Zfp653 (zinc finger protein 653) - Rat Genome Database

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Gene: Zfp653 (zinc finger protein 653) Mus musculus
Analyze
Symbol: Zfp653
Name: zinc finger protein 653
RGD ID: 1553866
MGI Page MGI
Description: Predicted to enable AF-2 domain binding activity and transcription corepressor activity. Predicted to be involved in extracellular negative regulation of signal transduction; negative regulation of nucleic acid-templated transcription; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus and genitourinary system. Orthologous to human ZNF653 (zinc finger protein 653); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 67 kDa zinc finger protein; E430039K05Rik; zinc finger protein Zip67; Zip67; Znf653
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,966,707 - 21,982,692 (-)NCBIGRCm39mm39
GRCm39 Ensembl921,966,707 - 21,982,672 (-)Ensembl
GRCm38922,055,411 - 22,071,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl922,055,411 - 22,071,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv37921,859,904 - 21,875,789 (-)NCBIGRCm37mm9NCBIm37
MGSCv36921,805,862 - 21,821,747 (-)NCBImm8
Celera919,324,393 - 19,340,278 (-)NCBICelera
Cytogenetic Map9A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:12920234   PMID:15489334   PMID:15618518   PMID:16141072   PMID:16141073  
PMID:18287559   PMID:20059953   PMID:20412781   PMID:21873635  


Genomics

Comparative Map Data
Zfp653
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,966,707 - 21,982,692 (-)NCBIGRCm39mm39
GRCm39 Ensembl921,966,707 - 21,982,672 (-)Ensembl
GRCm38922,055,411 - 22,071,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl922,055,411 - 22,071,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv37921,859,904 - 21,875,789 (-)NCBIGRCm37mm9NCBIm37
MGSCv36921,805,862 - 21,821,747 (-)NCBImm8
Celera919,324,393 - 19,340,278 (-)NCBICelera
Cytogenetic Map9A3NCBI
ZNF653
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1911,483,427 - 11,505,839 (-)EnsemblGRCh38hg38GRCh38
GRCh381911,483,429 - 11,505,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,594,244 - 11,616,654 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,455,246 - 11,477,654 (-)NCBINCBI36hg18NCBI36
Build 341911,455,245 - 11,477,654NCBI
Celera1911,488,980 - 11,511,481 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1911,168,853 - 11,191,511 (-)NCBIHuRef
CHM1_11911,594,307 - 11,616,803 (-)NCBICHM1_1
Zfp653
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2820,586,563 - 20,605,439 (-)NCBI
Rnor_6.0 Ensembl823,066,576 - 23,084,879 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0823,066,576 - 23,085,502 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0823,121,360 - 23,139,963 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4821,161,793 - 21,180,092 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1821,162,095 - 21,180,009 (-)NCBI
Celera821,977,392 - 21,995,212 (-)NCBICelera
Cytogenetic Map8q13NCBI
Znf653
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554952,363,334 - 2,375,654 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554952,363,123 - 2,375,895 (-)NCBIChiLan1.0ChiLan1.0
ZNF653
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11911,740,315 - 11,763,707 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1911,740,585 - 11,763,707 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01911,029,561 - 11,051,967 (-)NCBIMhudiblu_PPA_v0panPan3
ZNF653
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,867,522 - 49,883,889 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,866,056 - 49,883,847 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,738,661 - 49,755,033 (+)NCBI
ROS_Cfam_1.02050,385,820 - 50,402,174 (+)NCBI
UMICH_Zoey_3.12049,596,144 - 49,612,496 (+)NCBI
UNSW_CanFamBas_1.02050,022,286 - 50,038,639 (+)NCBI
UU_Cfam_GSD_1.02050,265,471 - 50,281,817 (+)NCBI
Znf653
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,804,773 - 208,821,172 (+)NCBI
SpeTri2.0NW_0049366591,533,564 - 1,550,106 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF653
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl270,136,442 - 70,154,458 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1270,136,777 - 70,154,458 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2270,489,371 - 70,507,715 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF653
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1610,407,624 - 10,430,246 (-)NCBI
ChlSab1.1 Ensembl610,406,808 - 10,430,029 (-)Ensembl
Vero_WHO_p1.0NW_0236660749,456,192 - 9,479,175 (+)NCBI
Znf653
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248283,250,683 - 3,263,915 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902908Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130430544Mouse
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000022300000Mouse
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756137395074Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9999947243999472Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91245867446458818Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91347987947479879Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91550045549500594Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91550045549500594Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91550045549500594Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91550045549500594Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91583833149838331Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91583833149838331Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91583833149838331Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91610000050100000Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91610000050100000Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91679834550798345Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91706754451067647Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined92003211054032229Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92024206654242196Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92039490154395074Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92039490154395074Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92039490154395074Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92039490154395074Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92094144454941444Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:386
Count of miRNA genes:165
Interacting mature miRNAs:179
Transcripts:ENSMUST00000043922, ENSMUST00000179605
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000043922   ⟹   ENSMUSP00000045895
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl922,055,460 - 22,071,345 (-)Ensembl
RefSeq Acc Id: ENSMUST00000179605   ⟹   ENSMUSP00000137064
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl922,055,700 - 22,071,341 (-)Ensembl
RefSeq Acc Id: ENSMUST00000216244
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl922,063,397 - 22,071,376 (-)Ensembl
RefSeq Acc Id: ENSMUST00000216916
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl922,055,411 - 22,071,276 (-)Ensembl
RefSeq Acc Id: NM_001310759   ⟹   NP_001297688
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39921,966,707 - 21,982,672 (-)NCBI
GRCm38922,055,411 - 22,071,376 (-)NCBI
Sequence:
RefSeq Acc Id: NM_177318   ⟹   NP_796292
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39921,966,707 - 21,982,672 (-)NCBI
GRCm38922,055,411 - 22,071,376 (-)NCBI
MGSCv37921,859,904 - 21,875,789 (-)RGD
Celera919,324,393 - 19,340,278 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006510407   ⟹   XP_006510470
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39921,966,756 - 21,982,692 (-)NCBI
GRCm38922,055,460 - 22,071,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155049   ⟹   XP_036010942
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39921,966,756 - 21,982,691 (-)NCBI
RefSeq Acc Id: XR_001778929
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39921,966,756 - 21,982,691 (-)NCBI
GRCm38922,055,460 - 22,071,395 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_796292   ⟸   NM_177318
- Peptide Label: isoform 2
- UniProtKB: Q6YND2 (UniProtKB/Swiss-Prot),   Q8BHR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006510470   ⟸   XM_006510407
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001297688   ⟸   NM_001310759
- Peptide Label: isoform 1
- UniProtKB: Q8BHR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000137064   ⟸   ENSMUST00000179605
RefSeq Acc Id: ENSMUSP00000045895   ⟸   ENSMUST00000043922
RefSeq Acc Id: XP_036010942   ⟸   XM_036155049
- Peptide Label: isoform X2

Promoters
RGD ID:6845363
Promoter ID:MM_KWN:56607
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000115325,   NM_177318,   UC009ONQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36921,875,569 - 21,876,069 (-)MPROMDB
RGD ID:8669006
Promoter ID:EPDNEW_M12534
Type:initiation region
Name:Zfp653_1
Description:Mus musculus zinc finger protein 653 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38922,071,395 - 22,071,455EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442362 AgrOrtholog
Ensembl Genes ENSMUSG00000038895 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000045895 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000137064 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000043922 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000179605 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report mmu:319601 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2442362 ENTREZGENE
NCBI Gene 319601 ENTREZGENE
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Zfp653 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt Q3TAM8_MOUSE UniProtKB/TrEMBL
  Q6YND2 ENTREZGENE
  Q8BHR7 ENTREZGENE, UniProtKB/TrEMBL
  ZN653_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8BHT8 UniProtKB/Swiss-Prot
  Q8CI02 UniProtKB/Swiss-Prot