LOC127267646 (H3K4me1 hESC enhancer GRCh37_chr1:16467866-16468833) - Rat Genome Database

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Gene: LOC127267646 (H3K4me1 hESC enhancer GRCh37_chr1:16467866-16468833) Homo sapiens
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Symbol: LOC127267646
Name: H3K4me1 hESC enhancer GRCh37_chr1:16467866-16468833
RGD ID: 155633236
Description: This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in naive human embryonic stem cells, where it is marked by the H3K4me1 histone modification. This locus also includes an accessible chromatin subregion that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,141,371 - 16,142,338 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37116,467,866 - 16,468,833 (+)NCBIGRCh37GRCh37hg19GRCh37
T2T-CHM13v2.0115,582,751 - 15,583,718 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30033119   PMID:35858748  


Genomics


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Expression

RNA-SEQ Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC127267646 COSMIC
GTEx LOC127267646 GTEx
Human Proteome Map LOC127267646 Human Proteome Map
NCBI Gene LOC127267646 ENTREZGENE