,092 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,009,253 - 183,031,637 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,361,276 - 191,381,864 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01198,547,363 - 198,567,951 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01191,217,117 - 191,237,695 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,844,854 - 199,865,843 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,844,859 - 199,865,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,892,006 - 206,913,468 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,687,606 - 187,706,035 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1180,656,068 - 180,676,817 (-)NCBICelera
Cytogenetic Map1q37NCBI
Tial1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955551370,792 - 395,836 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955551370,792 - 395,836 (-)NCBIChiLan1.0ChiLan1.0
TIAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28131,432,182 - 131,453,375 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110131,433,733 - 131,458,680 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010116,142,127 - 116,165,631 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110119,561,977 - 119,585,157 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10119,561,786 - 119,585,157 (-)Ensemblpanpan1.1panPan2
TIAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12829,729,246 - 29,750,703 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2829,731,950 - 29,750,229 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2829,871,505 - 29,892,642 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02830,260,194 - 30,281,358 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2830,259,529 - 30,281,046 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12829,814,092 - 29,835,256 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02829,834,767 - 29,855,900 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02830,028,947 - 30,050,087 (-)NCBIUU_Cfam_GSD_1.0
Tial1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721316,613,431 - 16,636,073 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364868,924,738 - 8,947,877 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364868,925,819 - 8,947,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14129,441,211 - 129,467,112 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114129,441,209 - 129,467,150 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214140,967,450 - 140,991,126 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TIAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19112,355,900 - 112,379,531 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9112,358,101 - 112,379,671 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604873,628,854 - 73,652,611 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tial1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473727,236,533 - 27,259,464 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tial1
706 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2400
Count of miRNA genes:662
Interacting mature miRNAs:868
Transcripts:ENSMUST00000033135, ENSMUST00000106226, ENSMUST00000106228, ENSMUST00000123666, ENSMUST00000133089, ENSMUST00000133444, ENSMUST00000136782, ENSMUST00000141079, ENSMUST00000141126, ENSMUST00000152328, ENSMUST00000165023
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
38501072Stsl7_mSalmonella typhimurium susceptibility locus 7 (mouse)7115699235128501724Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
15092059Wogrme1_mweek one growth rate, maternal effect 1 (mouse)7117199227134101729Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1357613Bsbob2_mBSB obesity 2 (mouse)Not determined7122250663128819324Mouse
1301903Tlsm1_mthymic lymphoma susceptible 1 (mouse)Not determined7122250663135170901Mouse
4141945Il4ppq_mIL-4 producing potential QTL (mouse)Not determined7124513662128819324Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse

Markers in Region
Tial1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F4UniSTS
cM Map7 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001347640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006507571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_378230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_378231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC130474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U55861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000033135   ⟹   ENSMUSP00000033135
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,044,004 - 128,063,079 (-)Ensembl
GRCm38.p6 Ensembl7128,442,280 - 128,461,355 (-)Ensembl
RefSeq Acc Id: ENSMUST00000106226   ⟹   ENSMUSP00000101833
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,041,501 - 128,063,396 (-)Ensembl
GRCm38.p6 Ensembl7128,439,777 - 128,461,672 (-)Ensembl
RefSeq Acc Id: ENSMUST00000106228   ⟹   ENSMUSP00000101835
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,043,127 - 128,063,397 (-)Ensembl
GRCm38.p6 Ensembl7128,441,403 - 128,461,673 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123666   ⟹   ENSMUSP00000116921
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,044,004 - 128,063,441 (-)Ensembl
GRCm38.p6 Ensembl7128,442,280 - 128,461,717 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133089   ⟹   ENSMUSP00000146031
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,045,538 - 128,050,070 (-)Ensembl
GRCm38.p6 Ensembl7128,443,814 - 128,448,346 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133444   ⟹   ENSMUSP00000145943
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,043,933 - 128,046,629 (-)Ensembl
GRCm38.p6 Ensembl7128,442,209 - 128,444,905 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136782
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,049,572 - 128,050,602 (-)Ensembl
GRCm38.p6 Ensembl7128,447,848 - 128,448,878 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141079
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,041,949 - 128,063,376 (-)Ensembl
GRCm38.p6 Ensembl7128,440,225 - 128,461,652 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141126   ⟹   ENSMUSP00000145933
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,044,035 - 128,063,070 (-)Ensembl
GRCm38.p6 Ensembl7128,442,311 - 128,461,346 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,046,013 - 128,047,429 (-)Ensembl
GRCm38.p6 Ensembl7128,444,289 - 128,445,705 (-)Ensembl
RefSeq Acc Id: ENSMUST00000165023   ⟹   ENSMUSP00000126458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,043,519 - 128,063,047 (-)Ensembl
GRCm38.p6 Ensembl7128,441,795 - 128,461,323 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205278   ⟹   ENSMUSP00000145908
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,046,536 - 128,056,752 (-)Ensembl
GRCm38.p6 Ensembl7128,444,812 - 128,455,028 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205774
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,048,487 - 128,050,294 (-)Ensembl
GRCm38.p6 Ensembl7128,446,763 - 128,448,570 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205835   ⟹   ENSMUSP00000145770
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7128,044,004 - 128,062,933 (-)Ensembl
GRCm38.p6 Ensembl7128,442,280 - 128,461,209 (-)Ensembl
RefSeq Acc Id: NM_001347640   ⟹   NP_001334569
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,501 - 128,063,397 (-)NCBI
GRCm387128,439,777 - 128,461,673 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001347641   ⟹   NP_001334570
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,501 - 128,063,397 (-)NCBI
GRCm387128,439,777 - 128,461,673 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009383   ⟹   NP_033409
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,501 - 128,063,237 (-)NCBI
GRCm387128,439,777 - 128,461,513 (-)NCBI
MGSCv377135,583,291 - 135,605,027 (-)RGD
Celera7128,278,008 - 128,299,764 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006507571   ⟹   XP_006507634
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,496 - 128,063,390 (-)NCBI
GRCm387128,439,772 - 128,461,647 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017322108   ⟹   XP_017177597
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,442,274 - 128,461,652 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242346   ⟹   XP_030098206
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,442,274 - 128,461,647 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242348   ⟹   XP_030098208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,442,274 - 128,461,647 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242349   ⟹   XP_030098209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,441,982 - 128,461,353 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242350   ⟹   XP_030098210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,706 - 128,063,361 (-)NCBI
GRCm387128,441,982 - 128,461,637 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242351   ⟹   XP_030098211
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,442,274 - 128,461,647 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242352   ⟹   XP_030098212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,706 - 128,063,178 (-)NCBI
GRCm387128,441,982 - 128,461,454 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242353   ⟹   XP_030098213
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,442,274 - 128,461,647 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242354   ⟹   XP_030098214
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,998 - 128,063,390 (-)NCBI
GRCm387128,442,274 - 128,461,647 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152887   ⟹   XP_036008780
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,706 - 128,063,374 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152888   ⟹   XP_036008781
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,706 - 128,063,030 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152890   ⟹   XP_036008783
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,043,706 - 128,063,071 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004934056
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,496 - 128,063,450 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004934057
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,496 - 128,063,450 (-)NCBI
Sequence:
RefSeq Acc Id: XR_378230
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,496 - 128,063,450 (-)NCBI
GRCm387128,439,772 - 128,461,726 (-)NCBI
Sequence:
RefSeq Acc Id: XR_378231
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397128,041,496 - 128,063,450 (-)NCBI
GRCm387128,439,772 - 128,461,726 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001334569 (Get FASTA)   NCBI Sequence Viewer  
  NP_001334570 (Get FASTA)   NCBI Sequence Viewer  
  NP_033409 (Get FASTA)   NCBI Sequence Viewer  
  XP_006507634 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177597 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098206 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098208 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098209 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098210 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098211 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098212 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098213 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098214 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008780 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008781 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008783 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52870 (Get FASTA)   NCBI Sequence Viewer  
  AAH10496 (Get FASTA)   NCBI Sequence Viewer  
  AAH68194 (Get FASTA)   NCBI Sequence Viewer  
  BAB28019 (Get FASTA)   NCBI Sequence Viewer  
  BAC37623 (Get FASTA)   NCBI Sequence Viewer  
  EDL17647 (Get FASTA)   NCBI Sequence Viewer  
  EDL17648 (Get FASTA)   NCBI Sequence Viewer  
  EDL17649 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000033135
  ENSMUSP00000033135.8
  ENSMUSP00000101833
  ENSMUSP00000101833.3
  ENSMUSP00000101835
  ENSMUSP00000101835.3
  ENSMUSP00000116921.2
  ENSMUSP00000126458.2
  ENSMUSP00000145770.2
  ENSMUSP00000145908.2
  ENSMUSP00000145933
  ENSMUSP00000145933.2
  ENSMUSP00000145943.2
  ENSMUSP00000146031.2
GenBank Protein P70318 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_033409   ⟸   NM_009383
- Peptide Label: isoform 1
- UniProtKB: P70318 (UniProtKB/Swiss-Prot),   Q545C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006507634   ⟸   XM_006507571
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017177597   ⟸   XM_017322108
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334569   ⟸   NM_001347640
- Peptide Label: isoform 2
- UniProtKB: Q921W2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001334570   ⟸   NM_001347641
- Peptide Label: isoform 3
- UniProtKB: D3Z3Y4 (UniProtKB/TrEMBL),   Q6NVC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098210   ⟸   XM_030242350
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098212   ⟸   XM_030242352
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098209   ⟸   XM_030242349
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098206   ⟸   XM_030242346
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098213   ⟸   XM_030242353
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098211   ⟸   XM_030242351
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098208   ⟸   XM_030242348
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098214   ⟸   XM_030242354
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000145943   ⟸   ENSMUST00000133444
RefSeq Acc Id: ENSMUSP00000146031   ⟸   ENSMUST00000133089
RefSeq Acc Id: ENSMUSP00000145770   ⟸   ENSMUST00000205835
RefSeq Acc Id: ENSMUSP00000145908   ⟸   ENSMUST00000205278
RefSeq Acc Id: ENSMUSP00000033135   ⟸   ENSMUST00000033135
RefSeq Acc Id: ENSMUSP00000126458   ⟸   ENSMUST00000165023
RefSeq Acc Id: ENSMUSP00000101833   ⟸   ENSMUST00000106226
RefSeq Acc Id: ENSMUSP00000101835   ⟸   ENSMUST00000106228
RefSeq Acc Id: ENSMUSP00000116921   ⟸   ENSMUST00000123666
RefSeq Acc Id: ENSMUSP00000145933   ⟸   ENSMUST00000141126
RefSeq Acc Id: XP_036008780   ⟸   XM_036152887
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008783   ⟸   XM_036152890
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008781   ⟸   XM_036152888
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPD3 (UniProtKB/TrEMBL)
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70318-F1-model_v2 AlphaFold P70318 1-392 view protein structure

Promoters
RGD ID:8665769
Promoter ID:EPDNEW_M10916
Type:initiation region
Name:Tial1_1
Description:Mus musculus Tia1 cytotoxic granule-associated RNA binding protein-like1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10917  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387128,461,356 - 128,461,416EPDNEW
RGD ID:8665771
Promoter ID:EPDNEW_M10917
Type:initiation region
Name:Tial1_2
Description:Mus musculus Tia1 cytotoxic granule-associated RNA binding protein-like1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10916  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387128,461,591 - 128,461,651EPDNEW
RGD ID:6842182
Promoter ID:MM_KWN:52875
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000106228,   OTTMUST00000062612,   OTTMUST00000062614,   OTTMUST00000062616,   OTTMUST00000062618,   UC009JYZ.1,   UC009JZA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367135,604,936 - 135,605,557 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107913 AgrOrtholog
Ensembl Genes ENSMUSG00000030846 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033135 ENTREZGENE
  ENSMUST00000033135.9 UniProtKB/TrEMBL
  ENSMUST00000106226 ENTREZGENE
  ENSMUST00000106226.9 UniProtKB/Swiss-Prot
  ENSMUST00000106228 ENTREZGENE
  ENSMUST00000106228.8 UniProtKB/TrEMBL
  ENSMUST00000123666.8 UniProtKB/TrEMBL
  ENSMUST00000133089.8 UniProtKB/TrEMBL
  ENSMUST00000133444.8 UniProtKB/TrEMBL
  ENSMUST00000141126 ENTREZGENE
  ENSMUST00000141126.8 UniProtKB/TrEMBL
  ENSMUST00000165023.8 UniProtKB/TrEMBL
  ENSMUST00000205278.2 UniProtKB/TrEMBL
  ENSMUST00000205835.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIAR_RRM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIAR_RRM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIAR_RRM3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21843 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107913 ENTREZGENE
NCBI Gene 21843 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G UniProtKB/TrEMBL
  HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEOLYSIN TIAR UniProtKB/TrEMBL
  OS02G0815200 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBONUCLEOPROTEIN RB97D UniProtKB/TrEMBL
  RIBONUCLEOPROTEIN RB97D UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tial1 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RP00_MOUSE UniProtKB/TrEMBL
  A0A0U1RPB0_MOUSE UniProtKB/TrEMBL
  A0A0U1RPD3 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RPE1_MOUSE UniProtKB/TrEMBL
  A0A0U1RPL4_MOUSE UniProtKB/TrEMBL
  D3Z3Y4 ENTREZGENE, UniProtKB/TrEMBL
  D6RGU1_MOUSE UniProtKB/TrEMBL
  P70318 ENTREZGENE
  Q545C1 ENTREZGENE, UniProtKB/TrEMBL
  Q6NVC2 ENTREZGENE, UniProtKB/TrEMBL
  Q8C573_MOUSE UniProtKB/TrEMBL
  Q921W2 ENTREZGENE, UniProtKB/TrEMBL
  TIAR_MOUSE UniProtKB/Swiss-Prot