Grem2 (gremlin 2, DAN family BMP antagonist) - Rat Genome Database

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Gene: Grem2 (gremlin 2, DAN family BMP antagonist) Mus musculus
Analyze
Symbol: Grem2
Name: gremlin 2, DAN family BMP antagonist
RGD ID: 1556883
MGI Page MGI
Description: Enables BMP binding activity; heparin binding activity; and identical protein binding activity. Involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Located in extracellular space. Is expressed in central nervous system; chondrocranium; integument; and lung. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cysteine knot superfamily 1, BMP antagonist 2; gremlin 2 homolog, cysteine knot superfamily; gremlin-2; Gremlin1; Gremlin2; Pr; Prdc; protein related to DAN and cerberus
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,661,351 - 174,749,484 (-)NCBIGRCm39mm39
GRCm39 Ensembl1174,661,351 - 174,749,385 (-)Ensembl
GRCm381174,833,785 - 174,921,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,833,785 - 174,921,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,763,916 - 176,851,950 (-)NCBIGRCm37mm9NCBIm37
MGSCv361176,670,460 - 176,758,494 (-)NCBImm8
Celera1181,920,779 - 182,009,726 (-)NCBICelera
Cytogenetic Map1H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:9639362   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11748835   PMID:12477932   PMID:15039429   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821  
PMID:17151017   PMID:17222801   PMID:18832392   PMID:19073177   PMID:20534673   PMID:21267068   PMID:21795538   PMID:21873635   PMID:22114682   PMID:22644325   PMID:23063586   PMID:23375831  
PMID:23633963   PMID:23850456   PMID:24648383   PMID:24686385   PMID:25041854   PMID:26273529   PMID:26930384   PMID:27283840   PMID:29794428   PMID:31539501  


Genomics

Comparative Map Data
Grem2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,661,351 - 174,749,484 (-)NCBIGRCm39mm39
GRCm39 Ensembl1174,661,351 - 174,749,385 (-)Ensembl
GRCm381174,833,785 - 174,921,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,833,785 - 174,921,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,763,916 - 176,851,950 (-)NCBIGRCm37mm9NCBIm37
MGSCv361176,670,460 - 176,758,494 (-)NCBImm8
Celera1181,920,779 - 182,009,726 (-)NCBICelera
Cytogenetic Map1H3NCBI
GREM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1240,489,573 - 240,612,155 (-)EnsemblGRCh38hg38GRCh38
GRCh381240,489,573 - 240,612,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371240,652,873 - 240,775,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361238,719,496 - 238,842,085 (-)NCBINCBI36hg18NCBI36
Build 341236,979,833 - 237,101,430NCBI
Celera1213,908,963 - 214,031,592 (-)NCBI
Cytogenetic Map1q43NCBI
HuRef1211,110,745 - 211,233,432 (-)NCBIHuRef
CHM1_11241,924,855 - 242,047,766 (-)NCBICHM1_1
Grem2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21386,778,543 - 86,871,509 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1386,778,500 - 86,871,615 (-)Ensembl
Rnor_6.01392,894,431 - 92,988,137 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1392,894,431 - 92,988,137 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01397,359,449 - 97,453,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41390,528,920 - 90,622,303 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1386,379,414 - 86,472,331 (-)NCBICelera
Cytogenetic Map13q24NCBI
Grem2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540611,245,960 - 11,343,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540611,245,960 - 11,343,677 (+)NCBIChiLan1.0ChiLan1.0
GREM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11221,023,212 - 221,148,149 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1221,026,605 - 221,027,111 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01216,037,977 - 216,163,020 (-)NCBIMhudiblu_PPA_v0panPan3
GREM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1732,048,151 - 32,157,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl732,048,183 - 32,157,146 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha731,588,241 - 31,697,847 (-)NCBI
ROS_Cfam_1.0731,872,605 - 31,982,246 (-)NCBI
UMICH_Zoey_3.1731,710,419 - 31,820,007 (-)NCBI
UNSW_CanFamBas_1.0731,741,770 - 31,851,741 (-)NCBI
UU_Cfam_GSD_1.0731,980,916 - 32,090,573 (-)NCBI
Grem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934444,922,948 - 45,027,019 (-)NCBI
SpeTri2.0NW_0049365269,820,276 - 9,821,907 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GREM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1011,885,280 - 11,885,780 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11011,884,198 - 11,904,249 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21014,102,376 - 14,122,799 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GREM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12577,600,306 - 77,724,090 (-)NCBI
ChlSab1.1 Ensembl2577,602,803 - 77,603,309 (-)Ensembl
Vero_WHO_p1.0NW_02366605579,707,875 - 79,832,479 (-)NCBI
Grem2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477110,965,170 - 11,072,462 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172571254195471971Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167730317195471971Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167730317195471971Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1168222387195471971Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164315658190802075Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167730317195471971Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
1300727Mptp1_mMPTP sensitivity 1 (mouse)Not determined1171804480192998742Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1172250913195471971Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1301333Mop3_mmorphine preference 3 (mouse)Not determined1167929168189571420Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1166092111195471971Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1357854Sle16_msystematic lupus erythematosus susceptibility 16 (mouse)Not determined1169211172177550021Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168481626195471971Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170647303195471971Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1163149528186261999Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
4142389Scfr1_mstem cell frequency regulator 1 (mouse)Not determined171804480189571420Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172571254195471971Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10045887Cplaq13_mcircadian period of locomotor activity 13 (mouse)Not determined1173004198181573094Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
4141878Qrr1_mQTL rich region on chromosome 1 (mouse)Not determined171051174175492500Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172571254195471971Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172800000195471971Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
13207571Tcq11_mtotal cholesterol QTL 11 (mouse)1169310000179820000Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167758517191493284Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172900000195471971Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1215
Count of miRNA genes:607
Interacting mature miRNAs:770
Transcripts:ENSMUST00000055294
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000055294   ⟹   ENSMUSP00000049640
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1174,661,351 - 174,749,385 (-)Ensembl
GRCm38.p6 Ensembl1174,833,785 - 174,921,819 (-)Ensembl
RefSeq Acc Id: NM_011825   ⟹   NP_035955
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,661,351 - 174,749,385 (-)NCBI
GRCm381174,833,785 - 174,921,819 (-)NCBI
MGSCv371176,763,916 - 176,851,950 (-)RGD
Celera1181,920,779 - 182,009,726 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006496826   ⟹   XP_006496889
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,661,352 - 174,749,484 (-)NCBI
GRCm381174,833,786 - 174,921,911 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164647   ⟹   XP_036020540
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,661,352 - 174,749,484 (-)NCBI
RefSeq Acc Id: XM_036164648   ⟹   XP_036020541
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,661,352 - 174,749,484 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_035955   ⟸   NM_011825
- Peptide Label: precursor
- UniProtKB: O88273 (UniProtKB/Swiss-Prot),   Q3TST1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006496889   ⟸   XM_006496826
- Peptide Label: isoform X1
- UniProtKB: O88273 (UniProtKB/Swiss-Prot),   Q3TST1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000049640   ⟸   ENSMUST00000055294
RefSeq Acc Id: XP_036020540   ⟸   XM_036164647
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036020541   ⟸   XM_036164648
- Peptide Label: isoform X1
Protein Domains
CTCK

Promoters
RGD ID:6875836
Promoter ID:EPDNEW_M1369
Type:single initiation site
Name:Grem2_2
Description:Mus musculus gremlin 2, DAN family BMP antagonist , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1370  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381174,875,796 - 174,875,856EPDNEW
RGD ID:6875838
Promoter ID:EPDNEW_M1370
Type:multiple initiation site
Name:Grem2_1
Description:Mus musculus gremlin 2, DAN family BMP antagonist , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1369  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381174,921,820 - 174,921,880EPDNEW
RGD ID:6817866
Promoter ID:MM_KWN:2999
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   Brain,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_011825
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,851,631 - 176,852,131 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1344367 AgrOrtholog
Ensembl Genes ENSMUSG00000050069 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000049640 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000055294 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cys_knot_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gremlin-1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:23893 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1344367 ENTREZGENE
NCBI Gene 23893 ENTREZGENE
Pfam DAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Grem2 PhenoGen
PIRSF Gremlin_precursor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CTCK_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00041 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GREM2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TST1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Grem2  gremlin 2, DAN family BMP antagonist    gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)  Symbol and/or name change 5135510 APPROVED