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Gene: Sergef (secretion regulating guanine nucleotide exchange factor) Mus musculus
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Symbol: Sergef
Name: secretion regulating guanine nucleotide exchange factor
RGD ID: 1557264
Description: Predicted to have Ran guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of protein secretion. Localizes to cytoplasm and nucleus. Is expressed in central nervous system; esophagus; and ganglia. Orthologous to human SERGEF (secretion regulating guanine nucleotide exchange factor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deafness locus-associated putative guanine nucleotide exchange factor; DelGE; DelGEF; Gef; Gne; Gnef; Gnefr; guanine nucleotide exchange factor (RCC1 related); guanine nucleotide exchange factor-related protein; MGC141208; MGC141209; secretion-regulating guanine nucleotide exchange factor
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl746,443,154 - 46,639,807 (-)EnsemblGRCm38mm10GRCm38
GRCm38746,443,159 - 46,642,896 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37753,698,529 - 53,895,177 (-)NCBIGRCm37mm9NCBIm37
MGSCv36746,311,215 - 46,507,832 (-)NCBImm8
Celera741,916,678 - 42,113,981 (-)NCBICelera
Cytogenetic Map7B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sergef
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557264
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.