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Gene: Kif11 (kinesin family member 11) Mus musculus
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Symbol: Kif11
Name: kinesin family member 11
Description: Predicted to have ATP-dependent microtubule motor activity, plus-end-directed; microtubule binding activity; and protein kinase binding activity. Involved in mitotic centrosome separation and spindle assembly. Predicted to colocalize with the spindle pole. Human ortholog(s) of this gene implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human KIF11 (kinesin family member 11); INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Eg5; Kif8; Kifl1; kinesin 11; kinesin-like 1; kinesin-like protein KIF11; kinesin-related motor protein Eg5; Knsl1
Orthologs:
Homo sapiens (human) : KIF11 (kinesin family member 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kif11 (kinesin family member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kif11 (kinesin family member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : KIF11 (kinesin family member 11)
Canis lupus familiaris (dog) : KIF11 (kinesin family member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kif11 (kinesin family member 11)
Sus scrofa (pig) : KIF11 (kinesin family member 11)
more info ...
Related Pseudogenes: Gm15697   Gm18312  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1937,376,403 - 37,421,859 (+)Ensembl
GRCm381937,376,382 - 37,421,863 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371937,450,893 - 37,496,349 (+)NCBIGRCm37mm9NCBIm37
MGSCv361937,441,547 - 37,487,003 (+)NCBImm8
Celera1938,163,289 - 38,208,645 (+)NCBICelera
Cytogenetic Map19 C2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kif11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553797
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.