Ubqln5 (ubiquilin 5) - Rat Genome Database

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Gene: Ubqln5 (ubiquilin 5) Mus musculus
Analyze
No known orthologs.
Symbol: Ubqln5
Name: ubiquilin 5
RGD ID: 1556973
MGI Page MGI
Description: Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Located in mitochondrion. Is expressed in olfactory epithelium.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4931431F19Rik; hypothetical protein LOC70980; RIKEN cDNA 4931431F19 gene; ubiquilin 1-like; ubiquilin-3
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397103,777,120 - 103,779,030 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7103,777,119 - 103,779,033 (-)EnsemblGRCm39 Ensembl
GRCm387104,127,913 - 104,129,823 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7104,127,912 - 104,129,826 (-)EnsemblGRCm38mm10GRCm38
MGSCv377111,276,423 - 111,278,337 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367104,001,733 - 104,003,644 (-)NCBIMGSCv36mm8
Celera7104,508,987 - 104,510,901 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map754.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA)
mitochondrion  (HDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:24674348   PMID:31201419  


Genomics

Variants

.
Variants in Ubqln5
38 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:123
Interacting mature miRNAs:128
Transcripts:ENSMUST00000053743
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
13464255Ifvrq2_minfluenza virus resistance QTL 2 (mouse)792500698106455693Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000053743   ⟹   ENSMUSP00000062054
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7103,777,119 - 103,779,033 (-)Ensembl
GRCm38.p6 Ensembl7104,127,912 - 104,129,826 (-)Ensembl
RefSeq Acc Id: NM_027634   ⟹   NP_081910
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397103,777,120 - 103,779,030 (-)NCBI
GRCm387104,127,913 - 104,129,823 (-)ENTREZGENE
Celera7104,508,991 - 104,510,901 (-)ENTREZGENE
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_081910 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB30272 (Get FASTA)   NCBI Sequence Viewer  
  EDL16710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000062054
  ENSMUSP00000062054.5
RefSeq Acc Id: NP_081910   ⟸   NM_027634
- UniProtKB: Q9D4I8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000062054   ⟸   ENSMUST00000053743
Protein Domains
UBA   Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D4I8-F1-model_v2 AlphaFold Q9D4I8 1-510 view protein structure

Promoters
RGD ID:8665057
Promoter ID:EPDNEW_M10560
Type:multiple initiation site
Name:Ubqln5_1
Description:Mus musculus ubiquilin 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387104,129,811 - 104,129,871EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918230 AgrOrtholog
Ensembl Genes ENSMUSG00000055643 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000053743 ENTREZGENE
  ENSMUST00000053743.6 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquilin UniProtKB/TrEMBL
  Ubiquitin UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report mmu:70980 UniProtKB/TrEMBL
MGD MGI:1918230 ENTREZGENE
NCBI Gene 70980 ENTREZGENE
PANTHER UBIQUILIN UniProtKB/TrEMBL
  UBIQUILIN 5 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  ubiquitin UniProtKB/TrEMBL
PhenoGen Ubqln5 PhenoGen
PROSITE UBA UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/TrEMBL
SMART UBA UniProtKB/TrEMBL
  UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  UBA_like UniProtKB/TrEMBL
UniProt Q9D4I8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-04 Ubqln5  ubiquilin 5  4931431F19Rik  RIKEN cDNA 4931431F19 gene  Symbol and/or name change 5135510 APPROVED