Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Nectin1 (nectin cell adhesion molecule 1) Mus musculus
Symbol: Nectin1
Name: nectin cell adhesion molecule 1
Description: Exhibits protein homodimerization activity and signaling receptor activity. Involved in several processes, including camera-type eye development; enamel mineralization; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Localizes to several cellular components, including the cell-cell contact zone; hippocampal mossy fiber to CA3 synapse; and integral component of presynaptic active zone membrane. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Is expressed in brain; cochlea; jaw; olfactory epithelium; and skin. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI835281; AW549174; Cd111; herpes virus entry mediator C; herpesvirus entry mediator C; HIgR; HveC; nectin-1; nectin-1 alpha; nectin-1 delta; poliovirus receptor-related 1; poliovirus receptor-related protein 1; PRR; PRR1; Pvrl1
Homo sapiens (human) : NECTIN1 (nectin cell adhesion molecule 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nectin1 (nectin cell adhesion molecule 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nectin1 (nectin cell adhesion molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NECTIN1 (nectin cell adhesion molecule 1)
Canis lupus familiaris (dog) : NECTIN1 (nectin cell adhesion molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nectin1 (nectin cell adhesion molecule 1)
Sus scrofa (pig) : NECTIN1 (nectin cell adhesion molecule 1)
Chlorocebus sabaeus (green monkey) : NECTIN1 (nectin cell adhesion molecule 1)
Heterocephalus glaber (naked mole-rat) : Nectin1 (nectin cell adhesion molecule 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl943,743,984 - 43,832,658 (+)Ensembl
GRCm38 Ensembl943,743,984 - 43,807,461 (+)Ensembl
GRCm38943,737,075 - 43,807,461 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37943,552,659 - 43,615,544 (+)NCBIGRCm37mm9NCBIm37
MGSCv36943,495,571 - 43,558,456 (+)NCBImm8
Celera941,000,673 - 41,063,599 (+)NCBICelera
Cytogenetic Map9 A5.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nectin1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1556913
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.