Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of DTX3L mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of DTX3L mRNA | CTD | PMID:28960355 | 17beta-estradiol | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Estradiol results in increased expression of DTX3L mRNA | CTD | PMID:21185374 | 17beta-estradiol | increases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of DTX3L mRNA | CTD | PMID:35192832 | 17beta-estradiol | multiple interactions | ISO | Dtx3l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of DTX3L mRNA | CTD | PMID:26496021 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DTX3L mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DTX3L mRNA | CTD | PMID:33387578 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of DTX3L mRNA | CTD | PMID:25172293 | acetamide | affects expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | acetamide affects the expression of DTX3L mRNA | CTD | PMID:31881176 | all-trans-retinoic acid | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Tretinoin results in increased expression of DTX3L mRNA | CTD | PMID:33167477 | atrazine | increases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Atrazine results in increased expression of DTX3L mRNA | CTD | PMID:36841081 | belinostat | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | belinostat results in decreased expression of DTX3L mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of DTX3L mRNA | CTD | PMID:23735875 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of DTX3L exon | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of DTX3L mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | ISO | Dtx3l (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of DTX3L mRNA | CTD | PMID:26496021 | bisphenol A | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | bisphenol A results in increased expression of DTX3L mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | ISO | Dtx3l (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of DTX3L gene | CTD | PMID:28505145 | bisphenol A | affects expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of DTX3L mRNA | CTD | PMID:25181051 | butanal | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of DTX3L mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DTX3L mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DTX3L mRNA | CTD | PMID:37325564 | caffeine | decreases phosphorylation | ISO | DTX3L (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of DTX3L protein | CTD | PMID:35688186 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | copper(II) sulfate | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of DTX3L mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DTX3L mRNA | CTD | PMID:25562108 | dicrotophos | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | dicrotophos results in increased expression of DTX3L mRNA | CTD | PMID:28302478 | diethyl maleate | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | diethyl maleate results in decreased expression of DTX3L mRNA | CTD | PMID:21161181 | diethylstilbestrol | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of DTX3L mRNA | CTD | PMID:36621641 | dioxygen | multiple interactions | ISO | Dtx3l (Rattus norvegicus) | 6480464 | [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of DTX3L mRNA] and [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of DTX3L mRNA | CTD | PMID:33729688 | doxorubicin | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DTX3L mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of DTX3L mRNA | CTD | PMID:29391264 | ethyl methanesulfonate | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of DTX3L mRNA | CTD | PMID:23649840 | fipronil | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | fipronil results in decreased expression of DTX3L mRNA | CTD | PMID:34044035 | formaldehyde | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of DTX3L mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | DTX3L (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DTX3L protein | CTD | PMID:37730182 | furan | increases methylation | ISO | Dtx3l (Rattus norvegicus) | 6480464 | furan results in increased methylation of DTX3L gene | CTD | PMID:22079235 | gentamycin | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of DTX3L mRNA | CTD | PMID:33387578 | hydroquinone | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | hydroquinone results in decreased expression of DTX3L mRNA | CTD | PMID:31256213 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DTX3L mRNA | CTD | PMID:36331819 | Licochalcone B | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of DTX3L mRNA | CTD | PMID:33647349 | lipopolysaccharide | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of DTX3L mRNA and Lipopolysaccharides results in increased expression of DTX3L protein | CTD | PMID:30501627 and PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | DTX3L (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of DTX3L mRNA | CTD | PMID:35811015 | methapyrilene | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of DTX3L mRNA | CTD | PMID:30467583 | methylparaben | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | methylparaben results in decreased expression of DTX3L mRNA | CTD | PMID:31745603 | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of DTX3L mRNA | CTD | PMID:27776689 | nickel atom | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Nickel results in decreased expression of DTX3L mRNA | CTD | PMID:23195993 | nickel atom | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Nickel results in increased expression of DTX3L mRNA | CTD | PMID:24768652 and PMID:25583101 | oxaliplatin | multiple interactions | ISO | Dtx3l (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of DTX3L mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DTX3L mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of DTX3L mRNA | CTD | PMID:33387578 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of DTX3L mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of DTX3L mRNA more ... | CTD | PMID:36331819 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | DTX3L (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of DTX3L mRNA | CTD | PMID:35811015 | silver atom | decreases expression | EXP | | 6480464 | Silver results in decreased expression of DTX3L mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | EXP | | 6480464 | Silver results in decreased expression of DTX3L mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of DTX3L mRNA | CTD | PMID:21795629 | sodium arsenite | increases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | sodium arsenite results in increased expression of DTX3L protein | CTD | PMID:29459688 | Soman | increases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Soman results in increased expression of DTX3L mRNA | CTD | PMID:19281266 | sunitinib | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DTX3L mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of DTX3L mRNA | CTD | PMID:31150632 | topotecan | multiple interactions | ISO | Dtx3l (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of DTX3L mRNA | CTD | PMID:25729387 | topotecan | increases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | Topotecan results in increased expression of DTX3L mRNA | CTD | PMID:25729387 | triclosan | increases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Triclosan results in increased expression of DTX3L mRNA | CTD | PMID:30510588 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of DTX3L mRNA | CTD | PMID:30912803 | urethane | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Urethane results in decreased expression of DTX3L mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DTX3L mRNA | CTD | PMID:29154799 | valproic acid | decreases methylation | ISO | DTX3L (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of DTX3L gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | DTX3L (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DTX3L mRNA | CTD | PMID:25979313 | vancomycin | decreases expression | EXP | | 6480464 | Vancomycin results in decreased expression of DTX3L mRNA | CTD | PMID:18930951 | vinclozolin | increases expression | ISO | Dtx3l (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of DTX3L mRNA | CTD | PMID:22570695 | vorinostat | decreases expression | ISO | DTX3L (Homo sapiens) | 6480464 | vorinostat results in decreased expression of DTX3L mRNA | CTD | PMID:27188386 | zidovudine | multiple interactions | ISO | DTX3L (Homo sapiens) | 6480464 | [Zidovudine co-treated with IFNA1 protein] results in increased expression of DTX3L mRNA | CTD | PMID:20370541 | |