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Gene: Plcb2 (phospholipase C, beta 2) Mus musculus
Symbol: Plcb2
Name: phospholipase C, beta 2
Description: Predicted to have G-protein beta/gamma-subunit complex binding activity; phosphatidylinositol phospholipase C activity; and phospholipid binding activity. Involved in sensory perception of bitter taste. Localizes to the cytoplasm. Is expressed in several structures, including early conceptus; genitourinary system; gut; immune system; and liver. Orthologous to human PLCB2 (phospholipase C beta 2); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dextran sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; AI550384; B230205M18Rik; B230399N12; phosphoinositide phospholipase C-beta-2; phospholipase C-beta-2; PLC-beta-2
Homo sapiens (human) : PLCB2 (phospholipase C beta 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcb2 (phospholipase C, beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb2 (phospholipase C beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB2 (phospholipase C beta 2)
Canis lupus familiaris (dog) : PLCB2 (phospholipase C beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb2 (phospholipase C beta 2)
Sus scrofa (pig) : PLCB2 (phospholipase C beta 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2118,707,517 - 118,728,438 (-)Ensembl
GRCm382118,705,003 - 118,728,661 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372118,533,253 - 118,554,174 (-)NCBIGRCm37mm9NCBIm37
MGSCv362118,398,958 - 118,419,879 (-)NCBImm8
Celera2119,861,823 - 119,882,734 (-)NCBICelera
Cytogenetic Map2 E5NCBI
cM Map259.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Plcb2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557476
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.