Tas2r118 (taste receptor, type 2, member 118) - Rat Genome Database

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Gene: Tas2r118 (taste receptor, type 2, member 118) Mus musculus
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Symbol: Tas2r118
Name: taste receptor, type 2, member 118
RGD ID: 1557525
MGI Page MGI
Description: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in endoplasmic reticulum; external side of plasma membrane; and trans-Golgi network. Predicted to be integral component of membrane. Is expressed in circumvallate papilla; colon; and jejunum. Orthologous to human TAS2R16 (taste 2 receptor member 16); INTERACTS WITH dextran sulfate; titanium dioxide; acrylamide (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: candidate taste receptor mt2r40; Gm465; MGC129507; mGR1; mGR18; mt2r4; mt2r40; T2R1; T2R16; T2R18; Tas2; Tas2r16; Tas2r18; taste receptor type 2 member 16
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,969,160 - 23,970,059 (-)NCBIGRCm39mm39
GRCm39 Ensembl623,969,160 - 23,970,059 (-)Ensembl
GRCm38623,969,161 - 23,970,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,969,161 - 23,970,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv37623,919,161 - 23,920,060 (-)NCBIGRCm37mm9NCBIm37
MGSCv36623,919,163 - 23,920,062 (-)NCBImm8
Celera623,993,940 - 23,994,839 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:11696554   PMID:11854532   PMID:12139982   PMID:12477932   PMID:12581520   PMID:12679530   PMID:12734386   PMID:15489334   PMID:21873635   PMID:24367558  


Genomics

Comparative Map Data
Tas2r118
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,969,160 - 23,970,059 (-)NCBIGRCm39mm39
GRCm39 Ensembl623,969,160 - 23,970,059 (-)Ensembl
GRCm38623,969,161 - 23,970,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,969,161 - 23,970,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv37623,919,161 - 23,920,060 (-)NCBIGRCm37mm9NCBIm37
MGSCv36623,919,163 - 23,920,062 (-)NCBImm8
Celera623,993,940 - 23,994,839 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
TAS2R16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7122,994,704 - 122,995,700 (-)EnsemblGRCh38hg38GRCh38
GRCh387122,994,704 - 122,995,700 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377122,634,758 - 122,635,754 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367122,421,995 - 122,422,990 (-)NCBINCBI36hg18NCBI36
Build 347122,228,763 - 122,229,639NCBI
Celera7117,439,504 - 117,440,499 (-)NCBI
Cytogenetic Map7q31.32NCBI
HuRef7116,997,714 - 116,998,709 (-)NCBIHuRef
CHM1_17122,568,066 - 122,569,061 (-)NCBICHM1_1
CRA_TCAGchr7v27122,023,644 - 122,024,639 (-)NCBI
Tas2r118
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2452,449,208 - 52,450,107 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl452,449,208 - 52,450,107 (-)Ensembl
Rnor_6.0451,002,218 - 51,003,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl451,002,218 - 51,003,117 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0450,781,192 - 50,782,091 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4450,342,537 - 50,343,436 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1450,573,110 - 50,574,010 (-)NCBI
Celera447,635,254 - 47,636,153 (-)NCBICelera
Cytogenetic Map4q22NCBI
Tas2r16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554794,591,015 - 4,591,920 (-)NCBIChiLan1.0ChiLan1.0
TAS2R16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17127,687,850 - 127,688,834 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7127,687,899 - 127,688,774 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07115,003,966 - 115,004,950 (-)NCBIMhudiblu_PPA_v0panPan3
Tas2r16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511849,804,785 - 49,805,690 (-)NCBI
SpeTri2.0NW_0049366052,398,240 - 2,399,145 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAS2R16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1824,286,430 - 24,287,332 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11824,281,944 - 24,290,222 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21825,883,118 - 25,884,436 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAS2R16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12191,781,827 - 91,785,831 (-)NCBI
ChlSab1.1 Ensembl2191,783,091 - 91,783,963 (-)Ensembl
Vero_WHO_p1.0NW_02366604211,700,462 - 11,701,899 (+)NCBI
Tas2r16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478312,993,230 - 12,994,135 (+)NCBI

Position Markers
UniSTS:490633  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38623,969,161 - 23,970,060UniSTSGRCm38
MGSCv37623,919,161 - 23,920,060UniSTSGRCm37
Celera623,993,940 - 23,994,839UniSTS
Cytogenetic Map6A3.1UniSTS
UniSTS:493143  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38623,969,161 - 23,970,060UniSTSGRCm38
MGSCv37623,919,161 - 23,920,060UniSTSGRCm37
Celera623,993,940 - 23,994,839UniSTS
Cytogenetic Map6A3.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12904934Edlmmq4_mextensor digitorum longus muscle mass QTL 4 (mouse)6125514064Mouse
12904942Tammq3_mtibialis anterior muscle mass QTL 3 (mouse)6125514064Mouse
12904955Gmmq3_mgastrocnemius muscle mass QTL 3 (mouse)6125514064Mouse
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144496Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144496Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144496Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633535476335Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920738249326Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
11353836Bmiq1_mbody mass index QTL 1 (mouse)6450382329751334Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345314181Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348726677Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348726677Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348726677Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707543297169Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797246118070Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122246751334Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122246751334Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61770000053500000Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61773466351734784Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1773466351734784Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61773466351734784Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61963941153639411Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61963941153639411Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61963941153639411Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268671322775Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62007289554072895Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62380000057800000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:79
Interacting mature miRNAs:80
Transcripts:ENSMUST00000062463
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000062463   ⟹   ENSMUSP00000053700
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl623,969,160 - 23,970,059 (-)Ensembl
GRCm38.p6 Ensembl623,969,161 - 23,970,060 (-)Ensembl
RefSeq Acc Id: NM_207022   ⟹   NP_996905
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39623,969,160 - 23,970,059 (-)NCBI
GRCm38623,969,161 - 23,970,060 (-)ENTREZGENE
MGSCv37623,919,161 - 23,920,060 (-)RGD
Celera623,993,940 - 23,994,839 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_996905 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI04401 (Get FASTA)   NCBI Sequence Viewer  
  AAI04402 (Get FASTA)   NCBI Sequence Viewer  
  DAA01208 (Get FASTA)   NCBI Sequence Viewer  
  P59529 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_996905   ⟸   NM_207022
- UniProtKB: P59529 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000053700   ⟸   ENSMUST00000062463


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2681247 AgrOrtholog
Ensembl Genes ENSMUSG00000043865 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000053700 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000062463 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro T2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:387347 UniProtKB/Swiss-Prot
MGD MGI:2681247 ENTREZGENE
NCBI Gene 387347 ENTREZGENE
Pfam TAS2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tas2r118 PhenoGen
UniProt A0AUK2_MOUSE UniProtKB/TrEMBL
  P59529 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q7M728 UniProtKB/Swiss-Prot