Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Experimental Liver Cirrhosis | | ISO | MIS12 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25380136 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Experimental Liver Cirrhosis | | ISO | MIS12 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25380136 | |
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# | Reference Title | Reference Citation |
1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
2. | Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. | Ko MS, etal., Development 2000 Apr;127(8):1737-49. |
3. | MGDs mouse GO annotations | MGD data from the GO Consortium |
4. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:10349636 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:12477932 | PMID:12520002 | PMID:14610273 | PMID:15489334 | PMID:16141072 | PMID:16141073 | PMID:17967808 | PMID:18799693 |
PMID:20360068 | PMID:21633384 | PMID:21677750 | PMID:21873635 | PMID:23418356 | PMID:26496610 | PMID:32341029 |
Mis12 (Mus musculus - house mouse) |
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MIS12 (Homo sapiens - human) |
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Mis12 (Rattus norvegicus - Norway rat) |
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Mis12 (Chinchilla lanigera - long-tailed chinchilla) |
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MIS12 (Pan paniscus - bonobo/pygmy chimpanzee) |
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MIS12 (Canis lupus familiaris - dog) |
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Mis12 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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MIS12 (Sus scrofa - pig) |
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MIS12 (Chlorocebus sabaeus - green monkey) |
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Mis12 (Heterocephalus glaber - naked mole-rat) |
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Variants in Mis12
18 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
AU044651 |
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RefSeq Transcripts | NM_025993 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006533968 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006533969 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AK010995 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AK077702 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK132010 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK139957 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK154531 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AL596136 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC026790 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH466596 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CR936847 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSMUST00000048807 ⟹ ENSMUSP00000039500 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000133413 ⟹ ENSMUSP00000123291 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000136137 ⟹ ENSMUSP00000121057 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000143762 ⟹ ENSMUSP00000115256 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000155236 ⟹ ENSMUSP00000116762 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000164220 ⟹ ENSMUSP00000127782 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_025993 ⟹ NP_080269 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006533968 ⟹ XP_006534031 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006533969 ⟹ XP_006534032 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_080269 | (Get FASTA) | NCBI Sequence Viewer |
XP_006534031 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006534032 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH26790 | (Get FASTA) | NCBI Sequence Viewer |
BAB27314 | (Get FASTA) | NCBI Sequence Viewer | |
BAE20937 | (Get FASTA) | NCBI Sequence Viewer | |
BAE24195 | (Get FASTA) | NCBI Sequence Viewer | |
BAE32656 | (Get FASTA) | NCBI Sequence Viewer | |
EDL12641 | (Get FASTA) | NCBI Sequence Viewer | |
EDL12642 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSMUSP00000039500 | ||
ENSMUSP00000039500.6 | |||
ENSMUSP00000116762.2 | |||
ENSMUSP00000121057.2 | |||
ENSMUSP00000123291.2 | |||
ENSMUSP00000127782.2 | |||
GenBank Protein | Q9CY25 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_080269 ⟸ NM_025993 |
- UniProtKB: | Q5QNU8 (UniProtKB/Swiss-Prot), Q5QNU7 (UniProtKB/Swiss-Prot), Q3V261 (UniProtKB/Swiss-Prot), Q5QNU9 (UniProtKB/Swiss-Prot), Q9CY25 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006534031 ⟸ XM_006533968 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q5QNU8 (UniProtKB/Swiss-Prot), Q5QNU7 (UniProtKB/Swiss-Prot), Q3V261 (UniProtKB/Swiss-Prot), Q5QNU9 (UniProtKB/Swiss-Prot), Q9CY25 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006534032 ⟸ XM_006533969 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q5QNU8 (UniProtKB/Swiss-Prot), Q5QNU7 (UniProtKB/Swiss-Prot), Q3V261 (UniProtKB/Swiss-Prot), Q5QNU9 (UniProtKB/Swiss-Prot), Q9CY25 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | ENSMUSP00000127782 ⟸ ENSMUST00000164220 |
RefSeq Acc Id: | ENSMUSP00000115256 ⟸ ENSMUST00000143762 |
RefSeq Acc Id: | ENSMUSP00000123291 ⟸ ENSMUST00000133413 |
RefSeq Acc Id: | ENSMUSP00000039500 ⟸ ENSMUST00000048807 |
RefSeq Acc Id: | ENSMUSP00000121057 ⟸ ENSMUST00000136137 |
RefSeq Acc Id: | ENSMUSP00000116762 ⟸ ENSMUST00000155236 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9CY25-F1-model_v2 | AlphaFold | Q9CY25 | 1-206 | view protein structure |
RGD ID: | 6820715 | ||||||||
Promoter ID: | MM_KWN:8272 | ||||||||
Type: | CpG-Island | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | 3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen | ||||||||
Transcripts: | OTTMUST00000013718, OTTMUST00000013720, OTTMUST00000013721, OTTMUST00000013722, OTTMUST00000013723, OTTMUST00000013724, OTTMUST00000013725, OTTMUST00000013727, OTTMUST00000013728, OTTMUST00000013729, UC007JXI.1, UC007JXK.1, UC007JXL.1, UC007JXN.1 | ||||||||
Position: |
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RGD ID: | 8675390 | ||||||||
Promoter ID: | EPDNEW_M15726 | ||||||||
Type: | initiation region | ||||||||
Name: | Mis12_1 | ||||||||
Description: | Mus musculus MIS12 kinetochore complex component , mRNA. | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_M15728 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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RGD ID: | 8675396 | ||||||||
Promoter ID: | EPDNEW_M15728 | ||||||||
Type: | initiation region | ||||||||
Name: | Mis12_2 | ||||||||
Description: | Mus musculus MIS12 kinetochore complex component , mRNA. | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_M15726 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | MGI:1914389 | AgrOrtholog |
Ensembl Genes | ENSMUSG00000040599 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSMUST00000048807 | ENTREZGENE |
ENSMUST00000048807.12 | UniProtKB/Swiss-Prot | |
ENSMUST00000133413.8 | UniProtKB/TrEMBL | |
ENSMUST00000136137.2 | UniProtKB/TrEMBL | |
ENSMUST00000155236.2 | UniProtKB/TrEMBL | |
ENSMUST00000164220.8 | UniProtKB/Swiss-Prot | |
InterPro | Centromere_Mis12 | UniProtKB/Swiss-Prot |
KEGG Report | mmu:67139 | UniProtKB/Swiss-Prot |
MGD | MGI:1914389 | ENTREZGENE |
NCBI Gene | 67139 | ENTREZGENE |
PANTHER | PROTEIN MIS12 HOMOLOG | UniProtKB/Swiss-Prot |
PTHR14527 | UniProtKB/Swiss-Prot | |
Pfam | Mis12 | UniProtKB/Swiss-Prot |
PhenoGen | Mis12 | PhenoGen |
UniProt | A0A0G2JDA2_MOUSE | UniProtKB/TrEMBL |
A3QK65_MOUSE | UniProtKB/TrEMBL | |
A3QK66_MOUSE | UniProtKB/TrEMBL | |
MIS12_MOUSE | UniProtKB/Swiss-Prot | |
Q3V261 | ENTREZGENE | |
Q5QNU7 | ENTREZGENE | |
Q5QNU8 | ENTREZGENE | |
Q5QNU9 | ENTREZGENE | |
Q9CY25 | ENTREZGENE | |
UniProt Secondary | Q3V261 | UniProtKB/Swiss-Prot |
Q5QNU7 | UniProtKB/Swiss-Prot | |
Q5QNU8 | UniProtKB/Swiss-Prot | |
Q5QNU9 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2016-02-17 | Mis12 | MIS12 kinetochore complex component | MIS12 homolog (yeast) | Symbol and/or name change | 5135510 | APPROVED |