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Gene: Fgf8 (fibroblast growth factor 8) Mus musculus
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Symbol: Fgf8
Name: fibroblast growth factor 8
Description: Predicted to have signaling receptor binding activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and positive regulation of protein phosphorylation. Predicted to localize to the external side of plasma membrane and extracellular space. Used to study DiGeorge syndrome and tetralogy of Fallot. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; limb; and sensory organ. Orthologous to human FGF8 (fibroblast growth factor 8); PARTICIPATES IN fibroblast growth factor signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Aigf; androgen-induced growth factor; Fgf-8; HBGF-8; heparin-binding growth factor 8; MGC59627
Orthologs:
Homo sapiens (human) : FGF8 (fibroblast growth factor 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgf8 (fibroblast growth factor 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf8 (fibroblast growth factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF8 (fibroblast growth factor 8)
Canis lupus familiaris (dog) : FGF8 (fibroblast growth factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf8 (fibroblast growth factor 8)
Sus scrofa (pig) : FGF8 (fibroblast growth factor 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1945,736,798 - 45,742,915 (-)Ensembl
GRCm381945,736,798 - 45,742,941 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371945,811,288 - 45,817,374 (-)NCBIGRCm37mm9NCBIm37
MGSCv361945,790,129 - 45,796,184 (-)NCBImm8
Celera1946,499,127 - 46,505,223 (-)NCBICelera
Cytogenetic Map19 C3NCBI
cM Map1938.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fgf8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553752
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.