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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | RGD:1323318 | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of LRRC2 mRNA | CTD | PMID:24763279 | 1-naphthyl isothiocyanate | increases expression | ISO | RGD:1311716 | 6480464 | 1-Naphthylisothiocyanate results in increased expression of LRRC2 mRNA | CTD | PMID:30723492 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of LRRC2 mRNA | CTD | PMID:15251184 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1311716 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRRC2 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1323318 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRRC2 mRNA | CTD | PMID:30096437 | 5-aza-2'-deoxycytidine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Decitabine] results in increased expression of LRRC2 mRNA | CTD | PMID:15251184 | 5-aza-2'-deoxycytidine | increases expression | EXP | | 6480464 | Decitabine results in increased expression of LRRC2 mRNA | CTD | PMID:15251184 | 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:1323318 | 6480464 | Decitabine affects the expression of LRRC2 mRNA | CTD | PMID:17145863 | 6-propyl-2-thiouracil | increases expression | ISO | RGD:1311716 | 6480464 | Propylthiouracil results in increased expression of LRRC2 mRNA | CTD | PMID:24780913, PMID:25825206 | acrylamide | decreases expression | ISO | RGD:1311716 | 6480464 | Acrylamide results in decreased expression of LRRC2 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | ISO | RGD:1323318 | 6480464 | Aflatoxin B1 results in decreased expression of LRRC2 mRNA | CTD | PMID:27153756 | aflatoxin B1 | increases methylation | ISO | RGD:1323318 | 6480464 | Aflatoxin B1 results in increased methylation of LRRC2 3' UTR | CTD | PMID:30157460 | aldrin | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzoapyrene results in decreased expression of LRRC2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | RGD:1323318 | 6480464 | Benzoapyrene results in decreased expression of LRRC2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1323318 | 6480464 | Benzoapyrene affects the methylation of LRRC2 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RGD:1323318 | 6480464 | Benzoapyrene results in increased methylation of LRRC2 exon, Benzoapyrene results in increased methylation of LRRC2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | RGD:1323318 | 6480464 | Benzoapyrene results in decreased methylation of LRRC2 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | RGD:1323318 | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | increases methylation | ISO | RGD:1311716 | 6480464 | bisphenol A results in increased methylation of LRRC2 gene | CTD | PMID:28505145 | cyclosporin A | increases expression | ISO | RGD:1323318 | 6480464 | Cyclosporine results in increased expression of LRRC2 mRNA | CTD | PMID:27989131 | DDD | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | DDE | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | DDT | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | dieldrin | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | Endrin | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of LRRC2 mRNA | CTD | PMID:28329830 | fluoranthene | increases expression | EXP | | 6480464 | fluoranthene results in increased expression of LRRC2 mRNA | CTD | PMID:28329830 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of LRRC2 mRNA | CTD | PMID:25629700 | gamma-hexachlorocyclohexane | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of LRRC2 mRNA | CTD | PMID:32186404 | rotenone | increases expression | ISO | RGD:1311716 | 6480464 | Rotenone results in increased expression of LRRC2 mRNA | CTD | PMID:28374803 | serpentine asbestos | increases expression | ISO | RGD:1323318 | 6480464 | Asbestos, Serpentine results in increased expression of LRRC2 mRNA | CTD | PMID:21148743 | silicon dioxide | increases expression | ISO | RGD:1323318 | 6480464 | Silicon Dioxide analog results in increased expression of LRRC2 mRNA | CTD | PMID:25895662 | simvastatin | multiple interactions | ISO | RGD:1323318 | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of LRRC2 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of LRRC2 mRNA | CTD | PMID:29264374 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of LRRC2 mRNA | CTD | PMID:21427059 | valproic acid | increases methylation | ISO | RGD:1323318 | 6480464 | Valproic Acid results in increased methylation of LRRC2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:1323318 | 6480464 | Valproic Acid affects the expression of LRRC2 mRNA | CTD | PMID:25979313 | |