Nphp3 (nephronophthisis 3 (adolescent)) - Rat Genome Database

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Gene: Nphp3 (nephronophthisis 3 (adolescent)) Mus musculus
Analyze
Symbol: Nphp3
Name: nephronophthisis 3 (adolescent)
RGD ID: 1556941
MGI Page MGI
Description: Involved in several processes, including cilium assembly; determination of left/right symmetry; and maintenance of animal organ identity. Acts upstream of or within several processes, including extracellular matrix organization; non-motile cilium assembly; and positive regulation of protein binding activity. Located in ciliary base and ciliary inversin compartment. Is expressed in embryo and secondary heart field. Used to study autosomal dominant polycystic kidney disease and nephronophthisis 3. Human ortholog(s) of this gene implicated in Meckel syndrome 7; Senior-Loken syndrome; nephronophthisis; nephronophthisis 3; and renal-hepatic-pancreatic dysplasia. Orthologous to human NPHP3 (nephrocystin 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3632410F03Rik; AI550417; C230078J01; D330020E01Rik; MGC141550; nephrocystin 3; nephrocystin-3; pc; pcy
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399103,879,743 - 103,921,010 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9103,879,743 - 103,921,017 (+)EnsemblGRCm39 Ensembl
GRCm389104,002,544 - 104,043,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9104,002,544 - 104,043,818 (+)EnsemblGRCm38mm10GRCm38
MGSCv379103,904,874 - 103,946,141 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369103,860,949 - 103,901,892 (+)NCBIMGSCv36mm8
Celera9103,555,338 - 103,596,843 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Bergmann C, etal., Am J Hum Genet. 2008 Apr;82(4):959-70. doi: 10.1016/j.ajhg.2008.02.017. Epub 2008 Mar 27.
2. Overexpression of kidney phosphatidylinositol 4-kinasebeta and phospholipase C(gamma1) proteins in two rodent models of polycystic kidney disease. Cuozzo FP, etal., Biochim Biophys Acta 2002 May 21;1587(1):99-106.
3. Evidence of oligogenic inheritance in nephronophthisis. Hoefele J, etal., J Am Soc Nephrol. 2007 Oct;18(10):2789-95. Epub 2007 Sep 12.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis. Olbrich H, etal., Nat Genet. 2003 Aug;34(4):455-9.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Mutations of NPHP2 and NPHP3 in infantile nephronophthisis. Tory K, etal., Kidney Int. 2009 Apr;75(8):839-47. doi: 10.1038/ki.2008.662. Epub 2009 Jan 28.
Additional References at PubMed
PMID:1385849   PMID:1748176   PMID:1881263   PMID:1883968   PMID:3712587   PMID:7539536   PMID:7559658   PMID:7622841   PMID:7661851   PMID:7919157   PMID:7927664   PMID:8094982  
PMID:8144700   PMID:8636651   PMID:8825940   PMID:9263671   PMID:9329956   PMID:10349636   PMID:10480021   PMID:11042159   PMID:11076861   PMID:11134256   PMID:11544199   PMID:12477932  
PMID:14600027   PMID:15368895   PMID:16141072   PMID:16141073   PMID:17884984   PMID:18185504   PMID:20169535   PMID:20554900   PMID:20562878   PMID:21565611   PMID:21633408   PMID:21873635  
PMID:22328406   PMID:22357932   PMID:22832925   PMID:23852700   PMID:24178445   PMID:24284511   PMID:24815352   PMID:27340223   PMID:27582005   PMID:28205547   PMID:28522687   PMID:28630289  
PMID:29395339   PMID:31928223  


Genomics

Comparative Map Data
Nphp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399103,879,743 - 103,921,010 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9103,879,743 - 103,921,017 (+)EnsemblGRCm39 Ensembl
GRCm389104,002,544 - 104,043,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9104,002,544 - 104,043,818 (+)EnsemblGRCm38mm10GRCm38
MGSCv379103,904,874 - 103,946,141 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369103,860,949 - 103,901,892 (+)NCBIMGSCv36mm8
Celera9103,555,338 - 103,596,843 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.11NCBI
NPHP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383132,680,609 - 132,722,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3132,680,609 - 132,722,432 (-)EnsemblGRCh38hg38GRCh38
GRCh373132,399,453 - 132,441,253 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363133,882,144 - 133,923,966 (-)NCBINCBI36Build 36hg18NCBI36
Build 343133,882,151 - 133,923,974NCBI
Celera3130,824,943 - 130,866,763 (-)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3129,779,095 - 129,821,371 (-)NCBIHuRef
CHM1_13132,362,464 - 132,404,314 (-)NCBICHM1_1
T2T-CHM13v2.03135,425,099 - 135,466,912 (-)NCBIT2T-CHM13v2.0
Nphp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28104,621,908 - 104,662,383 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8104,621,864 - 104,662,383 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8110,269,003 - 110,309,487 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08108,468,194 - 108,508,680 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08106,310,899 - 106,351,380 (+)NCBIRnor_WKY
Rnor_6.08112,526,553 - 112,575,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8112,526,553 - 112,575,745 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08111,913,834 - 111,963,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48109,065,400 - 109,105,882 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8103,986,600 - 104,026,761 (+)NCBICelera
Cytogenetic Map8q32NCBI
Nphp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555015,799,879 - 5,837,022 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555015,799,879 - 5,837,022 (+)NCBIChiLan1.0ChiLan1.0
NPHP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan13130,636,218 - 130,677,487 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03129,753,399 - 129,795,300 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13137,229,994 - 137,271,458 (-)NCBIpanpan1.1PanPan1.1panPan2
NPHP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12329,662,486 - 29,703,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2329,645,641 - 29,703,805 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2329,637,421 - 29,678,561 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02330,176,434 - 30,217,575 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2330,176,684 - 30,217,513 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12329,872,412 - 29,913,301 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02329,929,544 - 29,970,895 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02330,177,261 - 30,218,423 (-)NCBIUU_Cfam_GSD_1.0
Nphp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560269,251,499 - 69,287,758 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365296,009,301 - 6,049,447 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365296,013,321 - 6,048,249 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPHP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1373,858,427 - 73,900,967 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11373,843,770 - 73,901,020 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21381,415,846 - 81,445,656 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPHP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11557,550,878 - 57,629,106 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1557,551,189 - 57,592,661 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604130,538,900 - 30,580,436 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nphp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247308,816,643 - 8,874,649 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247308,824,370 - 8,874,614 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nphp3
1749 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1830
Count of miRNA genes:669
Interacting mature miRNAs:869
Transcripts:ENSMUST00000035167, ENSMUST00000117054, ENSMUST00000129819, ENSMUST00000144937, ENSMUST00000149641
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse

Markers in Region
14.MMHAP63FLE2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389104,006,420 - 104,006,598UniSTSGRCm38
MGSCv379103,908,750 - 103,908,928UniSTSGRCm37
Celera9103,559,213 - 103,559,391UniSTS
Cytogenetic Map9F1UniSTS
cM Map961.0UniSTS
Whitehead_YAC9 UniSTS
AI550417  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389104,043,454 - 104,043,546UniSTSGRCm38
MGSCv379103,945,784 - 103,945,876UniSTSGRCm37
Celera9103,596,486 - 103,596,578UniSTS
Cytogenetic Map9F1UniSTS
cM Map961.0UniSTS
Whitehead/MRC_RH91071.02UniSTS
D9Mgc30  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389104,032,462 - 104,032,607UniSTSGRCm38
MGSCv379103,934,792 - 103,934,937UniSTSGRCm37
Cytogenetic Map9F1UniSTS
cM Map959.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000035167   ⟹   ENSMUSP00000035167
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,879,745 - 103,921,017 (+)Ensembl
GRCm38.p6 Ensembl9104,002,546 - 104,043,818 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191919
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,879,957 - 103,893,885 (+)Ensembl
GRCm38.p6 Ensembl9104,002,758 - 104,016,686 (+)Ensembl
RefSeq Acc Id: ENSMUST00000192485
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,909,059 - 103,911,621 (+)Ensembl
GRCm38.p6 Ensembl9104,031,860 - 104,034,422 (+)Ensembl
RefSeq Acc Id: ENSMUST00000193439   ⟹   ENSMUSP00000141540
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,879,966 - 103,919,543 (+)Ensembl
GRCm38.p6 Ensembl9104,002,767 - 104,042,344 (+)Ensembl
RefSeq Acc Id: ENSMUST00000193642
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,879,743 - 103,916,906 (+)Ensembl
GRCm38.p6 Ensembl9104,002,544 - 104,039,707 (+)Ensembl
RefSeq Acc Id: ENSMUST00000194183   ⟹   ENSMUSP00000142049
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,913,047 - 103,915,711 (+)Ensembl
GRCm38.p6 Ensembl9104,035,848 - 104,038,512 (+)Ensembl
RefSeq Acc Id: ENSMUST00000194774   ⟹   ENSMUSP00000141596
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,879,853 - 103,920,308 (+)Ensembl
GRCm38.p6 Ensembl9104,002,654 - 104,043,109 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216593   ⟹   ENSMUSP00000150368
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9103,917,821 - 103,919,303 (+)Ensembl
GRCm38.p6 Ensembl9104,040,622 - 104,042,104 (+)Ensembl
RefSeq Acc Id: NM_028721   ⟹   NP_082997
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399103,879,743 - 103,921,010 (+)NCBI
GRCm389104,002,544 - 104,043,811 (+)ENTREZGENE
MGSCv379103,904,874 - 103,946,141 (+)RGD
Celera9103,555,338 - 103,596,843 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_172460   ⟹   NP_766048
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399103,879,743 - 103,893,885 (+)NCBI
GRCm389104,002,544 - 104,016,686 (+)NCBI
MGSCv379103,904,874 - 103,946,141 (+)RGD
Celera9103,555,338 - 103,596,843 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_082997   ⟸   NM_028721
- Peptide Label: isoform a
- UniProtKB: Q9D6D1 (UniProtKB/Swiss-Prot),   Q7TNH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_766048   ⟸   NM_172460
- Peptide Label: isoform b
- UniProtKB: Q7TNH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000150368   ⟸   ENSMUST00000216593
RefSeq Acc Id: ENSMUSP00000035167   ⟸   ENSMUST00000035167
RefSeq Acc Id: ENSMUSP00000142049   ⟸   ENSMUST00000194183
RefSeq Acc Id: ENSMUSP00000141540   ⟸   ENSMUST00000193439
RefSeq Acc Id: ENSMUSP00000141596   ⟸   ENSMUST00000194774
Protein Domains
Aminoglycoside phosphotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TNH6-F1-model_v2 AlphaFold Q7TNH6 1-1325 view protein structure

Promoters
RGD ID:6844079
Promoter ID:MM_KWN:58595
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000116516,   ENSMUST00000117054,   NM_028721,   NM_172460,   OTTMUST00000078591,   OTTMUST00000078593,   UC009RHD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369103,904,381 - 103,905,222 (+)MPROMDB
RGD ID:8670652
Promoter ID:EPDNEW_M13357
Type:single initiation site
Name:Nphp3_1
Description:Mus musculus nephronophthisis 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389104,002,583 - 104,002,643EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921275 AgrOrtholog
Ensembl Genes ENSMUSG00000032558 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000035167 ENTREZGENE
  ENSMUSP00000035167.9 UniProtKB/Swiss-Prot
  ENSMUSP00000141540.2 UniProtKB/TrEMBL
  ENSMUSP00000141596.2 UniProtKB/TrEMBL
  ENSMUSP00000142049.2 UniProtKB/TrEMBL
  ENSMUSP00000150368.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035167 ENTREZGENE
  ENSMUST00000035167.15 UniProtKB/Swiss-Prot
  ENSMUST00000191919 ENTREZGENE
  ENSMUST00000193439.6 UniProtKB/TrEMBL
  ENSMUST00000194183.2 UniProtKB/TrEMBL
  ENSMUST00000194774.6 UniProtKB/TrEMBL
  ENSMUST00000216593.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aminoglycoside_PTrfase UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74025 UniProtKB/Swiss-Prot
MGD MGI:1921275 ENTREZGENE
NCBI Gene 74025 ENTREZGENE
PANTHER BETA TRANSDUCIN-RELATED PROTEIN UniProtKB/TrEMBL
  NEPHROCYSTIN-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SI:CH211-212K18.6 UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam APH UniProtKB/TrEMBL
  TPR_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nphp3 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0A6YWG5_MOUSE UniProtKB/TrEMBL
  A0A0A6YXM1_MOUSE UniProtKB/TrEMBL
  A0A1L1STK5_MOUSE UniProtKB/TrEMBL
  H9KV07_MOUSE UniProtKB/TrEMBL
  NPHP3_MOUSE UniProtKB/Swiss-Prot
  Q14BM5_MOUSE UniProtKB/TrEMBL
  Q7TNH5_MOUSE UniProtKB/TrEMBL
  Q7TNH6 ENTREZGENE
  Q9D6D1 ENTREZGENE
UniProt Secondary D6RHB4 UniProtKB/Swiss-Prot
  E9Q5X1 UniProtKB/Swiss-Prot
  E9QN29 UniProtKB/Swiss-Prot
  Q69Z39 UniProtKB/Swiss-Prot
  Q8C798 UniProtKB/Swiss-Prot
  Q8C7Z3 UniProtKB/Swiss-Prot
  Q9D6D1 UniProtKB/Swiss-Prot