Zfp879 (zinc finger protein 879) - Rat Genome Database

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Gene: Zfp879 (zinc finger protein 879) Mus musculus
Analyze
Symbol: Zfp879
Name: zinc finger protein 879
RGD ID: 1557181
MGI Page MGI
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; embryo mesenchyme; genitourinary system; and limb segment. Orthologous to human ZNF879 (zinc finger protein 879).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9630041N07Rik; novel zinc finger protein; RP23-292E3.2; zinc figer protein 879; Znf879
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,719,821 - 50,732,414 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,722,858 - 50,732,379 (-)EnsemblGRCm39 Ensembl
GRCm381150,828,994 - 50,841,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,832,031 - 50,841,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv371150,645,537 - 50,655,054 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,675,458 - 50,684,975 (-)NCBIMGSCv36mm8
Celera1155,394,144 - 55,403,662 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18287559   PMID:20059953  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:30973865  


Genomics

Comparative Map Data
Zfp879
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,719,821 - 50,732,414 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,722,858 - 50,732,379 (-)EnsemblGRCm39 Ensembl
GRCm381150,828,994 - 50,841,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,832,031 - 50,841,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv371150,645,537 - 50,655,054 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,675,458 - 50,684,975 (-)NCBIMGSCv36mm8
Celera1155,394,144 - 55,403,662 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.93NCBI
ZNF879
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,023,804 - 179,035,064 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,023,804 - 179,035,064 (+)EnsemblGRCh38hg38GRCh38
GRCh375178,450,805 - 178,462,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365178,383,069 - 178,394,671 (+)NCBINCBI36Build 36hg18NCBI36
Celera5174,078,027 - 174,088,704 (+)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,177,961 - 173,188,909 (+)NCBIHuRef
CHM1_15177,883,985 - 177,894,596 (+)NCBICHM1_1
T2T-CHM13v2.05179,576,953 - 179,588,262 (+)NCBIT2T-CHM13v2.0
Zfp879
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,649,693 - 35,659,692 (-)NCBIGRCr8
mRatBN7.21035,148,679 - 35,158,674 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1035,148,679 - 35,158,674 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,831,210 - 39,841,220 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01039,322,262 - 39,331,533 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,824,878 - 34,834,901 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01036,326,633 - 36,336,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1036,326,633 - 36,336,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,097,634 - 36,107,629 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41036,402,500 - 36,412,495 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1034,507,898 - 34,517,893 (-)NCBICelera
Cytogenetic Map10q22NCBI
Znf879
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554081,376,117 - 1,405,204 (-)NCBIChiLan1.0ChiLan1.0
ZNF879
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24173,967,477 - 173,978,173 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,107,011 - 172,117,713 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,184,543 - 174,195,297 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15181,475,475 - 181,486,734 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5181,474,353 - 181,486,734 (+)Ensemblpanpan1.1panPan2
ZNF879
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12380,779,700 - 80,790,970 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607512,135,175 - 12,146,055 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf879
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473342,014,657 - 42,026,102 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp879
397 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:380
Count of miRNA genes:113
Interacting mature miRNAs:125
Transcripts:ENSMUST00000049625, ENSMUST00000109133, ENSMUST00000109134
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000049625   ⟹   ENSMUSP00000061782
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,722,862 - 50,732,379 (-)Ensembl
GRCm38.p6 Ensembl1150,832,035 - 50,841,552 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109133   ⟹   ENSMUSP00000104761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,722,910 - 50,732,373 (-)Ensembl
GRCm38.p6 Ensembl1150,832,083 - 50,841,546 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109134   ⟹   ENSMUSP00000104762
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,722,858 - 50,732,379 (-)Ensembl
GRCm38.p6 Ensembl1150,832,031 - 50,841,552 (-)Ensembl
RefSeq Acc Id: NM_001290779   ⟹   NP_001277708
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,722,858 - 50,732,379 (-)NCBI
GRCm381150,832,031 - 50,841,552 (-)NCBI
Celera1155,394,140 - 55,403,662 (-)NCBI
Sequence:
RefSeq Acc Id: NM_173387   ⟹   NP_775563
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,722,858 - 50,732,379 (-)NCBI
GRCm381150,832,031 - 50,841,552 (-)NCBI
MGSCv371150,645,537 - 50,655,054 (-)RGD
Celera1155,394,140 - 55,403,662 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030245779   ⟹   XP_030101639
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,719,821 - 50,732,414 (-)NCBI
GRCm381150,828,994 - 50,841,587 (-)NCBI
Sequence:
RefSeq Acc Id: NP_775563   ⟸   NM_173387
- Peptide Label: isoform 1
- UniProtKB: Q8BI99 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277708   ⟸   NM_001290779
- Peptide Label: isoform 2
- UniProtKB: Q147Z4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101639   ⟸   XM_030245779
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000061782   ⟸   ENSMUST00000049625
RefSeq Acc Id: ENSMUSP00000104761   ⟸   ENSMUST00000109133
RefSeq Acc Id: ENSMUSP00000104762   ⟸   ENSMUST00000109134
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BI99-F1-model_v2 AlphaFold Q8BI99 1-563 view protein structure

Promoters
RGD ID:6822508
Promoter ID:MM_KWN:7264
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver
Transcripts:ENSMUST00000109133,   ENSMUST00000109134,   NM_173387
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361150,654,706 - 50,655,206 (-)MPROMDB
RGD ID:8674522
Promoter ID:EPDNEW_M15292
Type:initiation region
Name:Zfp879_1
Description:Mus musculus zinc finger protein 879 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381150,841,512 - 50,841,572EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3053099 AgrOrtholog
Ensembl Genes ENSMUSG00000044296 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000049625 ENTREZGENE
  ENSMUST00000049625.2 UniProtKB/Swiss-Prot
  ENSMUST00000109133 ENTREZGENE
  ENSMUST00000109133.2 UniProtKB/TrEMBL
  ENSMUST00000109134.8 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro KRAB UniProtKB/Swiss-Prot
  KRAB_dom_sf UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:214779 UniProtKB/Swiss-Prot
MGD MGI:3053099 ENTREZGENE
NCBI Gene 214779 ENTREZGENE
PANTHER NOVEL KRAB BOX AND ZINC FINGER, C2H2 TYPE DOMAIN CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 200 UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 436 UniProtKB/Swiss-Prot
Pfam KRAB UniProtKB/Swiss-Prot
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-H2C2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Zfp879 PhenoGen
PROSITE KRAB UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q147Z4 ENTREZGENE, UniProtKB/TrEMBL
  Q8BI99 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-15 Zfp879  zinc finger protein 879  Zfp879  zinc figer protein 879  Symbol and/or name change 5135510 APPROVED