Or2t48 (olfactory receptor family 2 subfamily T member 48) - Rat Genome Database

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Gene: Or2t48 (olfactory receptor family 2 subfamily T member 48) Mus musculus
Analyze
No known orthologs.
Symbol: Or2t48
Name: olfactory receptor family 2 subfamily T member 48
RGD ID: 1553705
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR2T4 (olfactory receptor family 2 subfamily T member 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2NKPP-895420-896349; MOR275; MOR275-1; olfactory receptor 330; olfactory receptor MOR275-1; Olfr330; RP23-465K20.12
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,419,755 - 58,425,651 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,418,012 - 58,425,662 (-)EnsemblGRCm39 Ensembl
GRCm381158,528,929 - 58,534,825 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,527,186 - 58,534,836 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,342,431 - 58,348,327 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,345,232 - 58,346,179 (-)NCBIMGSCv36mm8
Celera1163,274,500 - 63,280,376 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or2t48
195 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:145
Count of miRNA genes:85
Interacting mature miRNAs:85
Transcripts:ENSMUST00000062869, ENSMUST00000170009
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5406567063319522Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
13513917Heal54_mwound healing/ regeneration 54 (mouse)115787291759879610Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse

Markers in Region
UniSTS:491732  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,528,937 - 58,530,070UniSTSGRCm38
GRCm381158,501,513 - 58,502,658UniSTSGRCm38
MGSCv371158,315,015 - 58,316,160UniSTSGRCm37
MGSCv371158,342,439 - 58,343,572UniSTSGRCm37
Celera1163,274,508 - 63,275,641UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map11B1UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000134055   ⟹   ENSMUSP00000145126
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,419,763 - 58,420,896 (-)Ensembl
GRCm38.p6 Ensembl1158,528,937 - 58,530,070 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213188   ⟹   ENSMUSP00000149073
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,418,012 - 58,425,662 (-)Ensembl
GRCm38.p6 Ensembl1158,527,186 - 58,534,836 (-)Ensembl
RefSeq Acc Id: NM_146879   ⟹   NP_667090
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,419,755 - 58,425,651 (-)NCBI
GRCm381158,528,929 - 58,534,825 (-)ENTREZGENE
MGSCv371158,342,431 - 58,348,327 (-)RGD
Celera1163,274,500 - 63,280,376 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_667090 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI20839 (Get FASTA)   NCBI Sequence Viewer  
  AAL60874 (Get FASTA)   NCBI Sequence Viewer  
  AAP70867 (Get FASTA)   NCBI Sequence Viewer  
  EDL07731 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000145126.2
  ENSMUSP00000149073
  ENSMUSP00000149073.2
RefSeq Acc Id: NP_667090   ⟸   NM_146879
- UniProtKB: Q8VGD9 (UniProtKB/TrEMBL),   Q7TRY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000149073   ⟸   ENSMUST00000213188
RefSeq Acc Id: ENSMUSP00000145126   ⟸   ENSMUST00000134055
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VGD9-F1-model_v2 AlphaFold Q8VGD9 1-315 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030164 AgrOrtholog
Ensembl Genes ENSMUSG00000050818 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000134055.3 UniProtKB/TrEMBL
  ENSMUST00000213188 ENTREZGENE
  ENSMUST00000213188.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258879 UniProtKB/TrEMBL
MGD MGI:3030164 ENTREZGENE
NCBI Gene 258879 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 2T29-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2t48 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TRY9 ENTREZGENE, UniProtKB/TrEMBL
  Q8VGD9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or2t48  olfactory receptor family 2 subfamily T member 48  Olfr330  olfactory receptor 330  Symbol and/or name change 5135510 APPROVED