Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Adpgk (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ADPGK mRNA] | CTD | PMID:31150632 | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of ADPGK mRNA | CTD | PMID:28960355 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of ADPGK mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADPGK mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of ADPGK mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | ADPGK (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADPGK mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ADPGK mRNA | CTD | PMID:33387578 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ADPGK mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ADPGK mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADPGK mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of ADPGK mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of ADPGK mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ADPGK mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of ADPGK mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ADPGK mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of ADPGK mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ADPGK mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ADPGK mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | ADPGK (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ADPGK mRNA | CTD | PMID:22100608 | alpha-pinene | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ADPGK mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ADPGK mRNA | CTD | PMID:32699268 | amitrole | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of ADPGK mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | ADPGK (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ADPGK mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | ADPGK (Homo sapiens) | 6480464 | Arsenic affects the methylation of ADPGK gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | ADPGK (Homo sapiens) | 6480464 | Arsenic affects the methylation of ADPGK gene | CTD | PMID:25304211 | Azaspiracid | increases expression | ISO | ADPGK (Homo sapiens) | 6480464 | azaspiracid results in increased expression of ADPGK mRNA | CTD | PMID:28939011 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of ADPGK 3' UTR and Benzo(a)pyrene results in increased methylation of ADPGK exon | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ADPGK mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | ADPGK (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ADPGK protein | CTD | PMID:31675489 | bisphenol A | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ADPGK mRNA | CTD | PMID:34947998 | bisphenol F | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ADPGK mRNA | CTD | PMID:28628672 | cadmium dichloride | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of ADPGK mRNA | CTD | PMID:33453195 | carbamazepine | affects expression | ISO | ADPGK (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ADPGK mRNA | CTD | PMID:25979313 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of ADPGK mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ADPGK gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of ADPGK mRNA | CTD | PMID:37019170 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of ADPGK mRNA | CTD | PMID:28472532 | Cuprizon | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of ADPGK mRNA | CTD | PMID:27523638 | dexamethasone | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ADPGK mRNA | CTD | PMID:28628672 | diethylstilbestrol | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in decreased expression of ADPGK mRNA | CTD | PMID:36653537 | dimercaprol | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | Dimercaprol inhibits the reaction [4-aminophenylarsenoxide binds to ADPGK protein] | CTD | PMID:26598702 | doxorubicin | decreases expression | ISO | ADPGK (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ADPGK mRNA | CTD | PMID:29803840 | flutamide | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of ADPGK mRNA | CTD | PMID:24136188 | indometacin | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ADPGK mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | ADPGK (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ADPGK protein | CTD | PMID:32959892 | lead diacetate | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | lead acetate results in decreased expression of ADPGK mRNA | CTD | PMID:22641619 | methamphetamine | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Methamphetamine results in decreased expression of ADPGK mRNA | CTD | PMID:19564919 | methapyrilene | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of ADPGK mRNA | CTD | PMID:30467583 | methimazole | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of ADPGK mRNA | CTD | PMID:30047161 | N,N-diethyl-m-toluamide | multiple interactions | ISO | Adpgk (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of ADPGK gene | CTD | PMID:33148267 | nickel atom | increases expression | ISO | ADPGK (Homo sapiens) | 6480464 | Nickel results in increased expression of ADPGK mRNA | CTD | PMID:25583101 | ozone | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ADPGK mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ADPGK mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of ADPGK mRNA | CTD | PMID:33387578 | perfluorooctanoic acid | decreases expression | ISO | ADPGK (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of ADPGK protein | CTD | PMID:26879310 | permethrin | multiple interactions | ISO | Adpgk (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of ADPGK gene | CTD | PMID:33148267 | phenobarbital | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Phenobarbital results in increased expression of ADPGK mRNA | CTD | PMID:30047161 | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of ADPGK mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | ISO | ADPGK (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of ADPGK mRNA | CTD | PMID:23557933 | Soman | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Soman results in increased expression of ADPGK mRNA | CTD | PMID:19281266 | sulfadimethoxine | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of ADPGK mRNA | CTD | PMID:30047161 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of ADPGK mRNA | CTD | PMID:17555576 | tetrachloromethane | multiple interactions | ISO | Adpgk (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ADPGK mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of ADPGK mRNA | CTD | PMID:31150632 | trichloroethene | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of ADPGK mRNA | CTD | PMID:33387578 | trichostatin A | affects expression | ISO | ADPGK (Homo sapiens) | 6480464 | trichostatin A affects the expression of ADPGK mRNA | CTD | PMID:28542535 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of ADPGK mRNA | CTD | PMID:32835833 | Triptolide | increases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | triptolide results in increased expression of ADPGK mRNA | CTD | PMID:23639586 | triptonide | affects expression | EXP | | 6480464 | triptonide affects the expression of ADPGK mRNA | CTD | PMID:33045310 | triticonazole | decreases expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | triticonazole results in decreased expression of ADPGK mRNA | CTD | PMID:36084822 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of ADPGK mRNA | CTD | PMID:30912803 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ADPGK mRNA | CTD | PMID:17963808 | valproic acid | increases expression | ISO | ADPGK (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ADPGK mRNA | CTD | PMID:23179753 | vinclozolin | affects expression | ISO | Adpgk (Rattus norvegicus) | 6480464 | vinclozolin affects the expression of ADPGK mRNA | CTD | PMID:19015723 | |